Tags

Type your tag names separated by a space and hit enter

Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers.
J Infect Dev Ctries. 2013 Oct 15; 7(10):707-12.JI

Abstract

INTRODUCTION

In the present study, we sought to identify the bacterial organisms associated with diabetic foot infections (DFIs) and their antibiotic sensitivity profiles.

METHODOLOGY

We retrospectively reviewed the records of wound cultures collected from diabetic patients with foot infections between May 2005 and July 2010.

RESULTS

We identified a total of 298 culture specimens (165 [55%] wound swab, 108 [36%] tissue samples, and 25 [9%] bone samples) from 107 patients (74 [69%] males and 33 [31%] females, mean age 62 ± 13 yr) with a DFI. Among all cultures 83.5% (223/267) were monomicrobial and 16.4% (44/267) were polymicrobial. Gram-negative bacterial isolates (n = 191; 61.3%) significantly outnumbered Gram-positive isolates (n = 121; 38.7%). The most frequently isolated bacteria were Pseudomonas species (29.8%), Staphylococcus aureus (16.7%), Enterococcus species (11.5%), Escherichia coli (7.1%), and Enterobacter species (7.1%), respectively. While 13.2% of the Gram-negative isolates were inducible beta-lactamase positive, 44.2% of Staphylococcus aureus isolates were methicillin resistant.

CONCLUSIONS

Our results support the recent view that Gram-negative organisms, depending on the geographical location, may predominate in DFIs.

Authors+Show Affiliations

Gata Haydarpasa Training Hospital, Istanbul, Turkey. vedatturhan@yahoo.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24129622

Citation

Turhan, Vedat, et al. "Increasing Incidence of Gram-negative Organisms in Bacterial Agents Isolated From Diabetic Foot Ulcers." Journal of Infection in Developing Countries, vol. 7, no. 10, 2013, pp. 707-12.
Turhan V, Mutluoglu M, Acar A, et al. Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers. J Infect Dev Ctries. 2013;7(10):707-12.
Turhan, V., Mutluoglu, M., Acar, A., Hatipoğlu, M., Önem, Y., Uzun, G., Ay, H., Öncül, O., & Görenek, L. (2013). Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers. Journal of Infection in Developing Countries, 7(10), 707-12. https://doi.org/10.3855/jidc.2967
Turhan V, et al. Increasing Incidence of Gram-negative Organisms in Bacterial Agents Isolated From Diabetic Foot Ulcers. J Infect Dev Ctries. 2013 Oct 15;7(10):707-12. PubMed PMID: 24129622.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increasing incidence of Gram-negative organisms in bacterial agents isolated from diabetic foot ulcers. AU - Turhan,Vedat, AU - Mutluoglu,Mesut, AU - Acar,Ali, AU - Hatipoğlu,Mustafa, AU - Önem,Yalçın, AU - Uzun,Gunalp, AU - Ay,Hakan, AU - Öncül,Oral, AU - Görenek,Levent, Y1 - 2013/10/15/ PY - 2012/08/30/received PY - 2013/01/28/accepted PY - 2013/10/11/revised PY - 2013/10/17/entrez PY - 2013/10/17/pubmed PY - 2014/5/7/medline SP - 707 EP - 12 JF - Journal of infection in developing countries JO - J Infect Dev Ctries VL - 7 IS - 10 N2 - INTRODUCTION: In the present study, we sought to identify the bacterial organisms associated with diabetic foot infections (DFIs) and their antibiotic sensitivity profiles. METHODOLOGY: We retrospectively reviewed the records of wound cultures collected from diabetic patients with foot infections between May 2005 and July 2010. RESULTS: We identified a total of 298 culture specimens (165 [55%] wound swab, 108 [36%] tissue samples, and 25 [9%] bone samples) from 107 patients (74 [69%] males and 33 [31%] females, mean age 62 ± 13 yr) with a DFI. Among all cultures 83.5% (223/267) were monomicrobial and 16.4% (44/267) were polymicrobial. Gram-negative bacterial isolates (n = 191; 61.3%) significantly outnumbered Gram-positive isolates (n = 121; 38.7%). The most frequently isolated bacteria were Pseudomonas species (29.8%), Staphylococcus aureus (16.7%), Enterococcus species (11.5%), Escherichia coli (7.1%), and Enterobacter species (7.1%), respectively. While 13.2% of the Gram-negative isolates were inducible beta-lactamase positive, 44.2% of Staphylococcus aureus isolates were methicillin resistant. CONCLUSIONS: Our results support the recent view that Gram-negative organisms, depending on the geographical location, may predominate in DFIs. SN - 1972-2680 UR - https://www.unboundmedicine.com/medline/citation/24129622/Increasing_incidence_of_Gram_negative_organisms_in_bacterial_agents_isolated_from_diabetic_foot_ulcers_ L2 - http://www.jidc.org/index.php/journal/article/view/24129622 DB - PRIME DP - Unbound Medicine ER -