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Antigliadin antibodies and gluten-free diet in dermatitis herpetiformis.
Acta Derm Venereol. 1985; 65(4):291-7.AD

Abstract

IgA and IgG class antigliadin antibodies (AGA) were analysed with ELISA technique from serum samples of 30 dermatitis herpetiformis patients. Jejunal biopsies were performed to all patients before any treatment and high levels of IgA class AGA were found to be associated with subtotal villous atrophy. Fourteen patients started gluten-free diet (GFD) which caused a significant decrease in both IgA and IgG class AGA. The decrease of IgA AGA was faster than that of IgG AGA and IgA antibody levels fell to normal range during the GFD treatment in all but one patient. In contrast, 5 out of 8 patients followed on normal died showed increasing IgA AGA levels and all of them had a rise in IgG AGA. IgA and IgG class antibodies to cow's milk were also measured in these patients but in contrast to AGA the diets had no clearcut effect on these antibodies.

Authors

Vainio E
No affiliation info available
Kalimo K
No affiliation info available
Viander M
No affiliation info available
Reunala T
No affiliation info available

MeSH

AdolescentAdultAntibodiesCeliac DiseaseDermatitis HerpetiformisDietary ProteinsGliadinGlutensHumansImmunoglobulin AImmunoglobulin GJejunumMiddle AgedPlant Proteins

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2413682

Citation

Vainio, E, et al. "Antigliadin Antibodies and Gluten-free Diet in Dermatitis Herpetiformis." Acta Dermato-venereologica, vol. 65, no. 4, 1985, pp. 291-7.
Vainio E, Kalimo K, Viander M, et al. Antigliadin antibodies and gluten-free diet in dermatitis herpetiformis. Acta Derm Venereol. 1985;65(4):291-7.
Vainio, E., Kalimo, K., Viander, M., & Reunala, T. (1985). Antigliadin antibodies and gluten-free diet in dermatitis herpetiformis. Acta Dermato-venereologica, 65(4), 291-7.
Vainio E, et al. Antigliadin Antibodies and Gluten-free Diet in Dermatitis Herpetiformis. Acta Derm Venereol. 1985;65(4):291-7. PubMed PMID: 2413682.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antigliadin antibodies and gluten-free diet in dermatitis herpetiformis. AU - Vainio,E, AU - Kalimo,K, AU - Viander,M, AU - Reunala,T, PY - 1985/1/1/pubmed PY - 1985/1/1/medline PY - 1985/1/1/entrez SP - 291 EP - 7 JF - Acta dermato-venereologica JO - Acta Derm Venereol VL - 65 IS - 4 N2 - IgA and IgG class antigliadin antibodies (AGA) were analysed with ELISA technique from serum samples of 30 dermatitis herpetiformis patients. Jejunal biopsies were performed to all patients before any treatment and high levels of IgA class AGA were found to be associated with subtotal villous atrophy. Fourteen patients started gluten-free diet (GFD) which caused a significant decrease in both IgA and IgG class AGA. The decrease of IgA AGA was faster than that of IgG AGA and IgA antibody levels fell to normal range during the GFD treatment in all but one patient. In contrast, 5 out of 8 patients followed on normal died showed increasing IgA AGA levels and all of them had a rise in IgG AGA. IgA and IgG class antibodies to cow's milk were also measured in these patients but in contrast to AGA the diets had no clearcut effect on these antibodies. SN - 0001-5555 UR - https://www.unboundmedicine.com/medline/citation/2413682/Antigliadin_antibodies_and_gluten_free_diet_in_dermatitis_herpetiformis_ DB - PRIME DP - Unbound Medicine ER -