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Pandoraviruses are highly derived phycodnaviruses.
Biol Direct. 2013 Oct 23; 8:25.BD

Abstract

The recently discovered Pandoraviruses are by far the largest viruses known, with their 2 megabase genomes exceeding in size the genomes of numerous bacteria and archaea. Pandoraviruses show a distant relationship with other nucleocytoplasmic large DNA viruses (NCLDV) of eukaryotes, lack some of the NCLDV core genes and in particular do not appear to be specifically related to the other, better characterized family of giant viruses, the Mimiviridae. Here we report phylogenetic analysis of 6 core NCLDV genes that confidently places Pandoraviruses within the family Phycodnaviridae, with an apparent specific affinity with Coccolithoviruses. We conclude that, despite their many unusual characteristics, Pandoraviruses are highly derived phycodnaviruses. These findings imply that giant viruses have independently evolved from smaller NCLDV on at least two occasions.

Authors+Show Affiliations

No affiliation info availableNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA. koonin@ncbi.nlm.nih.gov.

Pub Type(s)

Journal Article
Research Support, N.I.H., Intramural

Language

eng

PubMed ID

24148757

Citation

Yutin, Natalya, and Eugene V. Koonin. "Pandoraviruses Are Highly Derived Phycodnaviruses." Biology Direct, vol. 8, 2013, p. 25.
Yutin N, Koonin EV. Pandoraviruses are highly derived phycodnaviruses. Biol Direct. 2013;8:25.
Yutin, N., & Koonin, E. V. (2013). Pandoraviruses are highly derived phycodnaviruses. Biology Direct, 8, 25. https://doi.org/10.1186/1745-6150-8-25
Yutin N, Koonin EV. Pandoraviruses Are Highly Derived Phycodnaviruses. Biol Direct. 2013 Oct 23;8:25. PubMed PMID: 24148757.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pandoraviruses are highly derived phycodnaviruses. AU - Yutin,Natalya, AU - Koonin,Eugene V, Y1 - 2013/10/23/ PY - 2013/09/16/received PY - 2013/10/16/accepted PY - 2013/10/24/entrez PY - 2013/10/24/pubmed PY - 2014/6/10/medline SP - 25 EP - 25 JF - Biology direct JO - Biol Direct VL - 8 N2 - The recently discovered Pandoraviruses are by far the largest viruses known, with their 2 megabase genomes exceeding in size the genomes of numerous bacteria and archaea. Pandoraviruses show a distant relationship with other nucleocytoplasmic large DNA viruses (NCLDV) of eukaryotes, lack some of the NCLDV core genes and in particular do not appear to be specifically related to the other, better characterized family of giant viruses, the Mimiviridae. Here we report phylogenetic analysis of 6 core NCLDV genes that confidently places Pandoraviruses within the family Phycodnaviridae, with an apparent specific affinity with Coccolithoviruses. We conclude that, despite their many unusual characteristics, Pandoraviruses are highly derived phycodnaviruses. These findings imply that giant viruses have independently evolved from smaller NCLDV on at least two occasions. SN - 1745-6150 UR - https://www.unboundmedicine.com/medline/citation/24148757/Pandoraviruses_are_highly_derived_phycodnaviruses_ L2 - https://biologydirect.biomedcentral.com/articles/10.1186/1745-6150-8-25 DB - PRIME DP - Unbound Medicine ER -