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Human monkeypox.
Clin Infect Dis. 2014 Jan; 58(2):260-7.CI

Abstract

Human monkeypox is a zoonotic Orthopoxvirus with a presentation similar to smallpox. Clinical differentiation of the disease from smallpox and varicella is difficult. Laboratory diagnostics are principal components to identification and surveillance of disease, and new tests are needed for a more precise and rapid diagnosis. The majority of human infections occur in Central Africa, where surveillance in rural areas with poor infrastructure is difficult but can be accomplished with evidence-guided tools and educational materials to inform public health workers of important principles. Contemporary epidemiological studies are needed now that populations do not receive routine smallpox vaccination. New therapeutics and vaccines offer hope for the treatment and prevention of monkeypox; however, more research must be done before they are ready to be deployed in an endemic setting. There is a need for more research in the epidemiology, ecology, and biology of the virus in endemic areas to better understand and prevent human infections.

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Authors+Show Affiliations

McCollum AM
Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Damon IK
No affiliation info available

MeSH

Africa, CentralAnimalsCommunicable Diseases, EmergingEndemic DiseasesHumansMonkeypoxOrthopoxvirusRural PopulationZoonoses

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

24158414

Citation

McCollum, Andrea M., and Inger K. Damon. "Human Monkeypox." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 58, no. 2, 2014, pp. 260-7.
McCollum AM, Damon IK. Human monkeypox. Clin Infect Dis. 2014;58(2):260-7.
McCollum, A. M., & Damon, I. K. (2014). Human monkeypox. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 58(2), 260-7. https://doi.org/10.1093/cid/cit703
McCollum AM, Damon IK. Human Monkeypox. Clin Infect Dis. 2014;58(2):260-7. PubMed PMID: 24158414.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Human monkeypox. AU - McCollum,Andrea M, AU - Damon,Inger K, Y1 - 2013/10/24/ PY - 2013/10/26/entrez PY - 2013/10/26/pubmed PY - 2014/8/21/medline KW - Orthopoxvirus KW - monkeypox KW - smallpox SP - 260 EP - 7 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 58 IS - 2 N2 - Human monkeypox is a zoonotic Orthopoxvirus with a presentation similar to smallpox. Clinical differentiation of the disease from smallpox and varicella is difficult. Laboratory diagnostics are principal components to identification and surveillance of disease, and new tests are needed for a more precise and rapid diagnosis. The majority of human infections occur in Central Africa, where surveillance in rural areas with poor infrastructure is difficult but can be accomplished with evidence-guided tools and educational materials to inform public health workers of important principles. Contemporary epidemiological studies are needed now that populations do not receive routine smallpox vaccination. New therapeutics and vaccines offer hope for the treatment and prevention of monkeypox; however, more research must be done before they are ready to be deployed in an endemic setting. There is a need for more research in the epidemiology, ecology, and biology of the virus in endemic areas to better understand and prevent human infections. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/24158414/Human_monkeypox_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1093/cid/cit703 DB - PRIME DP - Unbound Medicine ER -