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Fatty fish intake is associated with decreased occurrence of multiple sclerosis.

Abstract

BACKGROUND

High vitamin D levels have been associated with a decreased risk of developing multiple sclerosis (MS). The most important source of dietary vitamin D is fatty fish.

OBJECTIVE

The objective of this paper is to investigate the association between fish consumption and the risk of MS, including the interaction between fish intake and ultraviolet radiation (UVR) exposure habits.

METHODS

This study is based on the project Epidemiological Investigation of MS (EIMS), which is a Swedish population-based case-control study. The analysis included 1879 incident cases of MS and 4135 controls. Subjects who reported high fatty fish intake were compared regarding occurrence of MS with those who reported low intake by calculating odds ratio (OR) with 95% confidence interval (CI).

RESULTS

Frequent fatty fish intake was associated with decreased occurrence of MS (adjusted OR 0.82 (95% CI 0.68-0.98). There was no significant association between intake of lean fish and MS.

CONCLUSION

Fatty fish intake might decrease the risk for MS. A hypothetical explanation is that intake of fatty fish may compensate for vitamin D deficiency that is associated with increased MS risk.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Institute of Environmental Medicine, Karolinska Institutet, Sweden.

    ,

    Source

    MeSH

    Adult
    Aged
    Case-Control Studies
    Diet
    Eating
    Fats
    Female
    Humans
    Male
    Middle Aged
    Multiple Sclerosis
    Risk
    Risk Factors
    Seafood
    Vitamin D
    Young Adult

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    24158977

    Citation

    Bäärnhielm, Maria, et al. "Fatty Fish Intake Is Associated With Decreased Occurrence of Multiple Sclerosis." Multiple Sclerosis (Houndmills, Basingstoke, England), vol. 20, no. 6, 2014, pp. 726-32.
    Bäärnhielm M, Olsson T, Alfredsson L. Fatty fish intake is associated with decreased occurrence of multiple sclerosis. Mult Scler. 2014;20(6):726-32.
    Bäärnhielm, M., Olsson, T., & Alfredsson, L. (2014). Fatty fish intake is associated with decreased occurrence of multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England), 20(6), pp. 726-32. doi:10.1177/1352458513509508.
    Bäärnhielm M, Olsson T, Alfredsson L. Fatty Fish Intake Is Associated With Decreased Occurrence of Multiple Sclerosis. Mult Scler. 2014;20(6):726-32. PubMed PMID: 24158977.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Fatty fish intake is associated with decreased occurrence of multiple sclerosis. AU - Bäärnhielm,Maria, AU - Olsson,Tomas, AU - Alfredsson,Lars, Y1 - 2013/10/24/ PY - 2013/10/26/entrez PY - 2013/10/26/pubmed PY - 2015/3/31/medline KW - Multiple sclerosis KW - case-control study KW - epidemiology KW - fatty fish KW - ultraviolet radiation (UVR) exposure KW - vitamin D SP - 726 EP - 32 JF - Multiple sclerosis (Houndmills, Basingstoke, England) JO - Mult. Scler. VL - 20 IS - 6 N2 - BACKGROUND: High vitamin D levels have been associated with a decreased risk of developing multiple sclerosis (MS). The most important source of dietary vitamin D is fatty fish. OBJECTIVE: The objective of this paper is to investigate the association between fish consumption and the risk of MS, including the interaction between fish intake and ultraviolet radiation (UVR) exposure habits. METHODS: This study is based on the project Epidemiological Investigation of MS (EIMS), which is a Swedish population-based case-control study. The analysis included 1879 incident cases of MS and 4135 controls. Subjects who reported high fatty fish intake were compared regarding occurrence of MS with those who reported low intake by calculating odds ratio (OR) with 95% confidence interval (CI). RESULTS: Frequent fatty fish intake was associated with decreased occurrence of MS (adjusted OR 0.82 (95% CI 0.68-0.98). There was no significant association between intake of lean fish and MS. CONCLUSION: Fatty fish intake might decrease the risk for MS. A hypothetical explanation is that intake of fatty fish may compensate for vitamin D deficiency that is associated with increased MS risk. SN - 1477-0970 UR - https://www.unboundmedicine.com/medline/citation/24158977/Fatty_fish_intake_is_associated_with_decreased_occurrence_of_multiple_sclerosis_ L2 - http://journals.sagepub.com/doi/full/10.1177/1352458513509508?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -