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Fatty fish intake is associated with decreased occurrence of multiple sclerosis.
Mult Scler 2014; 20(6):726-32MS

Abstract

BACKGROUND

High vitamin D levels have been associated with a decreased risk of developing multiple sclerosis (MS). The most important source of dietary vitamin D is fatty fish.

OBJECTIVE

The objective of this paper is to investigate the association between fish consumption and the risk of MS, including the interaction between fish intake and ultraviolet radiation (UVR) exposure habits.

METHODS

This study is based on the project Epidemiological Investigation of MS (EIMS), which is a Swedish population-based case-control study. The analysis included 1879 incident cases of MS and 4135 controls. Subjects who reported high fatty fish intake were compared regarding occurrence of MS with those who reported low intake by calculating odds ratio (OR) with 95% confidence interval (CI).

RESULTS

Frequent fatty fish intake was associated with decreased occurrence of MS (adjusted OR 0.82 (95% CI 0.68-0.98). There was no significant association between intake of lean fish and MS.

CONCLUSION

Fatty fish intake might decrease the risk for MS. A hypothetical explanation is that intake of fatty fish may compensate for vitamin D deficiency that is associated with increased MS risk.

Authors+Show Affiliations

Institute of Environmental Medicine, Karolinska Institutet, Sweden.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24158977

Citation

Bäärnhielm, Maria, et al. "Fatty Fish Intake Is Associated With Decreased Occurrence of Multiple Sclerosis." Multiple Sclerosis (Houndmills, Basingstoke, England), vol. 20, no. 6, 2014, pp. 726-32.
Bäärnhielm M, Olsson T, Alfredsson L. Fatty fish intake is associated with decreased occurrence of multiple sclerosis. Mult Scler. 2014;20(6):726-32.
Bäärnhielm, M., Olsson, T., & Alfredsson, L. (2014). Fatty fish intake is associated with decreased occurrence of multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England), 20(6), pp. 726-32. doi:10.1177/1352458513509508.
Bäärnhielm M, Olsson T, Alfredsson L. Fatty Fish Intake Is Associated With Decreased Occurrence of Multiple Sclerosis. Mult Scler. 2014;20(6):726-32. PubMed PMID: 24158977.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fatty fish intake is associated with decreased occurrence of multiple sclerosis. AU - Bäärnhielm,Maria, AU - Olsson,Tomas, AU - Alfredsson,Lars, Y1 - 2013/10/24/ PY - 2013/10/26/entrez PY - 2013/10/26/pubmed PY - 2015/3/31/medline KW - Multiple sclerosis KW - case-control study KW - epidemiology KW - fatty fish KW - ultraviolet radiation (UVR) exposure KW - vitamin D SP - 726 EP - 32 JF - Multiple sclerosis (Houndmills, Basingstoke, England) JO - Mult. Scler. VL - 20 IS - 6 N2 - BACKGROUND: High vitamin D levels have been associated with a decreased risk of developing multiple sclerosis (MS). The most important source of dietary vitamin D is fatty fish. OBJECTIVE: The objective of this paper is to investigate the association between fish consumption and the risk of MS, including the interaction between fish intake and ultraviolet radiation (UVR) exposure habits. METHODS: This study is based on the project Epidemiological Investigation of MS (EIMS), which is a Swedish population-based case-control study. The analysis included 1879 incident cases of MS and 4135 controls. Subjects who reported high fatty fish intake were compared regarding occurrence of MS with those who reported low intake by calculating odds ratio (OR) with 95% confidence interval (CI). RESULTS: Frequent fatty fish intake was associated with decreased occurrence of MS (adjusted OR 0.82 (95% CI 0.68-0.98). There was no significant association between intake of lean fish and MS. CONCLUSION: Fatty fish intake might decrease the risk for MS. A hypothetical explanation is that intake of fatty fish may compensate for vitamin D deficiency that is associated with increased MS risk. SN - 1477-0970 UR - https://www.unboundmedicine.com/medline/citation/24158977/Fatty_fish_intake_is_associated_with_decreased_occurrence_of_multiple_sclerosis_ L2 - http://journals.sagepub.com/doi/full/10.1177/1352458513509508?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -