Tags

Type your tag names separated by a space and hit enter

Drugs for Parkinson's disease.
Treat Guidel Med Lett. 2013 Nov; 11(135):101-6.TG

Abstract

Levodopa combined with carbidopa is still the most effective treatment for symptoms of Parkinson's disease. Dopamine agonists, the next most effective class of drugs, can be used alone before the introduction of levodopa or as an adjunct to levodopa.Addition of a peripherally-acting COMT inhibitor or an MAO-B inhibitor to levodopa can reduce motor fluctuations in patients with advanced disease.Amantadine may have mild symptomatic benefit and can decrease levodopa-induced dyskinesias.Anticholinergics are rarely used because of their adverse effects, but can be a useful addition to levodopa for control of tremor and drooling.Subcutaneous apomorphine should be available for rescue use in patients with 'off' episodes. Deep brain stimulation is an option for patients with levodopa-induced motor complications and relatively intact cognition.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24165688

Citation

"Drugs for Parkinson's Disease." Treatment Guidelines From the Medical Letter, vol. 11, no. 135, 2013, pp. 101-6.
Drugs for Parkinson's disease. Treat Guidel Med Lett. 2013;11(135):101-6.
(2013). Drugs for Parkinson's disease. Treatment Guidelines From the Medical Letter, 11(135), 101-6.
Drugs for Parkinson's Disease. Treat Guidel Med Lett. 2013;11(135):101-6. PubMed PMID: 24165688.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Drugs for Parkinson's disease. PY - 2013/10/30/entrez PY - 2013/10/30/pubmed PY - 2014/6/3/medline SP - 101 EP - 6 JF - Treatment guidelines from the Medical Letter JO - Treat Guidel Med Lett VL - 11 IS - 135 N2 - Levodopa combined with carbidopa is still the most effective treatment for symptoms of Parkinson's disease. Dopamine agonists, the next most effective class of drugs, can be used alone before the introduction of levodopa or as an adjunct to levodopa.Addition of a peripherally-acting COMT inhibitor or an MAO-B inhibitor to levodopa can reduce motor fluctuations in patients with advanced disease.Amantadine may have mild symptomatic benefit and can decrease levodopa-induced dyskinesias.Anticholinergics are rarely used because of their adverse effects, but can be a useful addition to levodopa for control of tremor and drooling.Subcutaneous apomorphine should be available for rescue use in patients with 'off' episodes. Deep brain stimulation is an option for patients with levodopa-induced motor complications and relatively intact cognition. SN - 1541-2792 UR - https://www.unboundmedicine.com/medline/citation/24165688/Drugs_for_Parkinson's_disease_ L2 - http://www.medicalletter.org/scripts/articlefind.cgi?issue=135&page=101 DB - PRIME DP - Unbound Medicine ER -