Citation
Nutt, J G., et al. "Mobility, Mood and Site of Care Impact Health Related Quality of Life in Parkinson's Disease." Parkinsonism & Related Disorders, vol. 20, no. 3, 2014, pp. 274-9.
Nutt JG, Siderowf AD, Guttman M, et al. Mobility, mood and site of care impact health related quality of life in Parkinson's disease. Parkinsonism Relat Disord. 2014;20(3):274-9.
Nutt, J. G., Siderowf, A. D., Guttman, M., Schmidt, P. N., Zamudio, J. I., Wu, S. S., Okun, M. S., Simuni, T., Parashos, S. A., Dahodwala, N. A., Davis, T. L., Giladi, N., Gurevich, T., Hauser, R. A., Jankovic, J., Lyons, K. E., Marsh, L., Miyasaki, J. M., Morgan, J. C., ... Nelson, E. C. (2014). Mobility, mood and site of care impact health related quality of life in Parkinson's disease. Parkinsonism & Related Disorders, 20(3), 274-9. https://doi.org/10.1016/j.parkreldis.2013.10.004
Nutt JG, et al. Mobility, Mood and Site of Care Impact Health Related Quality of Life in Parkinson's Disease. Parkinsonism Relat Disord. 2014;20(3):274-9. PubMed PMID: 24182524.
TY - JOUR
T1 - Mobility, mood and site of care impact health related quality of life in Parkinson's disease.
AU - Nutt,J G,
AU - Siderowf,A D,
AU - Guttman,M,
AU - Schmidt,P N,
AU - Zamudio,J I,
AU - Wu,S S,
AU - Okun,M S,
AU - Simuni,T,
AU - Parashos,S A,
AU - Dahodwala,N A,
AU - Davis,T L,
AU - Giladi,N,
AU - Gurevich,T,
AU - Hauser,R A,
AU - Jankovic,J,
AU - Lyons,K E,
AU - Marsh,L,
AU - Miyasaki,J M,
AU - Morgan,J C,
AU - Santiago,A J,
AU - Tarsy,D,
AU - Mari,Z,
AU - Malaty,I A,
AU - Nelson,E C,
AU - ,,
Y1 - 2013/10/16/
PY - 2013/07/30/received
PY - 2013/10/04/revised
PY - 2013/10/08/accepted
PY - 2013/11/5/entrez
PY - 2013/11/5/pubmed
PY - 2014/12/15/medline
KW - Best practices
KW - Health related quality of life
KW - Parkinson's disease
KW - Quality improvement
SP - 274
EP - 9
JF - Parkinsonism & related disorders
JO - Parkinsonism Relat Disord
VL - 20
IS - 3
N2 - OBJECTIVE: Examine the correlates of Health Related Quality of Life (HRQL) in a large cohort of Parkinson's disease (PD) patients from National Parkinson Foundation (NPF) Centers of Excellence (COEs). BACKGROUND: Improving outcomes for PD will depend upon uncovering disease features impacting HRQL to identify targets for intervention and variables for risk-adjustment models. Differences in HRQL outcomes between COEs could uncover modifiable aspects of care delivery. METHODS: This cross-sectional study examined the relative contribution of demographic, social, clinical and treatment features potentially related to HRQL, as measured by the PDQ-39, in 4601 consecutive subjects from 18 COEs. Stepwise linear regression was utilized to identify correlates of HRQL. RESULTS: The variability in the PDQ-39 summary index score correlated with H&Y stage (R(2) = 22%), Timed up and Go (TUG) (17%), disease duration (11%), comorbidities (8%), cognitive status (8%), antidepressant use (6%) and center at which a patient received care (5%). Stepwise regression reordered the importance of the variables, with the H&Y first and TUG and the center becoming equal and the second most important variables determining the PDQ-39 total score. All independent variables together accounted for 44% of the variability in HRQL. CONCLUSIONS: We confirmed many but not all HRQL associations found in smaller studies. A novel observation was that the site of care was an important contributor to HRQL, suggesting that comparison of outcomes and processes among centers may identify best practices.
SN - 1873-5126
UR - https://www.unboundmedicine.com/medline/citation/24182524/Mobility_mood_and_site_of_care_impact_health_related_quality_of_life_in_Parkinson's_disease_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S1353-8020(13)00359-3
DB - PRIME
DP - Unbound Medicine
ER -