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Adherence to predefined dietary patterns and incident type 2 diabetes in European populations: EPIC-InterAct Study.
Diabetologia 2014; 57(2):321-33D

Abstract

AIMS/HYPOTHESIS

Few studies have investigated the relationship between predefined dietary patterns and type 2 diabetes incidence; little is known about the generalisability of these associations. We aimed to assess the association between predefined dietary patterns and type 2 diabetes risk in European populations.

METHODS

From among a case-cohort of 12,403 incident diabetes cases and 16,154 subcohort members nested within the prospective European Prospective Investigation into Cancer and Nutrition study, we used data on 9,682 cases and 12,595 subcohort participants from seven countries. Habitual dietary intake was assessed at baseline with country-specific dietary questionnaires. Two diet-quality scores (alternative Healthy Eating Index [aHEI], Dietary Approaches to Stop Hypertension [DASH] score) and three reduced rank regression (RRR)-derived dietary-pattern scores were constructed. Country-specific HRs were calculated and combined using a random-effects meta-analysis.

RESULTS

After multivariable adjustment, including body size, the aHEI and DASH scores were not significantly associated with diabetes, although for the aHEI there was a tendency towards an inverse association in countries with higher mean age. We observed inverse associations of the three RRR-derived dietary-pattern scores with diabetes: HRs (95% CIs) for a 1-SD difference were 0.91 (0.86, 0.96), 0.92 (0.84, 1.01) and 0.87 (0.82, 0.92). Random-effects meta-analyses revealed heterogeneity between countries that was explainable by differences in the age of participants or the distribution of dietary intake.

CONCLUSIONS/INTERPRETATION

Adherence to specific RRR-derived dietary patterns, commonly characterised by high intake of fruits or vegetables and low intake of processed meat, sugar-sweetened beverages and refined grains, may lower type 2 diabetes risk.

Authors

No affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24196190

Citation

InterAct Consortium. "Adherence to Predefined Dietary Patterns and Incident Type 2 Diabetes in European Populations: EPIC-InterAct Study." Diabetologia, vol. 57, no. 2, 2014, pp. 321-33.
InterAct Consortium. Adherence to predefined dietary patterns and incident type 2 diabetes in European populations: EPIC-InterAct Study. Diabetologia. 2014;57(2):321-33.
InterAct Consortium. (2014). Adherence to predefined dietary patterns and incident type 2 diabetes in European populations: EPIC-InterAct Study. Diabetologia, 57(2), pp. 321-33. doi:10.1007/s00125-013-3092-9.
InterAct Consortium. Adherence to Predefined Dietary Patterns and Incident Type 2 Diabetes in European Populations: EPIC-InterAct Study. Diabetologia. 2014;57(2):321-33. PubMed PMID: 24196190.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adherence to predefined dietary patterns and incident type 2 diabetes in European populations: EPIC-InterAct Study. A1 - ,, Y1 - 2013/11/07/ PY - 2013/05/11/received PY - 2013/09/23/accepted PY - 2013/11/8/entrez PY - 2013/11/8/pubmed PY - 2014/10/21/medline SP - 321 EP - 33 JF - Diabetologia JO - Diabetologia VL - 57 IS - 2 N2 - AIMS/HYPOTHESIS: Few studies have investigated the relationship between predefined dietary patterns and type 2 diabetes incidence; little is known about the generalisability of these associations. We aimed to assess the association between predefined dietary patterns and type 2 diabetes risk in European populations. METHODS: From among a case-cohort of 12,403 incident diabetes cases and 16,154 subcohort members nested within the prospective European Prospective Investigation into Cancer and Nutrition study, we used data on 9,682 cases and 12,595 subcohort participants from seven countries. Habitual dietary intake was assessed at baseline with country-specific dietary questionnaires. Two diet-quality scores (alternative Healthy Eating Index [aHEI], Dietary Approaches to Stop Hypertension [DASH] score) and three reduced rank regression (RRR)-derived dietary-pattern scores were constructed. Country-specific HRs were calculated and combined using a random-effects meta-analysis. RESULTS: After multivariable adjustment, including body size, the aHEI and DASH scores were not significantly associated with diabetes, although for the aHEI there was a tendency towards an inverse association in countries with higher mean age. We observed inverse associations of the three RRR-derived dietary-pattern scores with diabetes: HRs (95% CIs) for a 1-SD difference were 0.91 (0.86, 0.96), 0.92 (0.84, 1.01) and 0.87 (0.82, 0.92). Random-effects meta-analyses revealed heterogeneity between countries that was explainable by differences in the age of participants or the distribution of dietary intake. CONCLUSIONS/INTERPRETATION: Adherence to specific RRR-derived dietary patterns, commonly characterised by high intake of fruits or vegetables and low intake of processed meat, sugar-sweetened beverages and refined grains, may lower type 2 diabetes risk. SN - 1432-0428 UR - https://www.unboundmedicine.com/medline/citation/24196190/Adherence_to_predefined_dietary_patterns_and_incident_type_2_diabetes_in_European_populations:_EPIC_InterAct_Study_ L2 - https://dx.doi.org/10.1007/s00125-013-3092-9 DB - PRIME DP - Unbound Medicine ER -