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Comparing the effects of meal replacements with reduced-fat diet on weight, sexual and endothelial function, testosterone and quality of life in obese Asian men.
Int J Impot Res 2014 Mar-Apr; 26(2):61-6IJ

Abstract

Sexual dysfunction is more prevalent in obese than in normal-weight men. Meal replacements (MRs) are useful weight-loss strategies. We randomized obese (body mass index 27.5 kg m(-2), waist circumference (WC) 90 cm) Asian men (mean age 40.5 years, range 30-61) to a conventional reduced-fat diet (CD) (n=24) or MR-based plan (n=24) to reduce daily intake by 400 kcal for 12 weeks. There were significantly greater reductions in weight (4.2 ± 0.8 kg), WC (4.6 ± 0.7 cm), calorie and fat intake in the MR group, compared with the CD group (2.5 ± 0.4 kg, 2.6 ± 0.5 cm). Erectile function (International Index of Erectile Function 5-item score) improved comparably in the MR (3.4 ± 0.7 points) and CD (2.5 ± 0.5 points) groups, as did the Sexual Desire Inventory score (5.5 ± 2.3 vs 7.7 ± 2.1 points), quality of life (36-item Short Form survey score), plasma testosterone and endothelial function (Reactive Hyperemia Index). Subjects were switched to or continued CD for another 28 weeks. Weight, WC and erectile function were maintained at 40 weeks. MR induces greater reductions in weight and abdominal obesity than conventional diet, and comparable improvements in sexual and endothelial function, testosterone and quality of life.

Authors+Show Affiliations

Department of Endocrinology, Changi General Hospital, Singapore, Singapore.Department of Dietetic and Food Services, Changi General Hospital, Singapore, Singapore.Department of Dietetic and Food Services, Changi General Hospital, Singapore, Singapore.Department of Dietetic and Food Services, Changi General Hospital, Singapore, Singapore.Department of Dietetic and Food Services, Changi General Hospital, Singapore, Singapore.Department of Endocrinology, Changi General Hospital, Singapore, Singapore.Department of Endocrinology, Changi General Hospital, Singapore, Singapore.Department of Endocrinology, Changi General Hospital, Singapore, Singapore.Department of Dietetic and Food Services, Changi General Hospital, Singapore, Singapore.

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24196274

Citation

Khoo, J, et al. "Comparing the Effects of Meal Replacements With Reduced-fat Diet On Weight, Sexual and Endothelial Function, Testosterone and Quality of Life in Obese Asian Men." International Journal of Impotence Research, vol. 26, no. 2, 2014, pp. 61-6.
Khoo J, Ling PS, Tan J, et al. Comparing the effects of meal replacements with reduced-fat diet on weight, sexual and endothelial function, testosterone and quality of life in obese Asian men. Int J Impot Res. 2014;26(2):61-6.
Khoo, J., Ling, P. S., Tan, J., Teo, A., Ng, H. L., Chen, R. Y., ... Cheong, M. (2014). Comparing the effects of meal replacements with reduced-fat diet on weight, sexual and endothelial function, testosterone and quality of life in obese Asian men. International Journal of Impotence Research, 26(2), pp. 61-6. doi:10.1038/ijir.2013.36.
Khoo J, et al. Comparing the Effects of Meal Replacements With Reduced-fat Diet On Weight, Sexual and Endothelial Function, Testosterone and Quality of Life in Obese Asian Men. Int J Impot Res. 2014;26(2):61-6. PubMed PMID: 24196274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparing the effects of meal replacements with reduced-fat diet on weight, sexual and endothelial function, testosterone and quality of life in obese Asian men. AU - Khoo,J, AU - Ling,P-S, AU - Tan,J, AU - Teo,A, AU - Ng,H-L, AU - Chen,R Y-T, AU - Tay,T-L, AU - Tan,E, AU - Cheong,M, Y1 - 2013/11/07/ PY - 2013/04/05/received PY - 2013/08/23/revised PY - 2013/09/23/accepted PY - 2013/11/8/entrez PY - 2013/11/8/pubmed PY - 2014/11/15/medline SP - 61 EP - 6 JF - International journal of impotence research JO - Int. J. Impot. Res. VL - 26 IS - 2 N2 - Sexual dysfunction is more prevalent in obese than in normal-weight men. Meal replacements (MRs) are useful weight-loss strategies. We randomized obese (body mass index 27.5 kg m(-2), waist circumference (WC) 90 cm) Asian men (mean age 40.5 years, range 30-61) to a conventional reduced-fat diet (CD) (n=24) or MR-based plan (n=24) to reduce daily intake by 400 kcal for 12 weeks. There were significantly greater reductions in weight (4.2 ± 0.8 kg), WC (4.6 ± 0.7 cm), calorie and fat intake in the MR group, compared with the CD group (2.5 ± 0.4 kg, 2.6 ± 0.5 cm). Erectile function (International Index of Erectile Function 5-item score) improved comparably in the MR (3.4 ± 0.7 points) and CD (2.5 ± 0.5 points) groups, as did the Sexual Desire Inventory score (5.5 ± 2.3 vs 7.7 ± 2.1 points), quality of life (36-item Short Form survey score), plasma testosterone and endothelial function (Reactive Hyperemia Index). Subjects were switched to or continued CD for another 28 weeks. Weight, WC and erectile function were maintained at 40 weeks. MR induces greater reductions in weight and abdominal obesity than conventional diet, and comparable improvements in sexual and endothelial function, testosterone and quality of life. SN - 1476-5489 UR - https://www.unboundmedicine.com/medline/citation/24196274/full_citation L2 - http://dx.doi.org/10.1038/ijir.2013.36 DB - PRIME DP - Unbound Medicine ER -