Tags

Type your tag names separated by a space and hit enter

Prospective evaluation of office-based injection laryngoplasty with hyaluronic acid gel.
Ann Otol Rhinol Laryngol. 2013 Sep; 122(9):541-6.AO

Abstract

OBJECTIVES

The role of Juvederm Ultra Plus hyaluronic acid gel for use in injection laryngoplasty has not been well examined. The aim of this study was to prospectively assess the safety and clinical effectiveness of office-based injection laryngoplasty of Juvederm Ultra Plus gel in patients with glottic insufficiency.

METHODS

Thirty patients met the criteria for study inclusion and were treated with unsedated office-based injection laryngoplasty of Juvederm Ultra Plus gel over a 20-month period. The preinjection acoustic and aerodynamic measures, Voice Handicap Index, Glottal Function Index, and Dysphonia Severity Index were compared with values recorded at 1 and 4 months after injection.

RESULTS

Data for 27 patients were available for follow-up analysis at 1 month, and 12 patients' data were available at 4 months. Significant improvements, compared to preinjection levels (p < 0.02), were shown in all outcome measures at 1 and 4 months. One patient required intravenous steroid therapy for delayed glottic inflammation that resolved without permanent sequelae.

CONCLUSIONS

The injection of Juvederm Ultra Plus gel is a relatively safe procedure that allows for short-term improvements in objective and subjective outcome measures of vocal function in patients with glottic insufficiency, provided the surgeon remains alert to the possibility of postprocedural injection site inflammation.

Authors+Show Affiliations

Department of Surgery, Division of Otolaryngology, University of Wisconsin Hospital and Clinics, Madison, Wisconsin 53792, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

24224395

Citation

Upton, David C., et al. "Prospective Evaluation of Office-based Injection Laryngoplasty With Hyaluronic Acid Gel." The Annals of Otology, Rhinology, and Laryngology, vol. 122, no. 9, 2013, pp. 541-6.
Upton DC, Johnson M, Zelazny SK, et al. Prospective evaluation of office-based injection laryngoplasty with hyaluronic acid gel. Ann Otol Rhinol Laryngol. 2013;122(9):541-6.
Upton, D. C., Johnson, M., Zelazny, S. K., & Dailey, S. H. (2013). Prospective evaluation of office-based injection laryngoplasty with hyaluronic acid gel. The Annals of Otology, Rhinology, and Laryngology, 122(9), 541-6.
Upton DC, et al. Prospective Evaluation of Office-based Injection Laryngoplasty With Hyaluronic Acid Gel. Ann Otol Rhinol Laryngol. 2013;122(9):541-6. PubMed PMID: 24224395.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prospective evaluation of office-based injection laryngoplasty with hyaluronic acid gel. AU - Upton,David C, AU - Johnson,Matthew, AU - Zelazny,Sherri K, AU - Dailey,Seth H, PY - 2013/11/15/entrez PY - 2013/11/15/pubmed PY - 2013/12/16/medline SP - 541 EP - 6 JF - The Annals of otology, rhinology, and laryngology JO - Ann. Otol. Rhinol. Laryngol. VL - 122 IS - 9 N2 - OBJECTIVES: The role of Juvederm Ultra Plus hyaluronic acid gel for use in injection laryngoplasty has not been well examined. The aim of this study was to prospectively assess the safety and clinical effectiveness of office-based injection laryngoplasty of Juvederm Ultra Plus gel in patients with glottic insufficiency. METHODS: Thirty patients met the criteria for study inclusion and were treated with unsedated office-based injection laryngoplasty of Juvederm Ultra Plus gel over a 20-month period. The preinjection acoustic and aerodynamic measures, Voice Handicap Index, Glottal Function Index, and Dysphonia Severity Index were compared with values recorded at 1 and 4 months after injection. RESULTS: Data for 27 patients were available for follow-up analysis at 1 month, and 12 patients' data were available at 4 months. Significant improvements, compared to preinjection levels (p < 0.02), were shown in all outcome measures at 1 and 4 months. One patient required intravenous steroid therapy for delayed glottic inflammation that resolved without permanent sequelae. CONCLUSIONS: The injection of Juvederm Ultra Plus gel is a relatively safe procedure that allows for short-term improvements in objective and subjective outcome measures of vocal function in patients with glottic insufficiency, provided the surgeon remains alert to the possibility of postprocedural injection site inflammation. SN - 0003-4894 UR - https://www.unboundmedicine.com/medline/citation/24224395/Prospective_evaluation_of_office_based_injection_laryngoplasty_with_hyaluronic_acid_gel_ L2 - http://journals.sagepub.com/doi/full/10.1177/000348941312200901?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -