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The inhibition by azatadine of the immunological release of leukotrienes and histamine from human lung fragments.
Eur J Pharmacol. 1986 Apr 29; 123(3):463-5.EJ

Abstract

The effects of the H1 antihistamine azatadine on the antigen-induced release of slow reacting substance of anaphylaxis (leukotrienes C4 and D4) and histamine from passively sensitized human lung fragments were determined. Azatadine 0.1-10 microM significantly and dose dependently inhibited the release of leukotrienes from lung by 22-71%. Histamine release was also inhibited by azatadine 10 microM.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2424773

Citation

Daniels, C, and D M. Temple. "The Inhibition By Azatadine of the Immunological Release of Leukotrienes and Histamine From Human Lung Fragments." European Journal of Pharmacology, vol. 123, no. 3, 1986, pp. 463-5.
Daniels C, Temple DM. The inhibition by azatadine of the immunological release of leukotrienes and histamine from human lung fragments. Eur J Pharmacol. 1986;123(3):463-5.
Daniels, C., & Temple, D. M. (1986). The inhibition by azatadine of the immunological release of leukotrienes and histamine from human lung fragments. European Journal of Pharmacology, 123(3), 463-5.
Daniels C, Temple DM. The Inhibition By Azatadine of the Immunological Release of Leukotrienes and Histamine From Human Lung Fragments. Eur J Pharmacol. 1986 Apr 29;123(3):463-5. PubMed PMID: 2424773.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The inhibition by azatadine of the immunological release of leukotrienes and histamine from human lung fragments. AU - Daniels,C, AU - Temple,D M, PY - 1986/4/29/pubmed PY - 1986/4/29/medline PY - 1986/4/29/entrez SP - 463 EP - 5 JF - European journal of pharmacology JO - Eur J Pharmacol VL - 123 IS - 3 N2 - The effects of the H1 antihistamine azatadine on the antigen-induced release of slow reacting substance of anaphylaxis (leukotrienes C4 and D4) and histamine from passively sensitized human lung fragments were determined. Azatadine 0.1-10 microM significantly and dose dependently inhibited the release of leukotrienes from lung by 22-71%. Histamine release was also inhibited by azatadine 10 microM. SN - 0014-2999 UR - https://www.unboundmedicine.com/medline/citation/2424773/The_inhibition_by_azatadine_of_the_immunological_release_of_leukotrienes_and_histamine_from_human_lung_fragments_ DB - PRIME DP - Unbound Medicine ER -
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