Tags

Type your tag names separated by a space and hit enter

New developments in diagnosis and non-surgical treatment of chronic pancreatitis.
J Gastroenterol Hepatol. 2013 Dec; 28 Suppl 4:108-12.JG

Abstract

Chronic pancreatitis is progressive and irreversible, leading to digestive and absorptive disorders by destruction of the exocrine pancreas and to diabetes mellitus by destruction of the endocrine pancreas. When complications such as pancreatolithiasis and pseudocyst occur, elevated pancreatic ductal pressure exacerbates pain and induces other complications, worsening the patient's general condition. Combined treatment with extracorporeal shock-wave lithotripsy and endoscopic lithotripsy is a useful, minimally invasive, first-line treatment approach that can preserve pancreatic exocrine function. Pancreatic duct stenosis elevates intraductal pressure and favor both pancreatolithiasis and pseudocyst formation, making effective treatment vitally important. Endoscopic treatment of benign pancreatic duct stenosis stenting frequently decreases pain in chronic pancreatitis. Importantly, stenosis of the main pancreatic duct increases risk of stone recurrence after treatment of pancreatolithiasis. Recently, good results were reported in treating pancreatic duct stricture with a fully covered self-expandable metallic stent, which shows promise for preventing stone recurrence after lithotripsy in patients with pancreatic stricture. Chronic pancreatitis has many complications including pancreatic carcinoma, pancreatic atrophy, and loss of exocrine and endocrine function, as well as frequent recurrence of stones after treatment of pancreatolithiasis. As early treatment of chronic pancreatitis is essential, the new concept of early chronic pancreatitis, including characteristics findings in endoscopic ultrasonograms, is presented.

Authors+Show Affiliations

Department of Gastroenterology, Second Teaching Hospital, Fujita Health University School of Medicine, Nakagawa-ku, Nagoya, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

24251715

Citation

Inui, Kazuo, et al. "New Developments in Diagnosis and Non-surgical Treatment of Chronic Pancreatitis." Journal of Gastroenterology and Hepatology, vol. 28 Suppl 4, 2013, pp. 108-12.
Inui K, Yoshino J, Miyoshi H, et al. New developments in diagnosis and non-surgical treatment of chronic pancreatitis. J Gastroenterol Hepatol. 2013;28 Suppl 4:108-12.
Inui, K., Yoshino, J., Miyoshi, H., Yamamoto, S., & Kobayashi, T. (2013). New developments in diagnosis and non-surgical treatment of chronic pancreatitis. Journal of Gastroenterology and Hepatology, 28 Suppl 4, 108-12. https://doi.org/10.1111/jgh.12250
Inui K, et al. New Developments in Diagnosis and Non-surgical Treatment of Chronic Pancreatitis. J Gastroenterol Hepatol. 2013;28 Suppl 4:108-12. PubMed PMID: 24251715.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New developments in diagnosis and non-surgical treatment of chronic pancreatitis. AU - Inui,Kazuo, AU - Yoshino,Junji, AU - Miyoshi,Hironao, AU - Yamamoto,Satoshi, AU - Kobayashi,Takashi, PY - 2013/03/04/accepted PY - 2013/11/21/entrez PY - 2013/11/28/pubmed PY - 2014/10/3/medline KW - early chronic pancreatitis KW - extracorporeal shock-wave lithotripsy KW - pancreatic ductal stricture KW - pancreatic exocrine function KW - pancreatolithiasis SP - 108 EP - 12 JF - Journal of gastroenterology and hepatology JO - J. Gastroenterol. Hepatol. VL - 28 Suppl 4 N2 - Chronic pancreatitis is progressive and irreversible, leading to digestive and absorptive disorders by destruction of the exocrine pancreas and to diabetes mellitus by destruction of the endocrine pancreas. When complications such as pancreatolithiasis and pseudocyst occur, elevated pancreatic ductal pressure exacerbates pain and induces other complications, worsening the patient's general condition. Combined treatment with extracorporeal shock-wave lithotripsy and endoscopic lithotripsy is a useful, minimally invasive, first-line treatment approach that can preserve pancreatic exocrine function. Pancreatic duct stenosis elevates intraductal pressure and favor both pancreatolithiasis and pseudocyst formation, making effective treatment vitally important. Endoscopic treatment of benign pancreatic duct stenosis stenting frequently decreases pain in chronic pancreatitis. Importantly, stenosis of the main pancreatic duct increases risk of stone recurrence after treatment of pancreatolithiasis. Recently, good results were reported in treating pancreatic duct stricture with a fully covered self-expandable metallic stent, which shows promise for preventing stone recurrence after lithotripsy in patients with pancreatic stricture. Chronic pancreatitis has many complications including pancreatic carcinoma, pancreatic atrophy, and loss of exocrine and endocrine function, as well as frequent recurrence of stones after treatment of pancreatolithiasis. As early treatment of chronic pancreatitis is essential, the new concept of early chronic pancreatitis, including characteristics findings in endoscopic ultrasonograms, is presented. SN - 1440-1746 UR - https://www.unboundmedicine.com/medline/citation/24251715/New_developments_in_diagnosis_and_non_surgical_treatment_of_chronic_pancreatitis_ L2 - https://doi.org/10.1111/jgh.12250 DB - PRIME DP - Unbound Medicine ER -