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Benign metastasizing leiomyoma presenting as cavitating lung nodules.
Respir Care. 2014 Jul; 59(7):e94-7.RC

Abstract

Benign metastasizing leiomyoma (BML) was initially used to describe single or multiple pulmonary nodules composed of proliferating smooth muscle cells (lacking cellular atypia) in premenopausal females 3 months to 20 y after hysterectomy for uterine leiomyoma. The lung is the most commonly involved site, thus including many malignant and benign entities in the differential diagnosis. The present case refers to a 47-y-old premenopausal woman with a history of subtotal hysterectomy for a uterine leiomyoma presenting with bilateral cavitating pulmonary nodules. A number of nodules were resected by video-assisted thoracoscopic surgery. The histological findings in correlation with the immunohistochemical results were consistent with the diagnosis of BML. A bilateral salpingo-oophorectomy was performed, combined with complete removal of the remaining cervix. One year later, the subject remains asymptomatic, and the pulmonary nodules are stable with regard to number, size, location, and morphology.

Authors+Show Affiliations

Respiratory Intensive Care Unit angelouk@live.com.12th Respiratory Medicine Department.Pathology Department, Athens Chest Hospital "Sotiria," Athens, Greece.12th Respiratory Medicine Department.Pathology Department, Athens Chest Hospital "Sotiria," Athens, Greece.1st Paediatric Clinic, "Aghia Sophia" Children's Hospital, National and Kapodistrian University of Athens Medical School, Athens, Greece.12th Respiratory Medicine Department.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

24255161

Citation

Loukeri, Angeliki A., et al. "Benign Metastasizing Leiomyoma Presenting as Cavitating Lung Nodules." Respiratory Care, vol. 59, no. 7, 2014, pp. e94-7.
Loukeri AA, Pantazopoulos IN, Tringidou R, et al. Benign metastasizing leiomyoma presenting as cavitating lung nodules. Respir Care. 2014;59(7):e94-7.
Loukeri, A. A., Pantazopoulos, I. N., Tringidou, R., Giampoudakis, P., Valaskatzi, A., Loukeri, P. A., & Kampolis, C. F. (2014). Benign metastasizing leiomyoma presenting as cavitating lung nodules. Respiratory Care, 59(7), e94-7. https://doi.org/10.4187/respcare.02775
Loukeri AA, et al. Benign Metastasizing Leiomyoma Presenting as Cavitating Lung Nodules. Respir Care. 2014;59(7):e94-7. PubMed PMID: 24255161.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Benign metastasizing leiomyoma presenting as cavitating lung nodules. AU - Loukeri,Angeliki A, AU - Pantazopoulos,Ioannis N, AU - Tringidou,Rodoula, AU - Giampoudakis,Pantelis, AU - Valaskatzi,Argyro, AU - Loukeri,Pinelopi A, AU - Kampolis,Christos F, Y1 - 2013/11/19/ PY - 2013/11/21/entrez PY - 2013/11/21/pubmed PY - 2015/7/15/medline KW - benign KW - cavitary KW - hysterectomy KW - premenopause KW - pulmonary nodules KW - uterine leiomyoma SP - e94 EP - 7 JF - Respiratory care JO - Respir Care VL - 59 IS - 7 N2 - Benign metastasizing leiomyoma (BML) was initially used to describe single or multiple pulmonary nodules composed of proliferating smooth muscle cells (lacking cellular atypia) in premenopausal females 3 months to 20 y after hysterectomy for uterine leiomyoma. The lung is the most commonly involved site, thus including many malignant and benign entities in the differential diagnosis. The present case refers to a 47-y-old premenopausal woman with a history of subtotal hysterectomy for a uterine leiomyoma presenting with bilateral cavitating pulmonary nodules. A number of nodules were resected by video-assisted thoracoscopic surgery. The histological findings in correlation with the immunohistochemical results were consistent with the diagnosis of BML. A bilateral salpingo-oophorectomy was performed, combined with complete removal of the remaining cervix. One year later, the subject remains asymptomatic, and the pulmonary nodules are stable with regard to number, size, location, and morphology. SN - 1943-3654 UR - https://www.unboundmedicine.com/medline/citation/24255161/Benign_metastasizing_leiomyoma_presenting_as_cavitating_lung_nodules_ L2 - http://rc.rcjournal.com/cgi/pmidlookup?view=short&pmid=24255161 DB - PRIME DP - Unbound Medicine ER -