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Evaluation of highly accelerated real-time cardiac cine MRI in tachycardia.
NMR Biomed 2014; 27(2):175-82NB

Abstract

Electrocardiogram (ECG)-gated breath-hold cine MRI is considered to be the gold standard test for the assessment of cardiac function. However, it may fail in patients with arrhythmia, impaired breath-hold capacity and poor ECG gating. Although ungated real-time cine MRI may mitigate these problems, commercially available real-time cine MRI pulse sequences using parallel imaging typically yield relatively poor spatiotemporal resolution because of their low image acquisition efficiency. As an extension of our previous work, the purpose of this study was to evaluate the diagnostic quality and accuracy of eight-fold-accelerated real-time cine MRI with compressed sensing (CS) for the quantification of cardiac function in tachycardia, where it is challenging for real-time cine MRI to provide sufficient spatiotemporal resolution. We evaluated the performances of eight-fold-accelerated cine MRI with CS, three-fold-accelerated real-time cine MRI with temporal generalized autocalibrating partially parallel acquisitions (TGRAPPA) and ECG-gated breath-hold cine MRI in 21 large animals with tachycardia (mean heart rate, 104 beats per minute) at 3T. For each cine MRI method, two expert readers evaluated the diagnostic quality in four categories (image quality, temporal fidelity of wall motion, artifacts and apparent noise) using a Likert scale (1-5, worst to best). One reader evaluated the left ventricular functional parameters. The diagnostic quality scores were significantly different between the three cine pulse sequences, except for the artifact level between CS and TGRAPPA real-time cine MRI. Both ECG-gated breath-hold cine MRI and eight-fold accelerated real-time cine MRI yielded all four scores of ≥ 3.0 (acceptable), whereas three-fold-accelerated real-time cine MRI yielded all scores below 3.0, except for artifact (3.0). The left ventricular ejection fraction (LVEF) measurements agreed better between ECG-gated cine MRI and eight-fold-accelerated real-time cine MRI (mean difference, -1.6%) than between ECG-gated cine MRI and three-fold-accelerated real-time cine MRI (mean difference, -5.7%). Eight-fold-accelerated real-time cine MRI with CS yields acceptable diagnostic quality and relatively accurate LVEF measurements in the challenging setting of tachycardia.

Authors+Show Affiliations

Department of Physics, University of Utah, Salt Lake City, UT, USA; UCAIR, Department of Radiology, University of Utah, Salt Lake City, UT, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24259281

Citation

Bassett, Elwin C., et al. "Evaluation of Highly Accelerated Real-time Cardiac Cine MRI in Tachycardia." NMR in Biomedicine, vol. 27, no. 2, 2014, pp. 175-82.
Bassett EC, Kholmovski EG, Wilson BD, et al. Evaluation of highly accelerated real-time cardiac cine MRI in tachycardia. NMR Biomed. 2014;27(2):175-82.
Bassett, E. C., Kholmovski, E. G., Wilson, B. D., DiBella, E. V., Dosdall, D. J., Ranjan, R., ... Kim, D. (2014). Evaluation of highly accelerated real-time cardiac cine MRI in tachycardia. NMR in Biomedicine, 27(2), pp. 175-82. doi:10.1002/nbm.3049.
Bassett EC, et al. Evaluation of Highly Accelerated Real-time Cardiac Cine MRI in Tachycardia. NMR Biomed. 2014;27(2):175-82. PubMed PMID: 24259281.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of highly accelerated real-time cardiac cine MRI in tachycardia. AU - Bassett,Elwin C, AU - Kholmovski,Eugene G, AU - Wilson,Brent D, AU - DiBella,Edward V R, AU - Dosdall,Derek J, AU - Ranjan,Ravi, AU - McGann,Christopher J, AU - Kim,Daniel, Y1 - 2013/11/21/ PY - 2013/05/16/received PY - 2013/10/08/revised PY - 2013/10/10/accepted PY - 2013/11/22/entrez PY - 2013/11/22/pubmed PY - 2014/10/25/medline KW - cardiac function KW - compressed sensing KW - heart KW - real-time cine MRI KW - tachycardia SP - 175 EP - 82 JF - NMR in biomedicine JO - NMR Biomed VL - 27 IS - 2 N2 - Electrocardiogram (ECG)-gated breath-hold cine MRI is considered to be the gold standard test for the assessment of cardiac function. However, it may fail in patients with arrhythmia, impaired breath-hold capacity and poor ECG gating. Although ungated real-time cine MRI may mitigate these problems, commercially available real-time cine MRI pulse sequences using parallel imaging typically yield relatively poor spatiotemporal resolution because of their low image acquisition efficiency. As an extension of our previous work, the purpose of this study was to evaluate the diagnostic quality and accuracy of eight-fold-accelerated real-time cine MRI with compressed sensing (CS) for the quantification of cardiac function in tachycardia, where it is challenging for real-time cine MRI to provide sufficient spatiotemporal resolution. We evaluated the performances of eight-fold-accelerated cine MRI with CS, three-fold-accelerated real-time cine MRI with temporal generalized autocalibrating partially parallel acquisitions (TGRAPPA) and ECG-gated breath-hold cine MRI in 21 large animals with tachycardia (mean heart rate, 104 beats per minute) at 3T. For each cine MRI method, two expert readers evaluated the diagnostic quality in four categories (image quality, temporal fidelity of wall motion, artifacts and apparent noise) using a Likert scale (1-5, worst to best). One reader evaluated the left ventricular functional parameters. The diagnostic quality scores were significantly different between the three cine pulse sequences, except for the artifact level between CS and TGRAPPA real-time cine MRI. Both ECG-gated breath-hold cine MRI and eight-fold accelerated real-time cine MRI yielded all four scores of ≥ 3.0 (acceptable), whereas three-fold-accelerated real-time cine MRI yielded all scores below 3.0, except for artifact (3.0). The left ventricular ejection fraction (LVEF) measurements agreed better between ECG-gated cine MRI and eight-fold-accelerated real-time cine MRI (mean difference, -1.6%) than between ECG-gated cine MRI and three-fold-accelerated real-time cine MRI (mean difference, -5.7%). Eight-fold-accelerated real-time cine MRI with CS yields acceptable diagnostic quality and relatively accurate LVEF measurements in the challenging setting of tachycardia. SN - 1099-1492 UR - https://www.unboundmedicine.com/medline/citation/24259281/Evaluation_of_highly_accelerated_real_time_cardiac_cine_MRI_in_tachycardia_ L2 - https://doi.org/10.1002/nbm.3049 DB - PRIME DP - Unbound Medicine ER -