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Mediterranean diet and cardiovascular risk factors: a systematic review.

Abstract

The aim of this paper was to systematically review and analyze the epidemiological evidence on the role of Mediterranean diet (MD) in the prevention of cardiovascular diseases (CVD). Fifty-eight studies exploring the relation between MD and lipoprotein concentration, antioxidative capacity and inflammatory markers, hypertension, obesity, diabetes, and metabolic syndrome, were identified and selected. These included 33 cross-sectional, 9 cohort, and 16 intervention studies. Most of the studies showed favorable effects of MD on CVD, although a certain degree of controversy remains in the respect of some issues, as obesity. Important methodological differences and limitations in the studies make difficult to compare results, thus further studies, particularly randomized clinical trials, are needed to finally substantiate the benefits of MD and to shed some lights on mechanisms.

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  • Authors+Show Affiliations

    ,

    a Department "G. F. Ingrassia," Section of Hygiene and Public Health , University of Catania , Catania , Italy.

    , , , , , , ,

    Source

    MeSH

    Biomarkers
    Cardiovascular Diseases
    Diet, Mediterranean
    Humans
    Metabolic Syndrome
    Obesity
    Observational Studies as Topic
    Randomized Controlled Trials as Topic
    Risk Factors

    Pub Type(s)

    Journal Article
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    24261534

    Citation

    Grosso, Giuseppe, et al. "Mediterranean Diet and Cardiovascular Risk Factors: a Systematic Review." Critical Reviews in Food Science and Nutrition, vol. 54, no. 5, 2014, pp. 593-610.
    Grosso G, Mistretta A, Frigiola A, et al. Mediterranean diet and cardiovascular risk factors: a systematic review. Crit Rev Food Sci Nutr. 2014;54(5):593-610.
    Grosso, G., Mistretta, A., Frigiola, A., Gruttadauria, S., Biondi, A., Basile, F., ... Galvano, F. (2014). Mediterranean diet and cardiovascular risk factors: a systematic review. Critical Reviews in Food Science and Nutrition, 54(5), pp. 593-610. doi:10.1080/10408398.2011.596955.
    Grosso G, et al. Mediterranean Diet and Cardiovascular Risk Factors: a Systematic Review. Crit Rev Food Sci Nutr. 2014;54(5):593-610. PubMed PMID: 24261534.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Mediterranean diet and cardiovascular risk factors: a systematic review. AU - Grosso,Giuseppe, AU - Mistretta,Antonio, AU - Frigiola,Alessandro, AU - Gruttadauria,Salvatore, AU - Biondi,Antonio, AU - Basile,Francesco, AU - Vitaglione,Paola, AU - D'Orazio,Nicolantonio, AU - Galvano,Fabio, PY - 2013/11/23/entrez PY - 2013/11/23/pubmed PY - 2014/7/10/medline SP - 593 EP - 610 JF - Critical reviews in food science and nutrition JO - Crit Rev Food Sci Nutr VL - 54 IS - 5 N2 - The aim of this paper was to systematically review and analyze the epidemiological evidence on the role of Mediterranean diet (MD) in the prevention of cardiovascular diseases (CVD). Fifty-eight studies exploring the relation between MD and lipoprotein concentration, antioxidative capacity and inflammatory markers, hypertension, obesity, diabetes, and metabolic syndrome, were identified and selected. These included 33 cross-sectional, 9 cohort, and 16 intervention studies. Most of the studies showed favorable effects of MD on CVD, although a certain degree of controversy remains in the respect of some issues, as obesity. Important methodological differences and limitations in the studies make difficult to compare results, thus further studies, particularly randomized clinical trials, are needed to finally substantiate the benefits of MD and to shed some lights on mechanisms. SN - 1549-7852 UR - https://www.unboundmedicine.com/medline/citation/24261534/Mediterranean_diet_and_cardiovascular_risk_factors:_a_systematic_review_ L2 - http://www.tandfonline.com/doi/full/10.1080/10408398.2011.596955 DB - PRIME DP - Unbound Medicine ER -