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[The predictive value of admission hyperglycemia in hospital and long-term mortality of diabetics versus non-diabetics with acute coronary syndrome].
Zhonghua Nei Ke Za Zhi 2013; 52(7):570-3ZN

Abstract

OBJECTIVE

To evaluate whether the predictive value of admission hyperglycemia for mortality differs between diabetics and non-diabetics with acute coronary syndrome (ACS).

METHODS

A total of 1534 consecutive patients admitted with ACS to Central Control Unit of Beijing Friendship Hospital were analyzed. Among these patients, 1332 patients who had a venous plasma glucose record at admission were retrospectively enrolled and were stratified according to admission glucose levels with or without diabetes. The primary end point was in-hospital and 2-year all-cause mortality.

RESULTS

In patients without a history of diabetes, 649 patients had glucose level ≤ 7.8 mmol/L(group A), 204 patients with 7.8-11.0 mmol/L (group B) and 142 patients > 11.0 mmol/L (group C). Of those with diabetes, 124 patients were in group A, 142 in group B and 126 in group C. By Cox regression analysis, admission hyperglycemia (group B, HR 1.48, P = 0.05; group C, HR 2.78, P < 0.001) was an independent predictor of long-term all-cause mortality in patients without diabetes. In patients with diabetes, blood glucose > 11.0 mmol/L (group C, HR 2.68, P < 0.001) also independently predicted long-term all-cause mortality.

CONCLUSIONS

Compared with the diabetic patients, elevation of blood glucose at admission is common in ACS patients without definite history of diabetes. Admission hyperglycemia should be considered as a risk factor strongly correlated with in-hospital and 2-year all-cause mortality in patients with ACS.

Authors+Show Affiliations

Department of Cardiology, Beijing Friendship Hospital, Capital Medical University,Beijing 100050, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

24266998

Citation

Song, Hui-fen, et al. "[The Predictive Value of Admission Hyperglycemia in Hospital and Long-term Mortality of Diabetics Versus Non-diabetics With Acute Coronary Syndrome]." Zhonghua Nei Ke Za Zhi, vol. 52, no. 7, 2013, pp. 570-3.
Song HF, Li HW, Zhao SM, et al. [The predictive value of admission hyperglycemia in hospital and long-term mortality of diabetics versus non-diabetics with acute coronary syndrome]. Zhonghua Nei Ke Za Zhi. 2013;52(7):570-3.
Song, H. F., Li, H. W., Zhao, S. M., Wang, S., & Li, X. H. (2013). [The predictive value of admission hyperglycemia in hospital and long-term mortality of diabetics versus non-diabetics with acute coronary syndrome]. Zhonghua Nei Ke Za Zhi, 52(7), pp. 570-3.
Song HF, et al. [The Predictive Value of Admission Hyperglycemia in Hospital and Long-term Mortality of Diabetics Versus Non-diabetics With Acute Coronary Syndrome]. Zhonghua Nei Ke Za Zhi. 2013;52(7):570-3. PubMed PMID: 24266998.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The predictive value of admission hyperglycemia in hospital and long-term mortality of diabetics versus non-diabetics with acute coronary syndrome]. AU - Song,Hui-fen, AU - Li,Hong-wei, AU - Zhao,Shu-me, AU - Wang,Su, AU - Li,Xiao-hui, PY - 2013/11/26/entrez PY - 2013/11/26/pubmed PY - 2014/4/18/medline SP - 570 EP - 3 JF - Zhonghua nei ke za zhi JO - Zhonghua Nei Ke Za Zhi VL - 52 IS - 7 N2 - OBJECTIVE: To evaluate whether the predictive value of admission hyperglycemia for mortality differs between diabetics and non-diabetics with acute coronary syndrome (ACS). METHODS: A total of 1534 consecutive patients admitted with ACS to Central Control Unit of Beijing Friendship Hospital were analyzed. Among these patients, 1332 patients who had a venous plasma glucose record at admission were retrospectively enrolled and were stratified according to admission glucose levels with or without diabetes. The primary end point was in-hospital and 2-year all-cause mortality. RESULTS: In patients without a history of diabetes, 649 patients had glucose level ≤ 7.8 mmol/L(group A), 204 patients with 7.8-11.0 mmol/L (group B) and 142 patients > 11.0 mmol/L (group C). Of those with diabetes, 124 patients were in group A, 142 in group B and 126 in group C. By Cox regression analysis, admission hyperglycemia (group B, HR 1.48, P = 0.05; group C, HR 2.78, P < 0.001) was an independent predictor of long-term all-cause mortality in patients without diabetes. In patients with diabetes, blood glucose > 11.0 mmol/L (group C, HR 2.68, P < 0.001) also independently predicted long-term all-cause mortality. CONCLUSIONS: Compared with the diabetic patients, elevation of blood glucose at admission is common in ACS patients without definite history of diabetes. Admission hyperglycemia should be considered as a risk factor strongly correlated with in-hospital and 2-year all-cause mortality in patients with ACS. SN - 0578-1426 UR - https://www.unboundmedicine.com/medline/citation/24266998/[The_predictive_value_of_admission_hyperglycemia_in_hospital_and_long_term_mortality_of_diabetics_versus_non_diabetics_with_acute_coronary_syndrome]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0578-1426&amp;year=2013&amp;vol=52&amp;issue=7&amp;fpage=570 DB - PRIME DP - Unbound Medicine ER -