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Poly(vinyl alcohol)/cellulose nanowhiskers nanocomposite hydrogels for potential wound dressings.
Mater Sci Eng C Mater Biol Appl. 2014 Jan 01; 34:54-61.MS

Abstract

Polyvinyl alcohol (PVA)/cellulose nanowhisker (CNW) nanocomposite hydrogels to be used for wound dressing were obtained by freezing-thawing technique and characterized by means of morphological, physical, thermal, mechanical, barrier and antimicrobial properties. First, cellulose nanowhiskers were obtained by the acid hydrolysis of commercial crystalline microcellulose (MCC) and characterized by its size, shape, morphological, structural and thermal properties. Then, PVA/CNW nanocomposites with several CNW contents (0, 1, 3, 5 and 7wt.%) were obtained. Morphological, thermal, chemical and physical characterization of the PVA/CNW nanocomposite hydrogels was carried out. It was found that the addition of CNW to the hydrogel allows controlling the pore morphology of the samples. On the other hand, the transparency of the samples was maintained, the thermal stability was increased, the mechanical properties were improved and the water vapor transmission rate was in the range of wound dressing applications after CNW incorporation inside the PVA hydrogel matrix. The evaluation of microbial penetration showed that the prepared hydrogels can be considered as a good barrier against different microorganisms. All obtained results indicate that the PVA/CNW materials are promising to be used as wound dressing.

Authors+Show Affiliations

Composite Materials Group, Research Institute of Material Science and Technology (INTEMA) (CONICET-UNMdP), Solís 7575, B7608FLC Mar del Plata, Argentina.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24268233

Citation

Gonzalez, Jimena S., et al. "Poly(vinyl Alcohol)/cellulose Nanowhiskers Nanocomposite Hydrogels for Potential Wound Dressings." Materials Science & Engineering. C, Materials for Biological Applications, vol. 34, 2014, pp. 54-61.
Gonzalez JS, Ludueña LN, Ponce A, et al. Poly(vinyl alcohol)/cellulose nanowhiskers nanocomposite hydrogels for potential wound dressings. Mater Sci Eng C Mater Biol Appl. 2014;34:54-61.
Gonzalez, J. S., Ludueña, L. N., Ponce, A., & Alvarez, V. A. (2014). Poly(vinyl alcohol)/cellulose nanowhiskers nanocomposite hydrogels for potential wound dressings. Materials Science & Engineering. C, Materials for Biological Applications, 34, 54-61. https://doi.org/10.1016/j.msec.2013.10.006
Gonzalez JS, et al. Poly(vinyl Alcohol)/cellulose Nanowhiskers Nanocomposite Hydrogels for Potential Wound Dressings. Mater Sci Eng C Mater Biol Appl. 2014 Jan 1;34:54-61. PubMed PMID: 24268233.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Poly(vinyl alcohol)/cellulose nanowhiskers nanocomposite hydrogels for potential wound dressings. AU - Gonzalez,Jimena S, AU - Ludueña,Leandro N, AU - Ponce,Alejandra, AU - Alvarez,Vera A, Y1 - 2013/10/18/ PY - 2013/06/02/received PY - 2013/08/27/revised PY - 2013/10/10/accepted PY - 2013/11/26/entrez PY - 2013/11/26/pubmed PY - 2014/8/27/medline KW - Cellulose nanowhiskers KW - Composite hydrogel KW - Nano-composites KW - Nano-particles KW - Polymer-matrix composites SP - 54 EP - 61 JF - Materials science & engineering. C, Materials for biological applications JO - Mater Sci Eng C Mater Biol Appl VL - 34 N2 - Polyvinyl alcohol (PVA)/cellulose nanowhisker (CNW) nanocomposite hydrogels to be used for wound dressing were obtained by freezing-thawing technique and characterized by means of morphological, physical, thermal, mechanical, barrier and antimicrobial properties. First, cellulose nanowhiskers were obtained by the acid hydrolysis of commercial crystalline microcellulose (MCC) and characterized by its size, shape, morphological, structural and thermal properties. Then, PVA/CNW nanocomposites with several CNW contents (0, 1, 3, 5 and 7wt.%) were obtained. Morphological, thermal, chemical and physical characterization of the PVA/CNW nanocomposite hydrogels was carried out. It was found that the addition of CNW to the hydrogel allows controlling the pore morphology of the samples. On the other hand, the transparency of the samples was maintained, the thermal stability was increased, the mechanical properties were improved and the water vapor transmission rate was in the range of wound dressing applications after CNW incorporation inside the PVA hydrogel matrix. The evaluation of microbial penetration showed that the prepared hydrogels can be considered as a good barrier against different microorganisms. All obtained results indicate that the PVA/CNW materials are promising to be used as wound dressing. SN - 1873-0191 UR - https://www.unboundmedicine.com/medline/citation/24268233/Poly_vinyl_alcohol_/cellulose_nanowhiskers_nanocomposite_hydrogels_for_potential_wound_dressings_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0928-4931(13)00574-2 DB - PRIME DP - Unbound Medicine ER -