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Tracking blood lead and zinc protoporphyrin levels in Andean adults working in a lead contaminated environment.
J Toxicol Environ Health A. 2013; 76(19):1111-20.JT

Abstract

The purpose of this study was to investigate current blood lead (PbB) and zinc protoporphyrin (ZPP) levels in adults presently living in environmentally Pb-contaminated Andean communities, and to compare the findings with the PbB and ZPP levels of Pb-exposed adult cohorts from the same study area tested between 1996 and 2007. Blood samples from 39 adults were measured for PbB and ZPP concentrations. The current mean PbB level (22.7 μg/dl) was significantly lower than the mean (37.9 μg/dl) of the initial 1996 cohort. PbB levels for the 1997, 1998, 2003, and 2006 cohorts were also significantly lower than the levels for the 1996 group. Elevated ZPP/heme ratios of 103.3, 128.4, and 134.2 μmol/mol were not significantly different for the 2006, 2007, and 2012 groups, indicating chronic Pb exposure. While ZPP levels of Andean Ecuadorian Pb-glazing workers have remained elevated, PbB levels declined. Lead exposure of the workers needs to be continually monitored.

Authors+Show Affiliations

a Colegio Ciencias de la Salud, Escuela de Medicina, Escuela de Salud Pública , Colegio de Artes Liberales y Galapagos Institute for Arts and Sciences GAIAS; Universidad San Francisco de Quito , Quito , Ecuador.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24274152

Citation

Ortega, Fernando, et al. "Tracking Blood Lead and Zinc Protoporphyrin Levels in Andean Adults Working in a Lead Contaminated Environment." Journal of Toxicology and Environmental Health. Part A, vol. 76, no. 19, 2013, pp. 1111-20.
Ortega F, Counter SA, Buchanan LH, et al. Tracking blood lead and zinc protoporphyrin levels in Andean adults working in a lead contaminated environment. J Toxicol Environ Health A. 2013;76(19):1111-20.
Ortega, F., Counter, S. A., Buchanan, L. H., Parra, A. M., Collaguaso, M. A., & Jacobs, A. B. (2013). Tracking blood lead and zinc protoporphyrin levels in Andean adults working in a lead contaminated environment. Journal of Toxicology and Environmental Health. Part A, 76(19), 1111-20. https://doi.org/10.1080/15287394.2013.840708
Ortega F, et al. Tracking Blood Lead and Zinc Protoporphyrin Levels in Andean Adults Working in a Lead Contaminated Environment. J Toxicol Environ Health A. 2013;76(19):1111-20. PubMed PMID: 24274152.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tracking blood lead and zinc protoporphyrin levels in Andean adults working in a lead contaminated environment. AU - Ortega,Fernando, AU - Counter,S Allen, AU - Buchanan,Leo H, AU - Parra,Angelica Maria Coronel, AU - Collaguaso,Maria Angela, AU - Jacobs,Anthony B, PY - 2013/11/27/entrez PY - 2013/11/28/pubmed PY - 2014/1/18/medline SP - 1111 EP - 20 JF - Journal of toxicology and environmental health. Part A JO - J Toxicol Environ Health A VL - 76 IS - 19 N2 - The purpose of this study was to investigate current blood lead (PbB) and zinc protoporphyrin (ZPP) levels in adults presently living in environmentally Pb-contaminated Andean communities, and to compare the findings with the PbB and ZPP levels of Pb-exposed adult cohorts from the same study area tested between 1996 and 2007. Blood samples from 39 adults were measured for PbB and ZPP concentrations. The current mean PbB level (22.7 μg/dl) was significantly lower than the mean (37.9 μg/dl) of the initial 1996 cohort. PbB levels for the 1997, 1998, 2003, and 2006 cohorts were also significantly lower than the levels for the 1996 group. Elevated ZPP/heme ratios of 103.3, 128.4, and 134.2 μmol/mol were not significantly different for the 2006, 2007, and 2012 groups, indicating chronic Pb exposure. While ZPP levels of Andean Ecuadorian Pb-glazing workers have remained elevated, PbB levels declined. Lead exposure of the workers needs to be continually monitored. SN - 1528-7394 UR - https://www.unboundmedicine.com/medline/citation/24274152/Tracking_blood_lead_and_zinc_protoporphyrin_levels_in_Andean_adults_working_in_a_lead_contaminated_environment_ L2 - https://www.tandfonline.com/doi/full/10.1080/15287394.2013.840708 DB - PRIME DP - Unbound Medicine ER -