Tags

Type your tag names separated by a space and hit enter

Jumonji C domain protein JMJ705-mediated removal of histone H3 lysine 27 trimethylation is involved in defense-related gene activation in rice.
Plant Cell. 2013 Nov; 25(11):4725-36.PC

Abstract

Histone methylation is an important epigenetic modification in chromatin function, genome activity, and gene regulation. Dimethylated or trimethylated histone H3 lysine 27 (H3K27me2/3) marks silent or repressed genes involved in developmental processes and stress responses in plants. However, the role and the mechanism of the dynamic removal of H3K27me2/3 during gene activation remain unclear. Here, we show that the rice (Oryza sativa) Jumonji C (jmjC) protein gene JMJ705 encodes a histone lysine demethylase that specifically reverses H3K27me2/3. The expression of JMJ705 is induced by stress signals and during pathogen infection. Overexpression of the gene reduces the resting level of H3K27me2/3 resulting in preferential activation of H3K27me3-marked biotic stress-responsive genes and enhances rice resistance to the bacterial blight disease pathogen Xanthomonas oryzae pathovar oryzae. Mutation of the gene reduces plant resistance to the pathogen. Further analysis revealed that JMJ705 is involved in methyl jasmonate-induced dynamic removal of H3K27me3 and gene activation. The results suggest that JMJ705 is a biotic stress-responsive H3K27me2/3 demethylase that may remove H3K27me3 from marked defense-related genes and increase their basal and induced expression during pathogen infection.

Authors+Show Affiliations

National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 430070 Wuhan, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24280387

Citation

Li, Tiantian, et al. "Jumonji C Domain Protein JMJ705-mediated Removal of Histone H3 Lysine 27 Trimethylation Is Involved in Defense-related Gene Activation in Rice." The Plant Cell, vol. 25, no. 11, 2013, pp. 4725-36.
Li T, Chen X, Zhong X, et al. Jumonji C domain protein JMJ705-mediated removal of histone H3 lysine 27 trimethylation is involved in defense-related gene activation in rice. Plant Cell. 2013;25(11):4725-36.
Li, T., Chen, X., Zhong, X., Zhao, Y., Liu, X., Zhou, S., Cheng, S., & Zhou, D. X. (2013). Jumonji C domain protein JMJ705-mediated removal of histone H3 lysine 27 trimethylation is involved in defense-related gene activation in rice. The Plant Cell, 25(11), 4725-36. https://doi.org/10.1105/tpc.113.118802
Li T, et al. Jumonji C Domain Protein JMJ705-mediated Removal of Histone H3 Lysine 27 Trimethylation Is Involved in Defense-related Gene Activation in Rice. Plant Cell. 2013;25(11):4725-36. PubMed PMID: 24280387.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Jumonji C domain protein JMJ705-mediated removal of histone H3 lysine 27 trimethylation is involved in defense-related gene activation in rice. AU - Li,Tiantian, AU - Chen,Xiangsong, AU - Zhong,Xiaochao, AU - Zhao,Yu, AU - Liu,Xiaoyun, AU - Zhou,Shaoli, AU - Cheng,Saifeng, AU - Zhou,Dao-Xiu, Y1 - 2013/11/26/ PY - 2013/11/28/entrez PY - 2013/11/28/pubmed PY - 2014/10/24/medline SP - 4725 EP - 36 JF - The Plant cell JO - Plant Cell VL - 25 IS - 11 N2 - Histone methylation is an important epigenetic modification in chromatin function, genome activity, and gene regulation. Dimethylated or trimethylated histone H3 lysine 27 (H3K27me2/3) marks silent or repressed genes involved in developmental processes and stress responses in plants. However, the role and the mechanism of the dynamic removal of H3K27me2/3 during gene activation remain unclear. Here, we show that the rice (Oryza sativa) Jumonji C (jmjC) protein gene JMJ705 encodes a histone lysine demethylase that specifically reverses H3K27me2/3. The expression of JMJ705 is induced by stress signals and during pathogen infection. Overexpression of the gene reduces the resting level of H3K27me2/3 resulting in preferential activation of H3K27me3-marked biotic stress-responsive genes and enhances rice resistance to the bacterial blight disease pathogen Xanthomonas oryzae pathovar oryzae. Mutation of the gene reduces plant resistance to the pathogen. Further analysis revealed that JMJ705 is involved in methyl jasmonate-induced dynamic removal of H3K27me3 and gene activation. The results suggest that JMJ705 is a biotic stress-responsive H3K27me2/3 demethylase that may remove H3K27me3 from marked defense-related genes and increase their basal and induced expression during pathogen infection. SN - 1532-298X UR - https://www.unboundmedicine.com/medline/citation/24280387/Jumonji_C_domain_protein_JMJ705_mediated_removal_of_histone_H3_lysine_27_trimethylation_is_involved_in_defense_related_gene_activation_in_rice_ L2 - http://www.plantcell.org/cgi/pmidlookup?view=long&pmid=24280387 DB - PRIME DP - Unbound Medicine ER -