Tags

Type your tag names separated by a space and hit enter

Quantification of coronary artery plaque using 64-slice dual-source CT: comparison of semi-automatic and automatic computer-aided analysis based on intravascular ultrasonography as the gold standard.
Int J Cardiovasc Imaging. 2013 Dec; 29 Suppl 2:93-100.IJ

Abstract

We evaluated the feasibility of automatic computer-aided analysis (CAA) compared with semi-automatic CAA for differentiating lipid-rich from fibrous plaques based on coronary CT angiography (CCTA) imaging. Seventy-four coronary plaques in 57 patients were evaluated by CCTA using 64-slice dual-source CT. Quantitative analysis of coronary artery plaques was performed by measuring the relative volumes (low, medium, and calcified) of plaque components using automatic CAA and by measuring mean CT density using semi-automatic CAA. We compared the two plaque measurement methods for lipid-rich and fibrous plaques using Pearson's correlation. Intravascular ultrasonography was used as the goal standard for assessment of plaques. Mean CT density of plaques tended to increase in the order of lipid [36 ± 19 Hounsfield unit (HU)], fibrous (106 ± 34 HU), and then calcified plaques (882 ± 296 HU). The mean relative volumes of 'low' components measured by automatic CAA were 13.8 ± 4.6, 7.9 ± 6.7, and 3.5 ± 3.0 % for lipid, fibrous, and calcified plaques, respectively (r = -0.348, P = 0.022). The mean relative volumes of 'medium' components on automatic CAA were 12.9 ± 4.1, 15.7 ± 9.6, and 5.6 ± 4.8 % for lipid, fibrous, and calcified plaques, respectively (r = -0.385, P = 0.011). The mean relative volumes of low and medium components within plaques significantly correlated with the types of plaques. Plaque analysis using automatic CAA has the potential to differentiate lipid from fibrous plaques based on measurement of the relative volume percentages of the low and medium components.

Authors+Show Affiliations

Department of Radiology, Research Institute of Clinical Medicine, Institute of Cardiovascular Research, Chonbuk National University Hospital and Medical School, 634-18 Keumam-Dong, Chonju, Jeonbuk, 561-712, South Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24293043

Citation

Kim, Young Jun, et al. "Quantification of Coronary Artery Plaque Using 64-slice Dual-source CT: Comparison of Semi-automatic and Automatic Computer-aided Analysis Based On Intravascular Ultrasonography as the Gold Standard." The International Journal of Cardiovascular Imaging, vol. 29 Suppl 2, 2013, pp. 93-100.
Kim YJ, Jin GY, Kim EY, et al. Quantification of coronary artery plaque using 64-slice dual-source CT: comparison of semi-automatic and automatic computer-aided analysis based on intravascular ultrasonography as the gold standard. Int J Cardiovasc Imaging. 2013;29 Suppl 2:93-100.
Kim, Y. J., Jin, G. Y., Kim, E. Y., Han, Y. M., Chae, J. K., Lee, S. R., & Kwon, K. S. (2013). Quantification of coronary artery plaque using 64-slice dual-source CT: comparison of semi-automatic and automatic computer-aided analysis based on intravascular ultrasonography as the gold standard. The International Journal of Cardiovascular Imaging, 29 Suppl 2, 93-100. https://doi.org/10.1007/s10554-013-0333-4
Kim YJ, et al. Quantification of Coronary Artery Plaque Using 64-slice Dual-source CT: Comparison of Semi-automatic and Automatic Computer-aided Analysis Based On Intravascular Ultrasonography as the Gold Standard. Int J Cardiovasc Imaging. 2013;29 Suppl 2:93-100. PubMed PMID: 24293043.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Quantification of coronary artery plaque using 64-slice dual-source CT: comparison of semi-automatic and automatic computer-aided analysis based on intravascular ultrasonography as the gold standard. AU - Kim,Young Jun, AU - Jin,Gong Yong, AU - Kim,Eun Young, AU - Han,Young Min, AU - Chae,Jei Keon, AU - Lee,Sang Rok, AU - Kwon,Keun Sang, Y1 - 2013/11/30/ PY - 2013/10/28/received PY - 2013/11/18/accepted PY - 2013/12/3/entrez PY - 2013/12/3/pubmed PY - 2014/8/19/medline SP - 93 EP - 100 JF - The international journal of cardiovascular imaging JO - Int J Cardiovasc Imaging VL - 29 Suppl 2 N2 - We evaluated the feasibility of automatic computer-aided analysis (CAA) compared with semi-automatic CAA for differentiating lipid-rich from fibrous plaques based on coronary CT angiography (CCTA) imaging. Seventy-four coronary plaques in 57 patients were evaluated by CCTA using 64-slice dual-source CT. Quantitative analysis of coronary artery plaques was performed by measuring the relative volumes (low, medium, and calcified) of plaque components using automatic CAA and by measuring mean CT density using semi-automatic CAA. We compared the two plaque measurement methods for lipid-rich and fibrous plaques using Pearson's correlation. Intravascular ultrasonography was used as the goal standard for assessment of plaques. Mean CT density of plaques tended to increase in the order of lipid [36 ± 19 Hounsfield unit (HU)], fibrous (106 ± 34 HU), and then calcified plaques (882 ± 296 HU). The mean relative volumes of 'low' components measured by automatic CAA were 13.8 ± 4.6, 7.9 ± 6.7, and 3.5 ± 3.0 % for lipid, fibrous, and calcified plaques, respectively (r = -0.348, P = 0.022). The mean relative volumes of 'medium' components on automatic CAA were 12.9 ± 4.1, 15.7 ± 9.6, and 5.6 ± 4.8 % for lipid, fibrous, and calcified plaques, respectively (r = -0.385, P = 0.011). The mean relative volumes of low and medium components within plaques significantly correlated with the types of plaques. Plaque analysis using automatic CAA has the potential to differentiate lipid from fibrous plaques based on measurement of the relative volume percentages of the low and medium components. SN - 1875-8312 UR - https://www.unboundmedicine.com/medline/citation/24293043/Quantification_of_coronary_artery_plaque_using_64_slice_dual_source_CT:_comparison_of_semi_automatic_and_automatic_computer_aided_analysis_based_on_intravascular_ultrasonography_as_the_gold_standard_ L2 - https://doi.org/10.1007/s10554-013-0333-4 DB - PRIME DP - Unbound Medicine ER -