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Cannabidiol as a potential treatment for psychosis.
Eur Neuropsychopharmacol. 2014 Jan; 24(1):51-64.EN

Abstract

Although cannabis use is associated with an increased risk of developing psychosis, the cannabis constituent cannabidiol (CBD) may have antipsychotic properties. This review concisely describes the role of the endocannabinoid system in the development of psychosis and provides an overview of currently available animal, human experimental, imaging, epidemiological and clinical studies that investigated the antipsychotic properties of CBD. In this targeted literature review we performed a search for English articles using Medline and EMBASE. Studies were selected if they described experiments with psychosis models, psychotic symptoms or psychotic disorders as outcome measure and involved the use of CBD as intervention. Evidence from several research domains suggests that CBD shows potential for antipsychotic treatment.

Authors+Show Affiliations

Tergooi Hospital, Department of Psychiatry, Blaricum, The Netherlands.Brain Center Rudolf Magnus, University Medical Centre Utrecht, Department of Psychiatry, The Netherlands.Department of Psychosis Studies, Institute of Psychiatry, King's College London, UK.Brain Center Rudolf Magnus, University Medical Centre Utrecht, Department of Psychiatry, The Netherlands.Tergooi Hospital, Department of Psychiatry, Blaricum, The Netherlands.Brain Center Rudolf Magnus, University Medical Centre Utrecht, Department of Psychiatry, The Netherlands. Electronic address: m.p.m.boks@umcutrecht.nl.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

24309088

Citation

Schubart, C D., et al. "Cannabidiol as a Potential Treatment for Psychosis." European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology, vol. 24, no. 1, 2014, pp. 51-64.
Schubart CD, Sommer IE, Fusar-Poli P, et al. Cannabidiol as a potential treatment for psychosis. Eur Neuropsychopharmacol. 2014;24(1):51-64.
Schubart, C. D., Sommer, I. E., Fusar-Poli, P., de Witte, L., Kahn, R. S., & Boks, M. P. (2014). Cannabidiol as a potential treatment for psychosis. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology, 24(1), 51-64. https://doi.org/10.1016/j.euroneuro.2013.11.002
Schubart CD, et al. Cannabidiol as a Potential Treatment for Psychosis. Eur Neuropsychopharmacol. 2014;24(1):51-64. PubMed PMID: 24309088.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cannabidiol as a potential treatment for psychosis. AU - Schubart,C D, AU - Sommer,I E C, AU - Fusar-Poli,P, AU - de Witte,L, AU - Kahn,R S, AU - Boks,M P M, Y1 - 2013/11/15/ PY - 2013/02/22/received PY - 2013/11/05/revised PY - 2013/11/09/accepted PY - 2013/12/7/entrez PY - 2013/12/7/pubmed PY - 2014/9/13/medline KW - Antipsychotics KW - Cannabidiol KW - Cannabis KW - Psychosis KW - Schizophrenia KW - Treatment SP - 51 EP - 64 JF - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology JO - Eur Neuropsychopharmacol VL - 24 IS - 1 N2 - Although cannabis use is associated with an increased risk of developing psychosis, the cannabis constituent cannabidiol (CBD) may have antipsychotic properties. This review concisely describes the role of the endocannabinoid system in the development of psychosis and provides an overview of currently available animal, human experimental, imaging, epidemiological and clinical studies that investigated the antipsychotic properties of CBD. In this targeted literature review we performed a search for English articles using Medline and EMBASE. Studies were selected if they described experiments with psychosis models, psychotic symptoms or psychotic disorders as outcome measure and involved the use of CBD as intervention. Evidence from several research domains suggests that CBD shows potential for antipsychotic treatment. SN - 1873-7862 UR - https://www.unboundmedicine.com/medline/citation/24309088/Cannabidiol_as_a_potential_treatment_for_psychosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0924-977X(13)00332-5 DB - PRIME DP - Unbound Medicine ER -