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Structural analysis of proanthocyanidins isolated from fruit stone of Chinese hawthorn with potent antityrosinase and antioxidant activity.
J Agric Food Chem. 2014 Jan 08; 62(1):123-9.JA

Abstract

Proanthocyanidins were isolated from fruit stone of Chinese hawthorn (Crataegus pinnatifida Bge. var. major N.E.Br.). Their structures were analyzed and elucidated by methods of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and high performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI-MS). The results demonstrated that these compounds are complicated mixtures of homo- and heteropolymers consisting of procyanidin/procyanidin gallate and prodelphinidin. They possessed structural heterogeneity in monomer units, polymer length, and interflavan linkage (A-type and B-type). Their antityrosinase and antioxidant activity were then investigated. The results revealed that they can inhibit tyrosinase activities, including the monophenolase activity and the diphenolase activity. In addition, proanthocyanidins possessed potent antioxidant activity. Our studies revealed that proanthocyanidins isolated from fruit stone of Chinese hawthorn may be applied in food, agriculture, pharmaceutical, and cosmetic industries.

Authors+Show Affiliations

State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University , Xiamen 361005, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24313351

Citation

Chai, Wei-Ming, et al. "Structural Analysis of Proanthocyanidins Isolated From Fruit Stone of Chinese Hawthorn With Potent Antityrosinase and Antioxidant Activity." Journal of Agricultural and Food Chemistry, vol. 62, no. 1, 2014, pp. 123-9.
Chai WM, Chen CM, Gao YS, et al. Structural analysis of proanthocyanidins isolated from fruit stone of Chinese hawthorn with potent antityrosinase and antioxidant activity. J Agric Food Chem. 2014;62(1):123-9.
Chai, W. M., Chen, C. M., Gao, Y. S., Feng, H. L., Ding, Y. M., Shi, Y., Zhou, H. T., & Chen, Q. X. (2014). Structural analysis of proanthocyanidins isolated from fruit stone of Chinese hawthorn with potent antityrosinase and antioxidant activity. Journal of Agricultural and Food Chemistry, 62(1), 123-9. https://doi.org/10.1021/jf405385j
Chai WM, et al. Structural Analysis of Proanthocyanidins Isolated From Fruit Stone of Chinese Hawthorn With Potent Antityrosinase and Antioxidant Activity. J Agric Food Chem. 2014 Jan 8;62(1):123-9. PubMed PMID: 24313351.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Structural analysis of proanthocyanidins isolated from fruit stone of Chinese hawthorn with potent antityrosinase and antioxidant activity. AU - Chai,Wei-Ming, AU - Chen,Chih-Min, AU - Gao,Yu-Sen, AU - Feng,Hui-Ling, AU - Ding,Yu-Mei, AU - Shi,Yan, AU - Zhou,Han-Tao, AU - Chen,Qing-Xi, Y1 - 2013/12/17/ PY - 2013/12/10/entrez PY - 2013/12/10/pubmed PY - 2015/9/12/medline KW - HPLC-ESI-MS KW - MALDI-TOF MS KW - antioxidant activity KW - antityrosinase activity KW - hawthorn proanthocyanidins KW - structural analysis SP - 123 EP - 9 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 62 IS - 1 N2 - Proanthocyanidins were isolated from fruit stone of Chinese hawthorn (Crataegus pinnatifida Bge. var. major N.E.Br.). Their structures were analyzed and elucidated by methods of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and high performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI-MS). The results demonstrated that these compounds are complicated mixtures of homo- and heteropolymers consisting of procyanidin/procyanidin gallate and prodelphinidin. They possessed structural heterogeneity in monomer units, polymer length, and interflavan linkage (A-type and B-type). Their antityrosinase and antioxidant activity were then investigated. The results revealed that they can inhibit tyrosinase activities, including the monophenolase activity and the diphenolase activity. In addition, proanthocyanidins possessed potent antioxidant activity. Our studies revealed that proanthocyanidins isolated from fruit stone of Chinese hawthorn may be applied in food, agriculture, pharmaceutical, and cosmetic industries. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/24313351/Structural_analysis_of_proanthocyanidins_isolated_from_fruit_stone_of_Chinese_hawthorn_with_potent_antityrosinase_and_antioxidant_activity_ L2 - https://doi.org/10.1021/jf405385j DB - PRIME DP - Unbound Medicine ER -