Tags

Type your tag names separated by a space and hit enter

Increased subsequent risk of acute coronary syndrome for patients with depressive disorder: a nationwide population-based retrospective cohort study.
Psychiatry Clin Neurosci. 2014 Apr; 68(4):263-9.PC

Abstract

AIM

The purpose of this study was to explore the possible association between subsequent acute coronary syndrome (ACS) risk and depressive disorder.

METHODS

We used data from the National Health Insurance system of Taiwan to address the research topic. The exposure cohort contained 10 871 patients with new diagnoses of depressive disorders. Each patient was randomly frequency-matched for sex and age with four participants from the general population who did not have any ACS history before the index date (control group). Cox's proportion hazard regression analyses were conducted to estimate the relation between depressive disorders and subsequent ACS risk.

RESULTS

Among patients with depressive disorders, the overall risk for developing subsequent ACS was significantly higher than that of the control group (adjusted hazard ratio: 1.88, 95% confidence interval: 1.63-2.17). Further analysis revealed that the higher risk was observed in patients who were male, were of older age, or whose diagnosis was combined with other comorbidities.

CONCLUSIONS

The findings from this population-based retrospective cohort study suggest that depressive disorder is associated with an increased subsequent ACS risk.

Authors+Show Affiliations

Division of Cardiology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24313756

Citation

Lin, Yen-Nien, et al. "Increased Subsequent Risk of Acute Coronary Syndrome for Patients With Depressive Disorder: a Nationwide Population-based Retrospective Cohort Study." Psychiatry and Clinical Neurosciences, vol. 68, no. 4, 2014, pp. 263-9.
Lin YN, Lin CL, Chang YJ, et al. Increased subsequent risk of acute coronary syndrome for patients with depressive disorder: a nationwide population-based retrospective cohort study. Psychiatry Clin Neurosci. 2014;68(4):263-9.
Lin, Y. N., Lin, C. L., Chang, Y. J., Peng, C. L., Sung, F. C., Chang, K. C., & Kao, C. H. (2014). Increased subsequent risk of acute coronary syndrome for patients with depressive disorder: a nationwide population-based retrospective cohort study. Psychiatry and Clinical Neurosciences, 68(4), 263-9. https://doi.org/10.1111/pcn.12125
Lin YN, et al. Increased Subsequent Risk of Acute Coronary Syndrome for Patients With Depressive Disorder: a Nationwide Population-based Retrospective Cohort Study. Psychiatry Clin Neurosci. 2014;68(4):263-9. PubMed PMID: 24313756.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Increased subsequent risk of acute coronary syndrome for patients with depressive disorder: a nationwide population-based retrospective cohort study. AU - Lin,Yen-Nien, AU - Lin,Cheng-Li, AU - Chang,Yen-Jung, AU - Peng,Chiao-Ling, AU - Sung,Fung-Chang, AU - Chang,Kuan-Cheng, AU - Kao,Chia-Hung, Y1 - 2013/12/08/ PY - 2013/03/25/received PY - 2013/09/18/revised PY - 2013/09/21/accepted PY - 2013/12/10/entrez PY - 2013/12/10/pubmed PY - 2014/12/15/medline KW - acute coronary syndrome KW - depressive disorder KW - population-based cohort study SP - 263 EP - 9 JF - Psychiatry and clinical neurosciences JO - Psychiatry Clin. Neurosci. VL - 68 IS - 4 N2 - AIM: The purpose of this study was to explore the possible association between subsequent acute coronary syndrome (ACS) risk and depressive disorder. METHODS: We used data from the National Health Insurance system of Taiwan to address the research topic. The exposure cohort contained 10 871 patients with new diagnoses of depressive disorders. Each patient was randomly frequency-matched for sex and age with four participants from the general population who did not have any ACS history before the index date (control group). Cox's proportion hazard regression analyses were conducted to estimate the relation between depressive disorders and subsequent ACS risk. RESULTS: Among patients with depressive disorders, the overall risk for developing subsequent ACS was significantly higher than that of the control group (adjusted hazard ratio: 1.88, 95% confidence interval: 1.63-2.17). Further analysis revealed that the higher risk was observed in patients who were male, were of older age, or whose diagnosis was combined with other comorbidities. CONCLUSIONS: The findings from this population-based retrospective cohort study suggest that depressive disorder is associated with an increased subsequent ACS risk. SN - 1440-1819 UR - https://www.unboundmedicine.com/medline/citation/24313756/Increased_subsequent_risk_of_acute_coronary_syndrome_for_patients_with_depressive_disorder:_a_nationwide_population_based_retrospective_cohort_study_ L2 - https://doi.org/10.1111/pcn.12125 DB - PRIME DP - Unbound Medicine ER -