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Dietary protein is beneficial to bone health under conditions of adequate calcium intake: an update on clinical research.

Abstract

PURPOSE OF REVIEW

To underscore recent clinical studies, which evaluate the association between dietary protein and bone health.

RECENT FINDINGS

Epidemiologic studies show greater protein intake to be beneficial to bone health in adults. In addition, randomized controlled trials show that protein's positive effect on bone health is augmented by increased calcium intake. The relation between dietary protein and fracture risk is unclear. Dietary protein may positively impact bone health by increasing muscle mass, increasing calcium absorption, suppressing parathyroid hormone, and augmenting insulin-like growth factor 1 production; but the effects of other factors that contribute to this association, such as dietary protein dose and timing response, require further research.

SUMMARY

The positive effects of protein intake on bone health may only be beneficial under conditions of adequate calcium intake. Dietary protein's relation with fracture risk requires further investigation.

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  • Authors+Show Affiliations

    ,

    aThe Institute for Aging Research, Hebrew SeniorLife, Boston Massachusetts bDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts cDepartment of Allied Health Sciences, The University of Connecticut, Storrs, Connecticut, USA.

    ,

    Source

    MeSH

    Bone and Bones
    Calcium, Dietary
    Dietary Proteins
    Fractures, Bone
    Humans
    Insulin-Like Growth Factor I
    Meta-Analysis as Topic
    Parathyroid Hormone
    Randomized Controlled Trials as Topic

    Pub Type(s)

    Journal Article
    Research Support, N.I.H., Extramural
    Review

    Language

    eng

    PubMed ID

    24316688

    Citation

    Mangano, Kelsey M., et al. "Dietary Protein Is Beneficial to Bone Health Under Conditions of Adequate Calcium Intake: an Update On Clinical Research." Current Opinion in Clinical Nutrition and Metabolic Care, vol. 17, no. 1, 2014, pp. 69-74.
    Mangano KM, Sahni S, Kerstetter JE. Dietary protein is beneficial to bone health under conditions of adequate calcium intake: an update on clinical research. Curr Opin Clin Nutr Metab Care. 2014;17(1):69-74.
    Mangano, K. M., Sahni, S., & Kerstetter, J. E. (2014). Dietary protein is beneficial to bone health under conditions of adequate calcium intake: an update on clinical research. Current Opinion in Clinical Nutrition and Metabolic Care, 17(1), pp. 69-74. doi:10.1097/MCO.0000000000000013.
    Mangano KM, Sahni S, Kerstetter JE. Dietary Protein Is Beneficial to Bone Health Under Conditions of Adequate Calcium Intake: an Update On Clinical Research. Curr Opin Clin Nutr Metab Care. 2014;17(1):69-74. PubMed PMID: 24316688.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Dietary protein is beneficial to bone health under conditions of adequate calcium intake: an update on clinical research. AU - Mangano,Kelsey M, AU - Sahni,Shivani, AU - Kerstetter,Jane E, PY - 2013/12/10/entrez PY - 2013/12/10/pubmed PY - 2014/8/2/medline SP - 69 EP - 74 JF - Current opinion in clinical nutrition and metabolic care JO - Curr Opin Clin Nutr Metab Care VL - 17 IS - 1 N2 - PURPOSE OF REVIEW: To underscore recent clinical studies, which evaluate the association between dietary protein and bone health. RECENT FINDINGS: Epidemiologic studies show greater protein intake to be beneficial to bone health in adults. In addition, randomized controlled trials show that protein's positive effect on bone health is augmented by increased calcium intake. The relation between dietary protein and fracture risk is unclear. Dietary protein may positively impact bone health by increasing muscle mass, increasing calcium absorption, suppressing parathyroid hormone, and augmenting insulin-like growth factor 1 production; but the effects of other factors that contribute to this association, such as dietary protein dose and timing response, require further research. SUMMARY: The positive effects of protein intake on bone health may only be beneficial under conditions of adequate calcium intake. Dietary protein's relation with fracture risk requires further investigation. SN - 1473-6519 UR - https://www.unboundmedicine.com/medline/citation/24316688/full_citation L2 - http://Insights.ovid.com/pubmed?pmid=24316688 DB - PRIME DP - Unbound Medicine ER -