Tags

Type your tag names separated by a space and hit enter

Immune modulation property of Lactobacillus paracasei NCC2461 (ST11) strain and impact on skin defences.
Benef Microbes. 2014 Jun 01; 5(2):129-36.BM

Abstract

The gut intestinal tract harbours a complex microbiota. Disturbances in the microbiota composition have been associated with several immune dysfunctions such as inflammatory diseases. Specific strains of probiotics have shown to beneficially influence the composition and/or metabolic activity of the endogenous microbiota. Taking advantage of the plasticity of the immune system, the probiotic strain NCC2461 (i.e. ST11 or CNCM I-2116) supports and/or restores homeostasis in reaction to different physiopathological conditions. The potential of NCC2461 to modulate both mucosal and systemic immune functions led us to test its impact on skin physiology. Even though clear mechanisms explaining gut-skin interaction are still lacking, a set of experimental and clinical data reviewed herein have shown that NCC2461 exerts its effects beyond the gut and confers benefits at the skin level. It contributes to the reinforcement of skin barrier function, decreases skin sensitivity and modulates the skin immune system leading to the preservation of skin homeostasis.

Authors+Show Affiliations

Nestle Research Center, Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland.Nestle Research Center, Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland.Nestle Research Center, Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland.Nestle Research Center, Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland.Nestle Research Center, Vers-chez-les-Blanc, P.O. Box 44, 1000 Lausanne 26, Switzerland.L'Oreal Research and Innovation, River Plaza, 25-29 Quai Aulagnier, 92665 Asnières-sur-Seine, France.LéOreal, Physiology and pharmacology, 89 Rue General Roguet, 92583 Clichy, France.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24322880

Citation

Benyacoub, J, et al. "Immune Modulation Property of Lactobacillus Paracasei NCC2461 (ST11) Strain and Impact On Skin Defences." Beneficial Microbes, vol. 5, no. 2, 2014, pp. 129-36.
Benyacoub J, Bosco N, Blanchard C, et al. Immune modulation property of Lactobacillus paracasei NCC2461 (ST11) strain and impact on skin defences. Benef Microbes. 2014;5(2):129-36.
Benyacoub, J., Bosco, N., Blanchard, C., Demont, A., Philippe, D., Castiel-Higounenc, I., & Guéniche, A. (2014). Immune modulation property of Lactobacillus paracasei NCC2461 (ST11) strain and impact on skin defences. Beneficial Microbes, 5(2), 129-36. https://doi.org/10.3920/BM2013.0014
Benyacoub J, et al. Immune Modulation Property of Lactobacillus Paracasei NCC2461 (ST11) Strain and Impact On Skin Defences. Benef Microbes. 2014 Jun 1;5(2):129-36. PubMed PMID: 24322880.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Immune modulation property of Lactobacillus paracasei NCC2461 (ST11) strain and impact on skin defences. AU - Benyacoub,J, AU - Bosco,N, AU - Blanchard,C, AU - Demont,A, AU - Philippe,D, AU - Castiel-Higounenc,I, AU - Guéniche,A, PY - 2013/12/11/entrez PY - 2013/12/11/pubmed PY - 2014/11/18/medline KW - ST11 KW - gut-skin axis KW - microbiota KW - probiotic SP - 129 EP - 36 JF - Beneficial microbes JO - Benef Microbes VL - 5 IS - 2 N2 - The gut intestinal tract harbours a complex microbiota. Disturbances in the microbiota composition have been associated with several immune dysfunctions such as inflammatory diseases. Specific strains of probiotics have shown to beneficially influence the composition and/or metabolic activity of the endogenous microbiota. Taking advantage of the plasticity of the immune system, the probiotic strain NCC2461 (i.e. ST11 or CNCM I-2116) supports and/or restores homeostasis in reaction to different physiopathological conditions. The potential of NCC2461 to modulate both mucosal and systemic immune functions led us to test its impact on skin physiology. Even though clear mechanisms explaining gut-skin interaction are still lacking, a set of experimental and clinical data reviewed herein have shown that NCC2461 exerts its effects beyond the gut and confers benefits at the skin level. It contributes to the reinforcement of skin barrier function, decreases skin sensitivity and modulates the skin immune system leading to the preservation of skin homeostasis. SN - 1876-2891 UR - https://www.unboundmedicine.com/medline/citation/24322880/Immune_modulation_property_of_Lactobacillus_paracasei_NCC2461__ST11__strain_and_impact_on_skin_defences_ L2 - https://www.wageningenacademic.com/doi/10.3920/BM2013.0014?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -