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Evaluation of trace elements, oxidant/antioxidant status, vitamin C and β-carotene in dogs with dermatophytosis.
Mycoses. 2014 Jun; 57(6):358-65.M

Abstract

The aim of the study was to determine zinc, copper and iron levels, erythrocyte oxidant/antioxidant status, vitamin C and β-carotene in dogs with dermatophytosis. A total of 23 dogs with clinically established diagnosis of dermatophytosis by trichogram and positive fungal culture and six dogs as control were included in this study. On cultural examination 52.17% fungal isolates were found to be Microsporum canis, 30.43% were Trichophyton mentagrophytes and 17.39% were M. gypseum. In comparison to healthy control, the dogs with dermatophytosis had significantly lower levels of zinc (P < 0.01), copper (P < 0.05), β-carotene and vitamin C levels (P < 0.05) and activities of superoxide dismutase (SOD) (P < 0.05) and catalase (P < 0.01), whereas the iron (P < 0.05) and malondialdehyde (MDA) (P < 0.01) levels were significantly increased. On correlation analysis, SOD activity was observed to be positively correlated (P < 0.05) with zinc and copper in both healthy and dermatophytosis affected dogs. In dermatophytosis affected dogs the MDA levels were negatively correlated (P < 0.05) with iron, β-carotene levels and the activities of antioxidant enzymes; SOD and catalase. Our results demonstrated that dermatophytosis in dogs is associated with significant alteration in oxidant/antioxidant balance and trace elements. It might be secondary consequence of dermatophytosis infection or contributing factor in its pathogenesis.

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Authors+Show Affiliations

Beigh SA
Division of Veterinary Medicine, Faculty of Veterinary Science and Animal Husbandry, Shere-e-Kashmir University of Agricultural Sciences and Technology of Jammu, R.S. Pura, Jammu (J & K), India.
Soodan JS
No affiliation info available
Singh R
No affiliation info available
Khan AM
No affiliation info available
Dar MA
No affiliation info available

MeSH

AnimalsAntioxidantsArthrodermataceaeDog DiseasesDogsErythrocytesFemaleMaleMicrosporumOxidantsTineaTrace ElementsTrichophytonVitamins

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24329950

Citation

Beigh, S A., et al. "Evaluation of Trace Elements, Oxidant/antioxidant Status, Vitamin C and Β-carotene in Dogs With Dermatophytosis." Mycoses, vol. 57, no. 6, 2014, pp. 358-65.
Beigh SA, Soodan JS, Singh R, et al. Evaluation of trace elements, oxidant/antioxidant status, vitamin C and β-carotene in dogs with dermatophytosis. Mycoses. 2014;57(6):358-65.
Beigh, S. A., Soodan, J. S., Singh, R., Khan, A. M., & Dar, M. A. (2014). Evaluation of trace elements, oxidant/antioxidant status, vitamin C and β-carotene in dogs with dermatophytosis. Mycoses, 57(6), 358-65. https://doi.org/10.1111/myc.12163
Beigh SA, et al. Evaluation of Trace Elements, Oxidant/antioxidant Status, Vitamin C and Β-carotene in Dogs With Dermatophytosis. Mycoses. 2014;57(6):358-65. PubMed PMID: 24329950.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of trace elements, oxidant/antioxidant status, vitamin C and β-carotene in dogs with dermatophytosis. AU - Beigh,S A, AU - Soodan,J S, AU - Singh,R, AU - Khan,A M, AU - Dar,M A, Y1 - 2013/12/13/ PY - 2013/06/26/received PY - 2013/11/17/revised PY - 2013/11/19/accepted PY - 2013/12/17/entrez PY - 2013/12/18/pubmed PY - 2014/12/20/medline KW - Antioxidants KW - copper KW - dermatophytosis KW - iron KW - oxidants KW - vitamin C and zinc KW - β-carotene SP - 358 EP - 65 JF - Mycoses JO - Mycoses VL - 57 IS - 6 N2 - The aim of the study was to determine zinc, copper and iron levels, erythrocyte oxidant/antioxidant status, vitamin C and β-carotene in dogs with dermatophytosis. A total of 23 dogs with clinically established diagnosis of dermatophytosis by trichogram and positive fungal culture and six dogs as control were included in this study. On cultural examination 52.17% fungal isolates were found to be Microsporum canis, 30.43% were Trichophyton mentagrophytes and 17.39% were M. gypseum. In comparison to healthy control, the dogs with dermatophytosis had significantly lower levels of zinc (P < 0.01), copper (P < 0.05), β-carotene and vitamin C levels (P < 0.05) and activities of superoxide dismutase (SOD) (P < 0.05) and catalase (P < 0.01), whereas the iron (P < 0.05) and malondialdehyde (MDA) (P < 0.01) levels were significantly increased. On correlation analysis, SOD activity was observed to be positively correlated (P < 0.05) with zinc and copper in both healthy and dermatophytosis affected dogs. In dermatophytosis affected dogs the MDA levels were negatively correlated (P < 0.05) with iron, β-carotene levels and the activities of antioxidant enzymes; SOD and catalase. Our results demonstrated that dermatophytosis in dogs is associated with significant alteration in oxidant/antioxidant balance and trace elements. It might be secondary consequence of dermatophytosis infection or contributing factor in its pathogenesis. SN - 1439-0507 UR - https://www.unboundmedicine.com/medline/citation/24329950/Evaluation_of_trace_elements_oxidant/antioxidant_status_vitamin_C_and_β_carotene_in_dogs_with_dermatophytosis_ DB - PRIME DP - Unbound Medicine ER -