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Electrophysiological measurements of the stria vascularis potentials in vivo.
Hear Res. 1987; 25(1):35-43.HR

Abstract

Glass microelectrodes were introduced into the stria vascularis (SV) to measure the DC potential profile of the SV in vivo from its apical as well as basal side. The K+ concentration gradient in the lateral cochlear wall was measured by means of double barrel K+-selective microelectrodes. A positive potential 10.4 +/- 6.3 mV higher than the endocochlear potential (EP) was found in the SV. In noise-exposed animals the positive potential found in the SV was 14.6 +/- 7.2 mV higher than the EP. K+ concentration observed during penetration into the SV was in the range of 50-100 mmol/l. Simultaneous measurement of the DC positive potential in the SV and EP showed a nearly parallel time course during anoxia with a tendency to increase the difference between the SV potential and the EP. The difference reached approximately 30 mV 20 min after the beginning of anoxia. It may be assumed that the electrogenic pump localized at the basolateral membrane of the marginal cell (MC) is a source of the positive potential inside the MC and is hence a source of the potential drop across the luminal side of the MC membrane.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2433260

Citation

Melichar, I, and J Syka. "Electrophysiological Measurements of the Stria Vascularis Potentials in Vivo." Hearing Research, vol. 25, no. 1, 1987, pp. 35-43.
Melichar I, Syka J. Electrophysiological measurements of the stria vascularis potentials in vivo. Hear Res. 1987;25(1):35-43.
Melichar, I., & Syka, J. (1987). Electrophysiological measurements of the stria vascularis potentials in vivo. Hearing Research, 25(1), 35-43.
Melichar I, Syka J. Electrophysiological Measurements of the Stria Vascularis Potentials in Vivo. Hear Res. 1987;25(1):35-43. PubMed PMID: 2433260.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Electrophysiological measurements of the stria vascularis potentials in vivo. AU - Melichar,I, AU - Syka,J, PY - 1987/1/1/pubmed PY - 1987/1/1/medline PY - 1987/1/1/entrez SP - 35 EP - 43 JF - Hearing research JO - Hear. Res. VL - 25 IS - 1 N2 - Glass microelectrodes were introduced into the stria vascularis (SV) to measure the DC potential profile of the SV in vivo from its apical as well as basal side. The K+ concentration gradient in the lateral cochlear wall was measured by means of double barrel K+-selective microelectrodes. A positive potential 10.4 +/- 6.3 mV higher than the endocochlear potential (EP) was found in the SV. In noise-exposed animals the positive potential found in the SV was 14.6 +/- 7.2 mV higher than the EP. K+ concentration observed during penetration into the SV was in the range of 50-100 mmol/l. Simultaneous measurement of the DC positive potential in the SV and EP showed a nearly parallel time course during anoxia with a tendency to increase the difference between the SV potential and the EP. The difference reached approximately 30 mV 20 min after the beginning of anoxia. It may be assumed that the electrogenic pump localized at the basolateral membrane of the marginal cell (MC) is a source of the positive potential inside the MC and is hence a source of the potential drop across the luminal side of the MC membrane. SN - 0378-5955 UR - https://www.unboundmedicine.com/medline/citation/2433260/Electrophysiological_measurements_of_the_stria_vascularis_potentials_in_vivo_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0378-5955(87)90077-3 DB - PRIME DP - Unbound Medicine ER -