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When and how to perform genetic testing for inherited colorectal cancer syndromes.
J Natl Compr Canc Netw 2013; 11(12):1577-83JN

Abstract

The 2013 NCCN Clinical Practice Guidelines in Oncology for Colorectal Cancer Screening address the evaluation and management of patients at risk of inherited susceptibility to colorectal cancer. These patients include the 2 broad categories of patients with familial adenomatous polyposis and its variants, and those with hereditary nonpolyposis colorectal cancer, or Lynch syndrome. This article provides a somewhat personal, yet hopefully evidence-based, approach to the questions of when to test individuals for inherited susceptibility, and how to do so. "When" can be taken to mean "under what circumstance" and "at what age"; this article attempts to speak to each sense of the term.

Authors+Show Affiliations

From the Department of Gastroenterology, Hepatology & Nutrition, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24335689

Citation

Lynch, Patrick M.. "When and How to Perform Genetic Testing for Inherited Colorectal Cancer Syndromes." Journal of the National Comprehensive Cancer Network : JNCCN, vol. 11, no. 12, 2013, pp. 1577-83.
Lynch PM. When and how to perform genetic testing for inherited colorectal cancer syndromes. J Natl Compr Canc Netw. 2013;11(12):1577-83.
Lynch, P. M. (2013). When and how to perform genetic testing for inherited colorectal cancer syndromes. Journal of the National Comprehensive Cancer Network : JNCCN, 11(12), pp. 1577-83.
Lynch PM. When and How to Perform Genetic Testing for Inherited Colorectal Cancer Syndromes. J Natl Compr Canc Netw. 2013 Dec 1;11(12):1577-83. PubMed PMID: 24335689.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - When and how to perform genetic testing for inherited colorectal cancer syndromes. A1 - Lynch,Patrick M, PY - 2013/12/17/entrez PY - 2013/12/18/pubmed PY - 2014/8/15/medline SP - 1577 EP - 83 JF - Journal of the National Comprehensive Cancer Network : JNCCN JO - J Natl Compr Canc Netw VL - 11 IS - 12 N2 - The 2013 NCCN Clinical Practice Guidelines in Oncology for Colorectal Cancer Screening address the evaluation and management of patients at risk of inherited susceptibility to colorectal cancer. These patients include the 2 broad categories of patients with familial adenomatous polyposis and its variants, and those with hereditary nonpolyposis colorectal cancer, or Lynch syndrome. This article provides a somewhat personal, yet hopefully evidence-based, approach to the questions of when to test individuals for inherited susceptibility, and how to do so. "When" can be taken to mean "under what circumstance" and "at what age"; this article attempts to speak to each sense of the term. SN - 1540-1413 UR - https://www.unboundmedicine.com/medline/citation/24335689/When_and_how_to_perform_genetic_testing_for_inherited_colorectal_cancer_syndromes_ L2 - http://www.diseaseinfosearch.org/result/1746 DB - PRIME DP - Unbound Medicine ER -