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Mean platelet volume levels in children with adenoid hypertrophy.
J Craniofac Surg 2014; 25(1):e29-31JC

Abstract

Adenoid hypertrophy (AH) is a common disorder in children, resulting in chronic nasal congestion. This chronic congestion should be evaluated carefully because it can lead to chronic upper airway obstruction. Many authors have suggested that increased nasal resistance to respiration may cause disturbances in the pulmonary ventilation and carry the risk of cardiopulmonary diseases. Mean platelet volume (MPV) is a marker of platelet function and is positively associated with indicators of platelet activity. Mean platelet volume is an indicator of larger and more reactive platelets and has been shown to be increased in patients with vascular disease, including peripheral, pulmonary, and coronary artery disease. Recently, MPV levels have also been shown to be increased in patients with severe obstructive sleep apnea, and marked nasal septal deviation. Moreover, increased MPV has also been shown to have a prognostic role in cardiovascular disease. We investigated whether MPV is higher in patients with AH and whether higher MPV levels can be reduced by adenoidectomy. To the best of our knowledge, this is the first study to investigate MPV in patients with AH. Our results suggest that MPV, a determinant of platelet activation, is elevated in patients with AH and adenoidectomy is an effective therapeutic measure in such patients. Increased platelet activation may be related to an increase of cardiopulmonary risk in patients with AH.

Authors+Show Affiliations

From the Departments of *Otolaryngology, and †Pediatric Surgery, Evliya Celebi Training and Research Hospital, Dumlupınar University, Kutahya, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24336044

Citation

Kucur, Cuneyt, et al. "Mean Platelet Volume Levels in Children With Adenoid Hypertrophy." The Journal of Craniofacial Surgery, vol. 25, no. 1, 2014, pp. e29-31.
Kucur C, Kulekci S, Zorlu A, et al. Mean platelet volume levels in children with adenoid hypertrophy. J Craniofac Surg. 2014;25(1):e29-31.
Kucur, C., Kulekci, S., Zorlu, A., Savran, B., Oghan, F., & Yildirim, N. (2014). Mean platelet volume levels in children with adenoid hypertrophy. The Journal of Craniofacial Surgery, 25(1), pp. e29-31. doi:10.1097/SCS.0b013e3182a2eddd.
Kucur C, et al. Mean Platelet Volume Levels in Children With Adenoid Hypertrophy. J Craniofac Surg. 2014;25(1):e29-31. PubMed PMID: 24336044.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mean platelet volume levels in children with adenoid hypertrophy. AU - Kucur,Cuneyt, AU - Kulekci,Semra, AU - Zorlu,Aylin, AU - Savran,Bircan, AU - Oghan,Fatih, AU - Yildirim,Nadir, PY - 2013/12/17/entrez PY - 2013/12/18/pubmed PY - 2015/6/13/medline SP - e29 EP - 31 JF - The Journal of craniofacial surgery JO - J Craniofac Surg VL - 25 IS - 1 N2 - Adenoid hypertrophy (AH) is a common disorder in children, resulting in chronic nasal congestion. This chronic congestion should be evaluated carefully because it can lead to chronic upper airway obstruction. Many authors have suggested that increased nasal resistance to respiration may cause disturbances in the pulmonary ventilation and carry the risk of cardiopulmonary diseases. Mean platelet volume (MPV) is a marker of platelet function and is positively associated with indicators of platelet activity. Mean platelet volume is an indicator of larger and more reactive platelets and has been shown to be increased in patients with vascular disease, including peripheral, pulmonary, and coronary artery disease. Recently, MPV levels have also been shown to be increased in patients with severe obstructive sleep apnea, and marked nasal septal deviation. Moreover, increased MPV has also been shown to have a prognostic role in cardiovascular disease. We investigated whether MPV is higher in patients with AH and whether higher MPV levels can be reduced by adenoidectomy. To the best of our knowledge, this is the first study to investigate MPV in patients with AH. Our results suggest that MPV, a determinant of platelet activation, is elevated in patients with AH and adenoidectomy is an effective therapeutic measure in such patients. Increased platelet activation may be related to an increase of cardiopulmonary risk in patients with AH. SN - 1536-3732 UR - https://www.unboundmedicine.com/medline/citation/24336044/Mean_platelet_volume_levels_in_children_with_adenoid_hypertrophy_ L2 - http://Insights.ovid.com/pubmed?pmid=24336044 DB - PRIME DP - Unbound Medicine ER -