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[Significance of serum iron in the differential diagnosis between vasovagal syncope and postural orthostatic tachycardia syndrome in children].
Beijing Da Xue Xue Bao Yi Xue Ban. 2013 Dec 18; 45(6):923-7.BD

Abstract

OBJECTIVE

To explore the predictive value of serum iron in differentiating between vasovagal syncope (VVS) and postural orthostatic tachycardia syndrome (POTS) in children.

METHODS

Totally 57 children (aged 4-17 years, POTS 40 cases, and VVS 17 cases) who were at the syncope clinic or admitted to the Department of Pediatrics, Peking University First Hospital from August 2009 to September 2012 were included in the study. The diagnoses were analyzed by the value of serum iron and receiver operating characteristic (ROC) curves used to explore the predictive value of different serum iron in differential diagnosis between VVS and POTS.

RESULTS

There were significant differences in the median value of POTS [17.4 (interquartile range 13.5 -21.8) μmol/L] and VVS [8.9 (interquartile range 7.5-17.6) μmol/L] (P<0.01). When the value of serum iron was 11.8 μmol/L, the sensitivity and specificity of the differential diagnosis between VVS and POTS were 92.5% and 64.7%, respectively.

CONCLUSION

The serum iron might be used as an initial diagnostic method in differential diagnosis between VVS and POTS, based on the history of the patients.

Authors+Show Affiliations

Li JW
Department of Pediatrics, Peking University First Hospital, Beijing 100034, China.
Zhang QY
No affiliation info available
Gao J
No affiliation info available
Jin HF
No affiliation info available
Du JB
No affiliation info available

MeSH

AdolescentChildDiagnosis, DifferentialFemaleHumansIronMalePostural Orthostatic Tachycardia SyndromeROC CurveSensitivity and SpecificitySyncope, Vasovagal

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

24343075

Citation

Li, Jia-wei, et al. "[Significance of Serum Iron in the Differential Diagnosis Between Vasovagal Syncope and Postural Orthostatic Tachycardia Syndrome in Children]." Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences, vol. 45, no. 6, 2013, pp. 923-7.
Li JW, Zhang QY, Gao J, et al. [Significance of serum iron in the differential diagnosis between vasovagal syncope and postural orthostatic tachycardia syndrome in children]. Beijing Da Xue Xue Bao Yi Xue Ban. 2013;45(6):923-7.
Li, J. W., Zhang, Q. Y., Gao, J., Jin, H. F., & Du, J. B. (2013). [Significance of serum iron in the differential diagnosis between vasovagal syncope and postural orthostatic tachycardia syndrome in children]. Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences, 45(6), 923-7.
Li JW, et al. [Significance of Serum Iron in the Differential Diagnosis Between Vasovagal Syncope and Postural Orthostatic Tachycardia Syndrome in Children]. Beijing Da Xue Xue Bao Yi Xue Ban. 2013 Dec 18;45(6):923-7. PubMed PMID: 24343075.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Significance of serum iron in the differential diagnosis between vasovagal syncope and postural orthostatic tachycardia syndrome in children]. AU - Li,Jia-wei, AU - Zhang,Qing-you, AU - Gao,Jie, AU - Jin,Hong-fang, AU - Du,Jun-bao, PY - 2013/12/18/entrez PY - 2013/12/18/pubmed PY - 2014/8/3/medline SP - 923 EP - 7 JF - Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences JO - Beijing Da Xue Xue Bao Yi Xue Ban VL - 45 IS - 6 N2 - OBJECTIVE: To explore the predictive value of serum iron in differentiating between vasovagal syncope (VVS) and postural orthostatic tachycardia syndrome (POTS) in children. METHODS: Totally 57 children (aged 4-17 years, POTS 40 cases, and VVS 17 cases) who were at the syncope clinic or admitted to the Department of Pediatrics, Peking University First Hospital from August 2009 to September 2012 were included in the study. The diagnoses were analyzed by the value of serum iron and receiver operating characteristic (ROC) curves used to explore the predictive value of different serum iron in differential diagnosis between VVS and POTS. RESULTS: There were significant differences in the median value of POTS [17.4 (interquartile range 13.5 -21.8) μmol/L] and VVS [8.9 (interquartile range 7.5-17.6) μmol/L] (P<0.01). When the value of serum iron was 11.8 μmol/L, the sensitivity and specificity of the differential diagnosis between VVS and POTS were 92.5% and 64.7%, respectively. CONCLUSION: The serum iron might be used as an initial diagnostic method in differential diagnosis between VVS and POTS, based on the history of the patients. SN - 1671-167X UR - https://www.unboundmedicine.com/medline/citation/24343075/[Significance_of_serum_iron_in_the_differential_diagnosis_between_vasovagal_syncope_and_postural_orthostatic_tachycardia_syndrome_in_children]_ DB - PRIME DP - Unbound Medicine ER -