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Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011.
Arch Virol 2014; 159(6):1475-9AV

Abstract

As a zoonotic infectious disease, orf outbreaks have been reported in China in recent years. However, molecular epidemiology analysis has not been performed for Chinese orf virus (ORFV) strains. Here, we have identified 13 ORFVs from goats and sheep in China between 2009 and 2011. Thirty-four complete B2L sequences were used to construct a phylogenetic tree to elucidate the molecular epidemiology of ORFV in China. Nucleotide sequences of B2L genes of clinical samples and attenuated vaccine strains were aligned and compared. Three genotypes were found by molecular epidemiology analysis. Amino acid substitutions were dispersed among B2 polypeptides from wild and attenuated ORFV strains.

Authors+Show Affiliations

State Key Laboratory of Veterinary Etiological Biology, National Foot and Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping No. 1 Yanchangpu, Lanzhou, 730046, Gansu, People's Republic of China, zks009@126.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24343266

Citation

Zhang, Keshan, et al. "Comparison and Phylogenetic Analysis Based On the B2L Gene of Orf Virus From Goats and Sheep in China During 2009-2011." Archives of Virology, vol. 159, no. 6, 2014, pp. 1475-9.
Zhang K, Liu Y, Kong H, et al. Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011. Arch Virol. 2014;159(6):1475-9.
Zhang, K., Liu, Y., Kong, H., Shang, Y., & Liu, X. (2014). Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011. Archives of Virology, 159(6), pp. 1475-9. doi:10.1007/s00705-013-1946-6.
Zhang K, et al. Comparison and Phylogenetic Analysis Based On the B2L Gene of Orf Virus From Goats and Sheep in China During 2009-2011. Arch Virol. 2014;159(6):1475-9. PubMed PMID: 24343266.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011. AU - Zhang,Keshan, AU - Liu,Yongjie, AU - Kong,Hanjin, AU - Shang,Youjun, AU - Liu,Xiangtao, Y1 - 2013/12/17/ PY - 2013/09/19/received PY - 2013/11/01/accepted PY - 2013/12/18/entrez PY - 2013/12/18/pubmed PY - 2014/7/22/medline SP - 1475 EP - 9 JF - Archives of virology JO - Arch. Virol. VL - 159 IS - 6 N2 - As a zoonotic infectious disease, orf outbreaks have been reported in China in recent years. However, molecular epidemiology analysis has not been performed for Chinese orf virus (ORFV) strains. Here, we have identified 13 ORFVs from goats and sheep in China between 2009 and 2011. Thirty-four complete B2L sequences were used to construct a phylogenetic tree to elucidate the molecular epidemiology of ORFV in China. Nucleotide sequences of B2L genes of clinical samples and attenuated vaccine strains were aligned and compared. Three genotypes were found by molecular epidemiology analysis. Amino acid substitutions were dispersed among B2 polypeptides from wild and attenuated ORFV strains. SN - 1432-8798 UR - https://www.unboundmedicine.com/medline/citation/24343266/Comparison_and_phylogenetic_analysis_based_on_the_B2L_gene_of_orf_virus_from_goats_and_sheep_in_China_during_2009_2011_ L2 - https://dx.doi.org/10.1007/s00705-013-1946-6 DB - PRIME DP - Unbound Medicine ER -