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Phytochemical and pharmacological studies on Radix Angelica sinensis.
Chin J Nat Med. 2013 Nov; 11(6):577-87.CJ

Abstract

The roots of Angelica sinensis (RAS), are a Chinese herbal medicine traditionally used in prescriptions for replenishing blood, treating abnormal menstruation, and other women's diseases. It has also been widely marketed as health food for women's care in Asia, and as a dietary supplement in Europe and America. RAS is well-known for its hematopoietic, antioxidant, and immunoregulatory activities. RAS also possesses anti-cancer, memory, radioprotective, and neuroprotective effects. Phytochemical investigations on this plant led to organic acids, phthalides, polysaccharides, and other metabolites. Based on recent animal studies and clinical trials, RAS has been used in the treatment of gynecologic diseases, cardio-cerebrovascular disease, nervous system diseases, and nephrotic syndrome. In this review, the recent phytochemical and pharmacological studies, drug-drug interactions, clinical applications, and toxicity of RAS are summarized.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Chen XP
School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China; State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China; Tasly R&D Institute, Tianjin Tasly Group Co., Ltd., Tianjin 300410, China.
Li W
Tasly R&D Institute, Tianjin Tasly Group Co., Ltd., Tianjin 300410, China.
Xiao XF
Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Zhang LL
Tasly R&D Institute, Tianjin Tasly Group Co., Ltd., Tianjin 300410, China.
Liu CX
State Key Laboratory of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China. Electronic address: liuchangxiao@163.com.

MeSH

Angelica sinensisAnimalsDrugs, Chinese HerbalHumansPhytotherapyPlant Roots

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

24345498

Citation

Chen, Xiao-Peng, et al. "Phytochemical and Pharmacological Studies On Radix Angelica Sinensis." Chinese Journal of Natural Medicines, vol. 11, no. 6, 2013, pp. 577-87.
Chen XP, Li W, Xiao XF, et al. Phytochemical and pharmacological studies on Radix Angelica sinensis. Chin J Nat Med. 2013;11(6):577-87.
Chen, X. P., Li, W., Xiao, X. F., Zhang, L. L., & Liu, C. X. (2013). Phytochemical and pharmacological studies on Radix Angelica sinensis. Chinese Journal of Natural Medicines, 11(6), 577-87. https://doi.org/10.1016/S1875-5364(13)60067-9
Chen XP, et al. Phytochemical and Pharmacological Studies On Radix Angelica Sinensis. Chin J Nat Med. 2013;11(6):577-87. PubMed PMID: 24345498.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phytochemical and pharmacological studies on Radix Angelica sinensis. AU - Chen,Xiao-Peng, AU - Li,Wei, AU - Xiao,Xue-Feng, AU - Zhang,Lan-Lan, AU - Liu,Chang-Xiao, PY - 2013/02/20/received PY - 2013/12/19/entrez PY - 2013/12/19/pubmed PY - 2014/7/30/medline KW - Chemical constituents KW - Clinical applications KW - Interactions KW - Pharmacological effect KW - Radix Angelica Sinensis KW - Toxicity SP - 577 EP - 87 JF - Chinese journal of natural medicines JO - Chin J Nat Med VL - 11 IS - 6 N2 - The roots of Angelica sinensis (RAS), are a Chinese herbal medicine traditionally used in prescriptions for replenishing blood, treating abnormal menstruation, and other women's diseases. It has also been widely marketed as health food for women's care in Asia, and as a dietary supplement in Europe and America. RAS is well-known for its hematopoietic, antioxidant, and immunoregulatory activities. RAS also possesses anti-cancer, memory, radioprotective, and neuroprotective effects. Phytochemical investigations on this plant led to organic acids, phthalides, polysaccharides, and other metabolites. Based on recent animal studies and clinical trials, RAS has been used in the treatment of gynecologic diseases, cardio-cerebrovascular disease, nervous system diseases, and nephrotic syndrome. In this review, the recent phytochemical and pharmacological studies, drug-drug interactions, clinical applications, and toxicity of RAS are summarized. SN - 1875-5364 UR - https://www.unboundmedicine.com/medline/citation/24345498/Phytochemical_and_pharmacological_studies_on_Radix_Angelica_sinensis_ DB - PRIME DP - Unbound Medicine ER -