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Prevention of high altitude illness.
Travel Med Infect Dis. 2014 Jan-Feb; 12(1):29-39.TM

Abstract

High altitude illness - Acute Mountain Sickness (AMS), High Altitude Cerebral Edema (HACE) and High Altitude Pulmonary Edema (HAPE) - can be prevented or limited in severity by gradual ascent and by pharmacologic methods. The decision whether to use pharmacologic prophylaxis depends on the ascent rate and an individual's previous history of altitude illness. This review discusses risk stratification to determine whether to use pharmacologic prophylaxis and recommends specific drugs, especially acetazolamide, dexamethasone and nifedipine. This review also evaluates non-recommended drugs. In addition, this review suggests non-pharmacologic methods of decreasing the risk of severe altitude illness. There are also brief sections on how to decrease sleep disturbance at high altitude, travel to high altitude for patients with pre-existing illness and advice for travelers ascending to high altitude.

Authors+Show Affiliations

Department of Emergency Medicine, Alaska Native Medical Center, Anchorage, AK, USA; Division of Emergency Medicine, Stanford University Medical Center, Palo Alto, CA, USA; Himalayan Rescue Association, Kathmandu, Nepal; International Commission for Mountain Emergency Medicine (ICAR MEDCOM), USA. Electronic address: zafren@alaska.com.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24393671

Citation

Zafren, Ken. "Prevention of High Altitude Illness." Travel Medicine and Infectious Disease, vol. 12, no. 1, 2014, pp. 29-39.
Zafren K. Prevention of high altitude illness. Travel Med Infect Dis. 2014;12(1):29-39.
Zafren, K. (2014). Prevention of high altitude illness. Travel Medicine and Infectious Disease, 12(1), 29-39. https://doi.org/10.1016/j.tmaid.2013.12.002
Zafren K. Prevention of High Altitude Illness. Travel Med Infect Dis. 2014 Jan-Feb;12(1):29-39. PubMed PMID: 24393671.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevention of high altitude illness. A1 - Zafren,Ken, Y1 - 2013/12/22/ PY - 2013/10/11/received PY - 2013/12/05/revised PY - 2013/12/10/accepted PY - 2014/1/8/entrez PY - 2014/1/8/pubmed PY - 2014/9/30/medline KW - Acclimatization KW - Acute mountain sickness KW - High altitude KW - High altitude cerebral edema KW - High altitude pulmonary edema SP - 29 EP - 39 JF - Travel medicine and infectious disease JO - Travel Med Infect Dis VL - 12 IS - 1 N2 - High altitude illness - Acute Mountain Sickness (AMS), High Altitude Cerebral Edema (HACE) and High Altitude Pulmonary Edema (HAPE) - can be prevented or limited in severity by gradual ascent and by pharmacologic methods. The decision whether to use pharmacologic prophylaxis depends on the ascent rate and an individual's previous history of altitude illness. This review discusses risk stratification to determine whether to use pharmacologic prophylaxis and recommends specific drugs, especially acetazolamide, dexamethasone and nifedipine. This review also evaluates non-recommended drugs. In addition, this review suggests non-pharmacologic methods of decreasing the risk of severe altitude illness. There are also brief sections on how to decrease sleep disturbance at high altitude, travel to high altitude for patients with pre-existing illness and advice for travelers ascending to high altitude. SN - 1873-0442 UR - https://www.unboundmedicine.com/medline/citation/24393671/Prevention_of_high_altitude_illness_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1477-8939(13)00216-0 DB - PRIME DP - Unbound Medicine ER -
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