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Pd-catalyzed oxidative coupling of enamides and alkynes for synthesis of substituted pyrroles.
Org Lett. 2014 Jan 17; 16(2):608-11.OL

Abstract

A novel and efficient palladium(II)-catalyzed alkenyl C-H activation oxidative annulation of enamides with alkynes for the synthesis of substituted pyrroles has been developed. The reaction tolerates a wide range of functional groups and is a reliable method for the synthesis of triaryl-substituted pyrroles in high yields.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Zhao MN
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University , Xi'an 710069, P. R. China.
Ren ZH
No affiliation info available
Wang YY
No affiliation info available
Guan ZH
No affiliation info available

MeSH

AlkynesAmidesCatalysisCyclizationIndolesMolecular StructureOxidation-ReductionPalladiumPyrrolesStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24404972

Citation

Zhao, Mi-Na, et al. "Pd-catalyzed Oxidative Coupling of Enamides and Alkynes for Synthesis of Substituted Pyrroles." Organic Letters, vol. 16, no. 2, 2014, pp. 608-11.
Zhao MN, Ren ZH, Wang YY, et al. Pd-catalyzed oxidative coupling of enamides and alkynes for synthesis of substituted pyrroles. Org Lett. 2014;16(2):608-11.
Zhao, M. N., Ren, Z. H., Wang, Y. Y., & Guan, Z. H. (2014). Pd-catalyzed oxidative coupling of enamides and alkynes for synthesis of substituted pyrroles. Organic Letters, 16(2), 608-11. https://doi.org/10.1021/ol403517p
Zhao MN, et al. Pd-catalyzed Oxidative Coupling of Enamides and Alkynes for Synthesis of Substituted Pyrroles. Org Lett. 2014 Jan 17;16(2):608-11. PubMed PMID: 24404972.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pd-catalyzed oxidative coupling of enamides and alkynes for synthesis of substituted pyrroles. AU - Zhao,Mi-Na, AU - Ren,Zhi-Hui, AU - Wang,Yao-Yu, AU - Guan,Zheng-Hui, Y1 - 2014/01/09/ PY - 2014/1/11/entrez PY - 2014/1/11/pubmed PY - 2014/7/30/medline SP - 608 EP - 11 JF - Organic letters JO - Org Lett VL - 16 IS - 2 N2 - A novel and efficient palladium(II)-catalyzed alkenyl C-H activation oxidative annulation of enamides with alkynes for the synthesis of substituted pyrroles has been developed. The reaction tolerates a wide range of functional groups and is a reliable method for the synthesis of triaryl-substituted pyrroles in high yields. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/24404972/Pd_catalyzed_oxidative_coupling_of_enamides_and_alkynes_for_synthesis_of_substituted_pyrroles_ DB - PRIME DP - Unbound Medicine ER -