Tags

Type your tag names separated by a space and hit enter

Analysis of the influenza A (H1N1) 2009 pandemic infection in Japanese asthmatic patients: using a questionnaire-based survey.
Allergol Int. 2014 Mar; 63(1):67-74.AI

Abstract

BACKGROUND

Influenza infection is known to be an exacerbating factor in the control of asthma, therfore its prevention is critical in managing asthma. The aim of this study was to investigate the influenza A H1N1 2009 pandemic virus (H1N1 pdm09) infection in adult asthmatic patients.

METHODS

Data were obtained from a questionnaire-based survey of asthmatic patients conducted from September to October 2010 in Niigata Prefecture. Patient background, H1N1 pdm09 infection, vaccination status, and asthma exacerbation due to influenza infection were analyzed.

RESULTS

In total, 2,555 cases were analyzed. The incidence of the infection was 6.7% (95% confidence interval [CI]: 5.7-7.6), and the rate of vaccination was 63.9% (95% CI: 62.1-65.8). The odds ratio (OR) for vaccination against the infection among adult patients and younger patients (≤ the median age) were 0.61 (95% CI: 0.45-0.84) and 0.62 (95% CI: 0.42-0.90), respectively. However, OR among the older patient (> median age) were 1.38 (95%CI: 0.66-2.89). The rate of infection-induced asthma exacerbation was 23.2% (95% CI: 18.6-29.6), and the OR for vaccination against the infection-induced asthma exacerbation was 1.42 (95% CI: 0.69-2.92).

CONCLUSIONS

The effectiveness of the vaccination against the H1N1 pdm09 virus was confirmed during the first pandemic season, but it was limited. Further investigation on H1N1 pdm09 virus infection in asthmatics will be required.

Authors+Show Affiliations

Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Department of General Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.Department of Medicine, Prefectural Muikamachi Hospital, Niigata, Japan.Division of Infection Control and Prevention, Niigata University Medical and Dental Hospital, Niigata, Japan.Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Department of Respiratory Disease, Niigata Citizen Hospital, Niigata, Japan.Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.Department of General Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24457814

Citation

Koshio, Nao, et al. "Analysis of the Influenza a (H1N1) 2009 Pandemic Infection in Japanese Asthmatic Patients: Using a Questionnaire-based Survey." Allergology International : Official Journal of the Japanese Society of Allergology, vol. 63, no. 1, 2014, pp. 67-74.
Koshio N, Hasegawa T, Suzuki K, et al. Analysis of the influenza A (H1N1) 2009 pandemic infection in Japanese asthmatic patients: using a questionnaire-based survey. Allergol Int. 2014;63(1):67-74.
Koshio, N., Hasegawa, T., Suzuki, K., Tanabe, Y., Koya, T., Sakagami, T., Aoki, N., Hoshino, Y., Kagamu, H., Tsukada, H., Arakawa, M., Gejyo, F., Narita, I., & Suzuki, E. (2014). Analysis of the influenza A (H1N1) 2009 pandemic infection in Japanese asthmatic patients: using a questionnaire-based survey. Allergology International : Official Journal of the Japanese Society of Allergology, 63(1), 67-74. https://doi.org/10.2332/allergolint.13-OA-0609
Koshio N, et al. Analysis of the Influenza a (H1N1) 2009 Pandemic Infection in Japanese Asthmatic Patients: Using a Questionnaire-based Survey. Allergol Int. 2014;63(1):67-74. PubMed PMID: 24457814.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Analysis of the influenza A (H1N1) 2009 pandemic infection in Japanese asthmatic patients: using a questionnaire-based survey. AU - Koshio,Nao, AU - Hasegawa,Takashi, AU - Suzuki,Kazuo, AU - Tanabe,Yoshinari, AU - Koya,Toshiyuki, AU - Sakagami,Takuro, AU - Aoki,Nobumasa, AU - Hoshino,Yoshifumi, AU - Kagamu,Hiroshi, AU - Tsukada,Hiroki, AU - Arakawa,Masaaki, AU - Gejyo,Fumitake, AU - Narita,Ichiei, AU - Suzuki,Eiichi, AU - ,, PY - 2013/07/29/received PY - 2013/09/09/accepted PY - 2014/1/25/entrez PY - 2014/1/25/pubmed PY - 2014/10/29/medline SP - 67 EP - 74 JF - Allergology international : official journal of the Japanese Society of Allergology JO - Allergol Int VL - 63 IS - 1 N2 - BACKGROUND: Influenza infection is known to be an exacerbating factor in the control of asthma, therfore its prevention is critical in managing asthma. The aim of this study was to investigate the influenza A H1N1 2009 pandemic virus (H1N1 pdm09) infection in adult asthmatic patients. METHODS: Data were obtained from a questionnaire-based survey of asthmatic patients conducted from September to October 2010 in Niigata Prefecture. Patient background, H1N1 pdm09 infection, vaccination status, and asthma exacerbation due to influenza infection were analyzed. RESULTS: In total, 2,555 cases were analyzed. The incidence of the infection was 6.7% (95% confidence interval [CI]: 5.7-7.6), and the rate of vaccination was 63.9% (95% CI: 62.1-65.8). The odds ratio (OR) for vaccination against the infection among adult patients and younger patients (≤ the median age) were 0.61 (95% CI: 0.45-0.84) and 0.62 (95% CI: 0.42-0.90), respectively. However, OR among the older patient (> median age) were 1.38 (95%CI: 0.66-2.89). The rate of infection-induced asthma exacerbation was 23.2% (95% CI: 18.6-29.6), and the OR for vaccination against the infection-induced asthma exacerbation was 1.42 (95% CI: 0.69-2.92). CONCLUSIONS: The effectiveness of the vaccination against the H1N1 pdm09 virus was confirmed during the first pandemic season, but it was limited. Further investigation on H1N1 pdm09 virus infection in asthmatics will be required. SN - 1440-1592 UR - https://www.unboundmedicine.com/medline/citation/24457814/Analysis_of_the_influenza_A__H1N1__2009_pandemic_infection_in_Japanese_asthmatic_patients:_using_a_questionnaire_based_survey_ L2 - https://linkinghub.elsevier.com/retrieve/pii/063010067 DB - PRIME DP - Unbound Medicine ER -