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Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus.
Am J Infect Control. 2014 Mar; 42(3):265-70.AJ

Abstract

BACKGROUND

Decontamination, cleaning, and reuse of filtering facepiece respirators (FFRs) has been proposed to mitigate an acute FFR shortage during a public health emergency. Our study evaluates the ability of commercially available wipe products to clean FFRs contaminated with either infectious or noninfectious aerosols.

METHODS

Three models of surgical N95 FFRs were contaminated with aerosols of mucin or viable Staphylococcus aureus then cleaned with hypochlorite, benzalkonium chloride, or nonantimicrobial wipes. After cleaning, FFRs were separated into components (nose pad, fabrics, and perforated strip), and contaminants were extracted and quantified. Filtration performance was assessed for cleaned FFRs.

RESULTS

Mucin removal was <1 log for all wipe products on all components. Inert wipes achieved ∼1-log attenuation in viable S aureus on fabrics from all FFR models--removal was less effective from nose pads and perforated edges. Both antimicrobial wipes achieved 3-5-log attenuation on most components, with smaller reductions on nose pads and greater reductions on perforated strips. Particle penetration following cleaning yielded mean values <5%. The highest penetrations were observed in FFRs cleaned with benzalkonium chloride wipes.

CONCLUSIONS

FFRs can be disinfected using antimicrobial wipe products, but not effectively cleaned with the wipes evaluated in this study. This study provides informative data for the development of better FFRs and applicable cleaning products.

Authors+Show Affiliations

Applied Research Associates, Panama City, FL. Electronic address: bheimb44@gmail.com.Applied Research Associates, Panama City, FL.Applied Research Associates, Panama City, FL.Applied Research Associates, Panama City, FL.National Institute for Occupational Safety and Health, Pittsburgh, PA.Air Force Research Laboratory, Tyndall Air Force Base, FL.

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

24462175

Citation

Heimbuch, Brian K., et al. "Cleaning of Filtering Facepiece Respirators Contaminated With Mucin and Staphylococcus Aureus." American Journal of Infection Control, vol. 42, no. 3, 2014, pp. 265-70.
Heimbuch BK, Kinney K, Lumley AE, et al. Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus. Am J Infect Control. 2014;42(3):265-70.
Heimbuch, B. K., Kinney, K., Lumley, A. E., Harnish, D. A., Bergman, M., & Wander, J. D. (2014). Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus. American Journal of Infection Control, 42(3), 265-70. https://doi.org/10.1016/j.ajic.2013.09.014
Heimbuch BK, et al. Cleaning of Filtering Facepiece Respirators Contaminated With Mucin and Staphylococcus Aureus. Am J Infect Control. 2014;42(3):265-70. PubMed PMID: 24462175.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cleaning of filtering facepiece respirators contaminated with mucin and Staphylococcus aureus. AU - Heimbuch,Brian K, AU - Kinney,Kimberly, AU - Lumley,April E, AU - Harnish,Delbert A, AU - Bergman,Michael, AU - Wander,Joseph D, Y1 - 2014/01/23/ PY - 2013/05/03/received PY - 2013/09/06/revised PY - 2013/09/09/accepted PY - 2014/1/28/entrez PY - 2014/1/28/pubmed PY - 2014/10/18/medline KW - Aerosol KW - Bioaerosol KW - Decontamination KW - Influenza KW - Pandemic KW - Saliva SP - 265 EP - 70 JF - American journal of infection control JO - Am J Infect Control VL - 42 IS - 3 N2 - BACKGROUND: Decontamination, cleaning, and reuse of filtering facepiece respirators (FFRs) has been proposed to mitigate an acute FFR shortage during a public health emergency. Our study evaluates the ability of commercially available wipe products to clean FFRs contaminated with either infectious or noninfectious aerosols. METHODS: Three models of surgical N95 FFRs were contaminated with aerosols of mucin or viable Staphylococcus aureus then cleaned with hypochlorite, benzalkonium chloride, or nonantimicrobial wipes. After cleaning, FFRs were separated into components (nose pad, fabrics, and perforated strip), and contaminants were extracted and quantified. Filtration performance was assessed for cleaned FFRs. RESULTS: Mucin removal was <1 log for all wipe products on all components. Inert wipes achieved ∼1-log attenuation in viable S aureus on fabrics from all FFR models--removal was less effective from nose pads and perforated edges. Both antimicrobial wipes achieved 3-5-log attenuation on most components, with smaller reductions on nose pads and greater reductions on perforated strips. Particle penetration following cleaning yielded mean values <5%. The highest penetrations were observed in FFRs cleaned with benzalkonium chloride wipes. CONCLUSIONS: FFRs can be disinfected using antimicrobial wipe products, but not effectively cleaned with the wipes evaluated in this study. This study provides informative data for the development of better FFRs and applicable cleaning products. SN - 1527-3296 UR - https://www.unboundmedicine.com/medline/citation/24462175/Cleaning_of_filtering_facepiece_respirators_contaminated_with_mucin_and_Staphylococcus_aureus_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0196-6553(13)01296-0 DB - PRIME DP - Unbound Medicine ER -