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Performance of an automated six-wavelength photometer (Radiometer OSM3) for routine measurement of hemoglobin derivatives.
Clin Chem. 1988 Jan; 34(1):149-52.CC

Abstract

A new instrument for spectrophotometric determination of oxygen saturation (SO2) and the fractions of carboxyhemoglobin (FHbCO) and methemoglobin (FHi), the Hemoximeter OSM3 (Radiometer), was tested by comparative measurements with a multiwavelength method. We found that it gave reliable results for freshly drawn samples from patients. When samples with artificially induced high proportions of HbCO or Hi, or both, were introduced, results were still sufficiently accurate. The presence of sulfhemoglobin (SHb) seriously interfered with the measurement of SO2, FHbCO, and FHi, but the instrument reliably indicated its presence. Because SHb is rarely encountered, a reliable warning for its presence is adequate for clinical practice. Using the instrument in its fetal mode, we obtained accurate results for blood samples from newborns.

Authors+Show Affiliations

Zijlstra WG
Department of Physiology, University of Groningen, The Netherlands.
Buursma A
No affiliation info available
Zwart A
No affiliation info available

MeSH

AdultCarboxyhemoglobinFetal BloodFetal HemoglobinHemoglobinsHumansMethemoglobinOxygenQuality ControlRegression AnalysisSpectrophotometrySulfhemoglobin

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

2448064

Citation

Zijlstra, W G., et al. "Performance of an Automated Six-wavelength Photometer (Radiometer OSM3) for Routine Measurement of Hemoglobin Derivatives." Clinical Chemistry, vol. 34, no. 1, 1988, pp. 149-52.
Zijlstra WG, Buursma A, Zwart A. Performance of an automated six-wavelength photometer (Radiometer OSM3) for routine measurement of hemoglobin derivatives. Clin Chem. 1988;34(1):149-52.
Zijlstra, W. G., Buursma, A., & Zwart, A. (1988). Performance of an automated six-wavelength photometer (Radiometer OSM3) for routine measurement of hemoglobin derivatives. Clinical Chemistry, 34(1), 149-52.
Zijlstra WG, Buursma A, Zwart A. Performance of an Automated Six-wavelength Photometer (Radiometer OSM3) for Routine Measurement of Hemoglobin Derivatives. Clin Chem. 1988;34(1):149-52. PubMed PMID: 2448064.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Performance of an automated six-wavelength photometer (Radiometer OSM3) for routine measurement of hemoglobin derivatives. AU - Zijlstra,W G, AU - Buursma,A, AU - Zwart,A, PY - 1988/1/1/pubmed PY - 1988/1/1/medline PY - 1988/1/1/entrez SP - 149 EP - 52 JF - Clinical chemistry JO - Clin Chem VL - 34 IS - 1 N2 - A new instrument for spectrophotometric determination of oxygen saturation (SO2) and the fractions of carboxyhemoglobin (FHbCO) and methemoglobin (FHi), the Hemoximeter OSM3 (Radiometer), was tested by comparative measurements with a multiwavelength method. We found that it gave reliable results for freshly drawn samples from patients. When samples with artificially induced high proportions of HbCO or Hi, or both, were introduced, results were still sufficiently accurate. The presence of sulfhemoglobin (SHb) seriously interfered with the measurement of SO2, FHbCO, and FHi, but the instrument reliably indicated its presence. Because SHb is rarely encountered, a reliable warning for its presence is adequate for clinical practice. Using the instrument in its fetal mode, we obtained accurate results for blood samples from newborns. SN - 0009-9147 UR - https://www.unboundmedicine.com/medline/citation/2448064/Performance_of_an_automated_six_wavelength_photometer__Radiometer_OSM3__for_routine_measurement_of_hemoglobin_derivatives_ DB - PRIME DP - Unbound Medicine ER -