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Bone mineral density in patients with inflammatory bowel disease from north-eastern Romania.
Rev Med Chir Soc Med Nat Iasi 2013 Jan-Mar; 117(1):23-8RM

Abstract

Inflammatory bowel disease (IBD) is associated with increased prevalence of bone demineralization. One of the risk factors for low bone density is the inadequate level of 25-OH vitamin D.

AIM

To determine the degree of bone demineralization in patients with IBD and the main causes leading to this condition.

MATERIAL AND METHODS

A prospective study was carried out between April, 2011 and October, 2012 in 143 patients diagnosed with IBD at the Gastroenterology and Hepatology Centre of Iaşi.The IBD diagnosis was made on clinical, biological, and endoscopic criteria and confirmed histologically. The diagnosis of osteopenia/osteoporosis was based on World Health Organization criteria.

RESULTS

Osteopenia was found in 48.07% of the patients with ulcerative colits (UC) and in 56.41% of the patients with Crohn's disease (CD); osteoporosis was present in 18.26% of the patients with UC and 15.38% of those with CD. The main causes identified were inadequate vitamin D level, extended high-dose corticotherapy in patients with CD, BMI < 18.5 kg/m2, and smoking, especially in the patients with UC.

CONCLUSIONS

Bone demineralization and hypovitaminosis D are frequently associated with IBD and require specific treatment.

Authors+Show Affiliations

Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa, Iasi.Discipline of Medical Semiology, IGH, Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa, Iasi.Discipline of Medical Semiology, IGH, Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa, Iasi.Discipline of Medical Semiology, IGH, Faculty of Medicine, University of Medicine and Pharmacy Grigore T. Popa, Iasi.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24505888

Citation

Dumitrescu, Gabriela, et al. "Bone Mineral Density in Patients With Inflammatory Bowel Disease From North-eastern Romania." Revista Medico-chirurgicala a Societatii De Medici Si Naturalisti Din Iasi, vol. 117, no. 1, 2013, pp. 23-8.
Dumitrescu G, Mihai C, Dranga M, et al. Bone mineral density in patients with inflammatory bowel disease from north-eastern Romania. Rev Med Chir Soc Med Nat Iasi. 2013;117(1):23-8.
Dumitrescu, G., Mihai, C., Dranga, M., & Prelipcean, C. C. (2013). Bone mineral density in patients with inflammatory bowel disease from north-eastern Romania. Revista Medico-chirurgicala a Societatii De Medici Si Naturalisti Din Iasi, 117(1), pp. 23-8.
Dumitrescu G, et al. Bone Mineral Density in Patients With Inflammatory Bowel Disease From North-eastern Romania. Rev Med Chir Soc Med Nat Iasi. 2013;117(1):23-8. PubMed PMID: 24505888.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bone mineral density in patients with inflammatory bowel disease from north-eastern Romania. AU - Dumitrescu,Gabriela, AU - Mihai,Cătălina, AU - Dranga,Mihaela, AU - Prelipcean,Cristina Cijevschi, PY - 2014/2/11/entrez PY - 2014/2/11/pubmed PY - 2014/3/25/medline SP - 23 EP - 8 JF - Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi JO - Rev Med Chir Soc Med Nat Iasi VL - 117 IS - 1 N2 - UNLABELLED: Inflammatory bowel disease (IBD) is associated with increased prevalence of bone demineralization. One of the risk factors for low bone density is the inadequate level of 25-OH vitamin D. AIM: To determine the degree of bone demineralization in patients with IBD and the main causes leading to this condition. MATERIAL AND METHODS: A prospective study was carried out between April, 2011 and October, 2012 in 143 patients diagnosed with IBD at the Gastroenterology and Hepatology Centre of Iaşi.The IBD diagnosis was made on clinical, biological, and endoscopic criteria and confirmed histologically. The diagnosis of osteopenia/osteoporosis was based on World Health Organization criteria. RESULTS: Osteopenia was found in 48.07% of the patients with ulcerative colits (UC) and in 56.41% of the patients with Crohn's disease (CD); osteoporosis was present in 18.26% of the patients with UC and 15.38% of those with CD. The main causes identified were inadequate vitamin D level, extended high-dose corticotherapy in patients with CD, BMI < 18.5 kg/m2, and smoking, especially in the patients with UC. CONCLUSIONS: Bone demineralization and hypovitaminosis D are frequently associated with IBD and require specific treatment. SN - 0048-7848 UR - https://www.unboundmedicine.com/medline/citation/24505888/Bone_mineral_density_in_patients_with_inflammatory_bowel_disease_from_north_eastern_Romania_ L2 - https://medlineplus.gov/bonedensity.html DB - PRIME DP - Unbound Medicine ER -