Tags

Type your tag names separated by a space and hit enter

Risk of subsequent dementia in patients with hypertensive encephalopathy: a nationwide population-based study in Taiwan.
Dement Geriatr Cogn Disord. 2014; 37(5-6):357-65.DG

Abstract

BACKGROUND/AIMS

We investigated the association of hypertensive encephalopathy (HE) with subsequent dementia.

METHODS

Using universal insurance claims data, we identified a study cohort of 5,504 participants with HE newly diagnosed between 1997 and 2010 and a comparison cohort of 22,016 healthy participants. Incidence and risks of dementia were estimated for both cohorts until the end of 2010.

RESULTS

The dementia incidence was 1.45-fold [95% confidence interval (CI) = 1.27-1.66] higher in the study cohort than in the comparison cohort, with an adjusted hazard ratio (HR) of 1.38 (95% CI = 1.19-1.59) for the study cohort. The risk was higher for males than for females and elderly patients. With an incidence of 13.4 per 1,000 person-years, the HR of dementia increased to 2.09 (95% CI = 1.18-3.71) for the HE patients with the comorbidities of head injury and diabetes compared to those without HE and comorbidities. The risk of developing dementia declined with the follow-up time.

CONCLUSION

Hypertensive patients with HE displayed a significantly higher risk for dementia than those without HE. The risk increased further in those with the comorbidities of head injury and diabetes. Physicians should be aware of the link between HE and dementia when assessing patients with HE.

Authors+Show Affiliations

Department of Neurology, China Medical University Hospital, Taichung, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24513673

Citation

Huang, Wei-Shih, et al. "Risk of Subsequent Dementia in Patients With Hypertensive Encephalopathy: a Nationwide Population-based Study in Taiwan." Dementia and Geriatric Cognitive Disorders, vol. 37, no. 5-6, 2014, pp. 357-65.
Huang WS, Tseng CH, Lin CL, et al. Risk of subsequent dementia in patients with hypertensive encephalopathy: a nationwide population-based study in Taiwan. Dement Geriatr Cogn Disord. 2014;37(5-6):357-65.
Huang, W. S., Tseng, C. H., Lin, C. L., Lin, C. Y., Sung, F. C., & Kao, C. H. (2014). Risk of subsequent dementia in patients with hypertensive encephalopathy: a nationwide population-based study in Taiwan. Dementia and Geriatric Cognitive Disorders, 37(5-6), 357-65. https://doi.org/10.1159/000357701
Huang WS, et al. Risk of Subsequent Dementia in Patients With Hypertensive Encephalopathy: a Nationwide Population-based Study in Taiwan. Dement Geriatr Cogn Disord. 2014;37(5-6):357-65. PubMed PMID: 24513673.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk of subsequent dementia in patients with hypertensive encephalopathy: a nationwide population-based study in Taiwan. AU - Huang,Wei-Shih, AU - Tseng,Chun-Hung, AU - Lin,Cheng-Li, AU - Lin,Chi-Yu, AU - Sung,Fung-Chang, AU - Kao,Chia-Hung, Y1 - 2014/02/08/ PY - 2013/12/03/accepted PY - 2014/2/12/entrez PY - 2014/2/12/pubmed PY - 2015/2/3/medline SP - 357 EP - 65 JF - Dementia and geriatric cognitive disorders JO - Dement Geriatr Cogn Disord VL - 37 IS - 5-6 N2 - BACKGROUND/AIMS: We investigated the association of hypertensive encephalopathy (HE) with subsequent dementia. METHODS: Using universal insurance claims data, we identified a study cohort of 5,504 participants with HE newly diagnosed between 1997 and 2010 and a comparison cohort of 22,016 healthy participants. Incidence and risks of dementia were estimated for both cohorts until the end of 2010. RESULTS: The dementia incidence was 1.45-fold [95% confidence interval (CI) = 1.27-1.66] higher in the study cohort than in the comparison cohort, with an adjusted hazard ratio (HR) of 1.38 (95% CI = 1.19-1.59) for the study cohort. The risk was higher for males than for females and elderly patients. With an incidence of 13.4 per 1,000 person-years, the HR of dementia increased to 2.09 (95% CI = 1.18-3.71) for the HE patients with the comorbidities of head injury and diabetes compared to those without HE and comorbidities. The risk of developing dementia declined with the follow-up time. CONCLUSION: Hypertensive patients with HE displayed a significantly higher risk for dementia than those without HE. The risk increased further in those with the comorbidities of head injury and diabetes. Physicians should be aware of the link between HE and dementia when assessing patients with HE. SN - 1421-9824 UR - https://www.unboundmedicine.com/medline/citation/24513673/Risk_of_subsequent_dementia_in_patients_with_hypertensive_encephalopathy:_a_nationwide_population_based_study_in_Taiwan_ L2 - https://www.karger.com?DOI=10.1159/000357701 DB - PRIME DP - Unbound Medicine ER -