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[Cluster analysis on TCM syndrome characteristics of chronic hepatitis B].
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Jan; 34(1):39-42.ZZ

Abstract

OBJECTIVE

To explore the characteristics of Chinese medicine (CM) syndromes of chronic hepatitis B (CHB) in Sichuan area, thus providing referential evidence for objective research of CHB.

METHODS

According to the CRF chart, 1 064 CHB patients' four diagnostic information from 8 clinical units were recorded in Sichuan region using cross-sectional method. The laws of CHB syndrome characteristics were explored using the K-means clustering analysis method.

RESULTS

Based on the K-means cluster analysis, we found 8 categories that fulfill the clinical practice combined professional knowledge with experts' opinions. They were Pi-Wei dampness heat (326 cases, 30.6%), Gan and gallbladder dampness heat (193 cases, 18.1%), Gan and Pi dampness heat (158 cases, 14.8%), Gan depression and Pi deficiency (92 cases, 8.6%), Gan depression transforming into heat (89 cases, 8.4%), Pi deficiency with dampness encumbrance (74 cases, 7.0%), dampness-heat combined with yin deficiency of Gan and Shen (73 cases, 6.9%), yang deficiency mingled with blood stasis (59 cases, 5.5%).

CONCLUSION

The results of cluster analysis showed Pi-Wei dampness heat, Gan and gallbladder dampness heat, Gan and Pi dampness heat, Gan depression and Pi deficiency, Gan depression transforming into heat, Pi deficiency with dampness encumbrance, dampness-heat combined with yin deficiency of Gan and Shen, yang deficiency mingled with blood stasis were mainly syndromes of CHB patients in Sichuan area.

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Authors+Show Affiliations

Wang EC
Department of Liver and Gallbladder Diseases, Affiliated Hospital of TCM, Luzhou Medical College, Sichuan 646000, China.
Tang L
Department of Gynecology and Obstetrics, Affiliated Hospital of TCM, Luzhou Medical College, Sichuan 646000, China.
Wang J
Department of Gastroenterology, Bixian TCM Hospital, Sichuan 611730, China.
Zhang L
Basic Medical College, Chengdu University of TCM,Chengdu 610075, China.
Cao CH
Basic Medical College, Chengdu University of TCM,Chengdu 610075, China.
Feng QS
Basic Medical College, Chengdu University of TCM,Chengdu 610075, China.

MeSH

AdolescentAdultAgedCluster AnalysisCross-Sectional StudiesFemaleHepatitis B, ChronicHumansMaleMedicine, Chinese TraditionalMiddle AgedYang DeficiencyYin DeficiencyYoung Adult

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

24520785

Citation

Wang, En-Cheng, et al. "[Cluster Analysis On TCM Syndrome Characteristics of Chronic Hepatitis B]." Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine, vol. 34, no. 1, 2014, pp. 39-42.
Wang EC, Tang L, Wang J, et al. [Cluster analysis on TCM syndrome characteristics of chronic hepatitis B]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014;34(1):39-42.
Wang, E. C., Tang, L., Wang, J., Zhang, L., Cao, C. H., & Feng, Q. S. (2014). [Cluster analysis on TCM syndrome characteristics of chronic hepatitis B]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine, 34(1), 39-42.
Wang EC, et al. [Cluster Analysis On TCM Syndrome Characteristics of Chronic Hepatitis B]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014;34(1):39-42. PubMed PMID: 24520785.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Cluster analysis on TCM syndrome characteristics of chronic hepatitis B]. AU - Wang,En-Cheng, AU - Tang,Lin, AU - Wang,Jian, AU - Zhang,Lei, AU - Cao,Chun-Hui, AU - Feng,Quan-Sheng, PY - 2014/2/14/entrez PY - 2014/2/14/pubmed PY - 2015/1/6/medline SP - 39 EP - 42 JF - Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine JO - Zhongguo Zhong Xi Yi Jie He Za Zhi VL - 34 IS - 1 N2 - OBJECTIVE: To explore the characteristics of Chinese medicine (CM) syndromes of chronic hepatitis B (CHB) in Sichuan area, thus providing referential evidence for objective research of CHB. METHODS: According to the CRF chart, 1 064 CHB patients' four diagnostic information from 8 clinical units were recorded in Sichuan region using cross-sectional method. The laws of CHB syndrome characteristics were explored using the K-means clustering analysis method. RESULTS: Based on the K-means cluster analysis, we found 8 categories that fulfill the clinical practice combined professional knowledge with experts' opinions. They were Pi-Wei dampness heat (326 cases, 30.6%), Gan and gallbladder dampness heat (193 cases, 18.1%), Gan and Pi dampness heat (158 cases, 14.8%), Gan depression and Pi deficiency (92 cases, 8.6%), Gan depression transforming into heat (89 cases, 8.4%), Pi deficiency with dampness encumbrance (74 cases, 7.0%), dampness-heat combined with yin deficiency of Gan and Shen (73 cases, 6.9%), yang deficiency mingled with blood stasis (59 cases, 5.5%). CONCLUSION: The results of cluster analysis showed Pi-Wei dampness heat, Gan and gallbladder dampness heat, Gan and Pi dampness heat, Gan depression and Pi deficiency, Gan depression transforming into heat, Pi deficiency with dampness encumbrance, dampness-heat combined with yin deficiency of Gan and Shen, yang deficiency mingled with blood stasis were mainly syndromes of CHB patients in Sichuan area. SN - 1003-5370 UR - https://www.unboundmedicine.com/medline/citation/24520785/[Cluster_analysis_on_TCM_syndrome_characteristics_of_chronic_hepatitis_B]_ L2 - http://www.diseaseinfosearch.org/result/3332 DB - PRIME DP - Unbound Medicine ER -