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Serum albumin, retinol-binding protein, thyroxin-binding prealbumin and acute phase reactants as indicators of undernutrition in children with undue susceptibility to acute infections.
Acta Paediatr Scand. 1988 Jan; 77(1):94-8.AP

Abstract

This study was conducted in order to test the usefulness of measuring the concentrations of selected serum proteins and acute phase reactants in assessing the nutritional status of children with undue susceptibility to acute infections. The concentrations of serum proteins were determined by an immunodiffusion technique in 28 children with undue susceptibility to infections and were compared with those in healthy children. The patients were grouped according to the clinical pattern, i.e. into children with mainly upper respiratory tract infections, with frequent middle ear infections and with lower respiratory tract infections. The total group and all three subgroups of patients had not only significantly lower (p less than 0.001 or p less than 0.01) mean serum levels of albumin and retinol-binding protein, but also of the acute phase reactants alpha 2-macroglobulin and ceruloplasmin (p less than 0.01) than the controls. No differences were observed between the patients and the controls in respect of the acute phase reactant orosomucoid. This study indicates that the concentrations of albumin and RBP along with selected acute phase reactants are rapidly influenced by altered nutritional status in children with undue susceptibility to acute infections.

Authors+Show Affiliations

Department of Paediatrics, University Hospital, Uppsala, Sweden.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2453106

Citation

Bondestam, M, et al. "Serum Albumin, Retinol-binding Protein, Thyroxin-binding Prealbumin and Acute Phase Reactants as Indicators of Undernutrition in Children With Undue Susceptibility to Acute Infections." Acta Paediatrica Scandinavica, vol. 77, no. 1, 1988, pp. 94-8.
Bondestam M, Foucard T, Gebre-Medhin M. Serum albumin, retinol-binding protein, thyroxin-binding prealbumin and acute phase reactants as indicators of undernutrition in children with undue susceptibility to acute infections. Acta Paediatr Scand. 1988;77(1):94-8.
Bondestam, M., Foucard, T., & Gebre-Medhin, M. (1988). Serum albumin, retinol-binding protein, thyroxin-binding prealbumin and acute phase reactants as indicators of undernutrition in children with undue susceptibility to acute infections. Acta Paediatrica Scandinavica, 77(1), 94-8.
Bondestam M, Foucard T, Gebre-Medhin M. Serum Albumin, Retinol-binding Protein, Thyroxin-binding Prealbumin and Acute Phase Reactants as Indicators of Undernutrition in Children With Undue Susceptibility to Acute Infections. Acta Paediatr Scand. 1988;77(1):94-8. PubMed PMID: 2453106.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum albumin, retinol-binding protein, thyroxin-binding prealbumin and acute phase reactants as indicators of undernutrition in children with undue susceptibility to acute infections. AU - Bondestam,M, AU - Foucard,T, AU - Gebre-Medhin,M, PY - 1988/1/1/pubmed PY - 1988/1/1/medline PY - 1988/1/1/entrez SP - 94 EP - 8 JF - Acta paediatrica Scandinavica JO - Acta Paediatr Scand VL - 77 IS - 1 N2 - This study was conducted in order to test the usefulness of measuring the concentrations of selected serum proteins and acute phase reactants in assessing the nutritional status of children with undue susceptibility to acute infections. The concentrations of serum proteins were determined by an immunodiffusion technique in 28 children with undue susceptibility to infections and were compared with those in healthy children. The patients were grouped according to the clinical pattern, i.e. into children with mainly upper respiratory tract infections, with frequent middle ear infections and with lower respiratory tract infections. The total group and all three subgroups of patients had not only significantly lower (p less than 0.001 or p less than 0.01) mean serum levels of albumin and retinol-binding protein, but also of the acute phase reactants alpha 2-macroglobulin and ceruloplasmin (p less than 0.01) than the controls. No differences were observed between the patients and the controls in respect of the acute phase reactant orosomucoid. This study indicates that the concentrations of albumin and RBP along with selected acute phase reactants are rapidly influenced by altered nutritional status in children with undue susceptibility to acute infections. SN - 0001-656X UR - https://www.unboundmedicine.com/medline/citation/2453106/Serum_albumin_retinol_binding_protein_thyroxin_binding_prealbumin_and_acute_phase_reactants_as_indicators_of_undernutrition_in_children_with_undue_susceptibility_to_acute_infections_ L2 - https://medlineplus.gov/nutrition.html DB - PRIME DP - Unbound Medicine ER -