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The classification and diagnostic criteria of ankylosing spondylitis.
J Autoimmun 2014 Feb-Mar; 48-49:128-33JA

Abstract

Ankylosing spondylitis is the prototype of immune-mediated inflammatory rheumatic diseases grouped under the term spondyloarthritis (SpA). An early diagnosis has now become increasingly important because effective therapies are available and anti-TNF drugs are even more effective if used in early stages of the disease. In ankylosing spondylitis, the 1984 modified New York criteria have been used widely in clinical studies and daily practice but are not applicable in early disease when the characteristic radiographic signs of sacroiliitis are not visible but active sacroiliitis is readily detectable by magnetic resonance imaging (MRI). Thus there has been a need for new classification or diagnostic criteria to identify inflammatory spondyloarthritis at early stage of the disease. This led to the concept of axial SpA to include the entire spectrum of patients with axial disease both, with and without radiographic damage. New classification criteria for the wider group of SpA have been proposed by ASAS (Assessment of Spondylo Arthritis International Society); and the patients are sub-grouped into (1) a predominantly axial disease, termed axial SpA including AS and non-radiographic axial SpA; (2) peripheral SpA. The clinical course and disease process of non-radiographic axial spondyloarthritis remains unclear. However the development of the SpA criteria by ASAS particularly for axial SpA, is an important step for early diagnosis and better management of these patients.

Authors+Show Affiliations

VA Sacramento Medical Center, Department of Veterans Affairs, Northern California Health Care System, Mather, CA, USA; Department of Medicine, Division of Rheumatology, Allergy and Clinical Immunology, School of Medicine, University of California, Davis, USA. Electronic address: sraychaudhuri@ucdavis.edu.Division of Arthritis & Rheumatic Diseases (OP09), Oregon Health & Science University, Portland, OR 97239, USA.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24534717

Citation

Raychaudhuri, Siba P., and Atul Deodhar. "The Classification and Diagnostic Criteria of Ankylosing Spondylitis." Journal of Autoimmunity, vol. 48-49, 2014, pp. 128-33.
Raychaudhuri SP, Deodhar A. The classification and diagnostic criteria of ankylosing spondylitis. J Autoimmun. 2014;48-49:128-33.
Raychaudhuri, S. P., & Deodhar, A. (2014). The classification and diagnostic criteria of ankylosing spondylitis. Journal of Autoimmunity, 48-49, pp. 128-33. doi:10.1016/j.jaut.2014.01.015.
Raychaudhuri SP, Deodhar A. The Classification and Diagnostic Criteria of Ankylosing Spondylitis. J Autoimmun. 2014;48-49:128-33. PubMed PMID: 24534717.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The classification and diagnostic criteria of ankylosing spondylitis. AU - Raychaudhuri,Siba P, AU - Deodhar,Atul, Y1 - 2014/02/16/ PY - 2013/10/07/received PY - 2013/11/13/accepted PY - 2014/2/19/entrez PY - 2014/2/19/pubmed PY - 2014/10/3/medline KW - Ankylosing spondylitis KW - Diagnosis KW - Diagnostic criteria KW - Spondyloarthropathy SP - 128 EP - 33 JF - Journal of autoimmunity JO - J. Autoimmun. VL - 48-49 N2 - Ankylosing spondylitis is the prototype of immune-mediated inflammatory rheumatic diseases grouped under the term spondyloarthritis (SpA). An early diagnosis has now become increasingly important because effective therapies are available and anti-TNF drugs are even more effective if used in early stages of the disease. In ankylosing spondylitis, the 1984 modified New York criteria have been used widely in clinical studies and daily practice but are not applicable in early disease when the characteristic radiographic signs of sacroiliitis are not visible but active sacroiliitis is readily detectable by magnetic resonance imaging (MRI). Thus there has been a need for new classification or diagnostic criteria to identify inflammatory spondyloarthritis at early stage of the disease. This led to the concept of axial SpA to include the entire spectrum of patients with axial disease both, with and without radiographic damage. New classification criteria for the wider group of SpA have been proposed by ASAS (Assessment of Spondylo Arthritis International Society); and the patients are sub-grouped into (1) a predominantly axial disease, termed axial SpA including AS and non-radiographic axial SpA; (2) peripheral SpA. The clinical course and disease process of non-radiographic axial spondyloarthritis remains unclear. However the development of the SpA criteria by ASAS particularly for axial SpA, is an important step for early diagnosis and better management of these patients. SN - 1095-9157 UR - https://www.unboundmedicine.com/medline/citation/24534717/The_classification_and_diagnostic_criteria_of_ankylosing_spondylitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0896-8411(14)00018-3 DB - PRIME DP - Unbound Medicine ER -