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Essential oil characterization of two Azorean Cryptomeria japonica populations and their biological evaluations.
Nat Prod Commun. 2013 Dec; 8(12):1785-90.NP

Abstract

Essential oils from foliage, bark and heartwood of Cryptomeriajaponica D. Don from Azores Archipelago (Portugal) were analyzed by GC and GC-MS. Two populations, of black and reddish heartwood color, were studied. The main compounds found in the foliage of both populations were alpha-pinene (9.6-29.5%), (+)-phyllocladene (3.5-26.5%), ent-kaur-16-ene (0.2-20.6%), sabinene (0.5-19.9%) and limonene (1.4-11.5%), with a large variation in individual compounds from each population. Heartwood oils were characterized by a high content of cubebol (2.8-39.9%) and epi-cubebol (4.1-26.9%) isomers, which were absent in the foliage. Elemol and eudesmol isomers were found in the foliage and heartwood oils, while (+)-phyllocladene was absent in heartwood. Black and reddish bark oils were composed of the diterpenes dehydroferruginol (1.9-5.1%) and ferruginol (2.6-11.5%), along with the sesquiterpenes delta-cadinene (10.4-15.9%), alpha-muurolene (3.3-5.4%), epi-zonarene (4.0-5.0%), cubenol (9.3-14.0%), tau-muurolol (4.8-10.7%), beta-eudesmol (3.0-9.9%), gamma-eudesmol (1.9-7.0%) and hedycariol (1.4-6.2%). Azorean C. japonica oils exhibited significant chemical differences compared with native plants from Asia. The essential oils showed moderate antimicrobial activity against the pathogenic fungus Cryptococcus neoformans and human pathogenic bacteria (especially against multidrug-resistant Mycobacterium tuberculosis). The antimicrobial activity of the essential oils may be attributed to compounds such as ent-kaur-16-ene, (+)-phyllocladene, ferruginol and elemol, which are present in different proportions within the complex oil mixture. These results suggest a potential use for C. japonica oils obtained from wood industry leftovers.

Authors+Show Affiliations

Moiteiro C
Universidade de Lisboa, Faculdade de Ciências, Departamento de Química e Bioquímica, Centro de Química e Bioquímica, Campo Grande, 1749-016 Lisboa, Portugal. cmmoiteiro@fc.ul.pt
Esteves T
Universidade de Lisboa, Faculdade de Ciências, Departamento de Química e Bioquímica, Centro de Química e Bioquímica, Campo Grande, 1749-016 Lisboa, Portugal.
Ramalho L
Laboratório Nacional de Energia e Geologia, LBA-Laboratório de Biocombustíveis e Ambiente, Estrada do Paço do Lumiar, 22, 1648-039 Lisboa, Portugal.
Rojas R
Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofia, Universidad Peruana Cayetano
Alvarez S
Heredia, Av. Honorio Delgado 430 Urb. Ingeniería S.MP. Lima 31, Perú
Zacchino S
Heredia, Av. Honorio Delgado 430 Urb. Ingeniería S.MP. Lima 31, Perú
Bragança H
lnstituto Nacional de Investigação Agrária e Veterinária I.P., Quinta do Marquês, 2780-159 Oeiras, Portugal.

MeSH

Antifungal AgentsAntitubercular AgentsAzoresCryptomeriaGas Chromatography-Mass SpectrometryHumansMicrobial Sensitivity TestsOils, Volatile

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24555299

Citation

Moiteiro, Cristina, et al. "Essential Oil Characterization of Two Azorean Cryptomeria Japonica Populations and Their Biological Evaluations." Natural Product Communications, vol. 8, no. 12, 2013, pp. 1785-90.
Moiteiro C, Esteves T, Ramalho L, et al. Essential oil characterization of two Azorean Cryptomeria japonica populations and their biological evaluations. Nat Prod Commun. 2013;8(12):1785-90.
Moiteiro, C., Esteves, T., Ramalho, L., Rojas, R., Alvarez, S., Zacchino, S., & Bragança, H. (2013). Essential oil characterization of two Azorean Cryptomeria japonica populations and their biological evaluations. Natural Product Communications, 8(12), 1785-90.
Moiteiro C, et al. Essential Oil Characterization of Two Azorean Cryptomeria Japonica Populations and Their Biological Evaluations. Nat Prod Commun. 2013;8(12):1785-90. PubMed PMID: 24555299.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Essential oil characterization of two Azorean Cryptomeria japonica populations and their biological evaluations. AU - Moiteiro,Cristina, AU - Esteves,Teresa, AU - Ramalho,Luís, AU - Rojas,Rosario, AU - Alvarez,Sandra, AU - Zacchino,Susana, AU - Bragança,Helena, PY - 2014/2/22/entrez PY - 2014/2/22/pubmed PY - 2014/3/25/medline SP - 1785 EP - 90 JF - Natural product communications JO - Nat Prod Commun VL - 8 IS - 12 N2 - Essential oils from foliage, bark and heartwood of Cryptomeriajaponica D. Don from Azores Archipelago (Portugal) were analyzed by GC and GC-MS. Two populations, of black and reddish heartwood color, were studied. The main compounds found in the foliage of both populations were alpha-pinene (9.6-29.5%), (+)-phyllocladene (3.5-26.5%), ent-kaur-16-ene (0.2-20.6%), sabinene (0.5-19.9%) and limonene (1.4-11.5%), with a large variation in individual compounds from each population. Heartwood oils were characterized by a high content of cubebol (2.8-39.9%) and epi-cubebol (4.1-26.9%) isomers, which were absent in the foliage. Elemol and eudesmol isomers were found in the foliage and heartwood oils, while (+)-phyllocladene was absent in heartwood. Black and reddish bark oils were composed of the diterpenes dehydroferruginol (1.9-5.1%) and ferruginol (2.6-11.5%), along with the sesquiterpenes delta-cadinene (10.4-15.9%), alpha-muurolene (3.3-5.4%), epi-zonarene (4.0-5.0%), cubenol (9.3-14.0%), tau-muurolol (4.8-10.7%), beta-eudesmol (3.0-9.9%), gamma-eudesmol (1.9-7.0%) and hedycariol (1.4-6.2%). Azorean C. japonica oils exhibited significant chemical differences compared with native plants from Asia. The essential oils showed moderate antimicrobial activity against the pathogenic fungus Cryptococcus neoformans and human pathogenic bacteria (especially against multidrug-resistant Mycobacterium tuberculosis). The antimicrobial activity of the essential oils may be attributed to compounds such as ent-kaur-16-ene, (+)-phyllocladene, ferruginol and elemol, which are present in different proportions within the complex oil mixture. These results suggest a potential use for C. japonica oils obtained from wood industry leftovers. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/24555299/Essential_oil_characterization_of_two_Azorean_Cryptomeria_japonica_populations_and_their_biological_evaluations_ DB - PRIME DP - Unbound Medicine ER -