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A new bisanthraquinone and cytotoxic xanthones from Cratoxylum cochinchinense.
Nat Prod Res. 2014; 28(9):606-10.NP

Abstract

A new bisanthraquinone has been isolated from the stems of Cratoxylum cochinchinense together with vismiaquinone C and 16 known xanthones. Their structures were characterised by using spectroscopic methods. Two of the isolated compounds are modified xanthones (6 and 15) and exhibited strong cytotoxicity against human epidermoid carcinoma (A341: IC50 2.01, 1.78 μg/mL) and human breast cancer cell lines (SKBR3: IC50 1.54, 0.69 μg/mL).

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Publisher Full Text (DOI)

Authors+Show Affiliations

Rattanaburi S
a Department of Chemistry , Faculty of Science, Prince of Songkla University , Hat Yai, Songkhla 90112 , Thailand.
Daus M
No affiliation info available
Watanapokasin R
No affiliation info available
Mahabusarakam W
No affiliation info available

MeSH

AnthraquinonesAntineoplastic Agents, PhytogenicClusiaceaeDrug Screening Assays, AntitumorFemaleHumansMolecular StructurePlant StemsXanthones

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24571674

Citation

Rattanaburi, Suthida, et al. "A New Bisanthraquinone and Cytotoxic Xanthones From Cratoxylum Cochinchinense." Natural Product Research, vol. 28, no. 9, 2014, pp. 606-10.
Rattanaburi S, Daus M, Watanapokasin R, et al. A new bisanthraquinone and cytotoxic xanthones from Cratoxylum cochinchinense. Nat Prod Res. 2014;28(9):606-10.
Rattanaburi, S., Daus, M., Watanapokasin, R., & Mahabusarakam, W. (2014). A new bisanthraquinone and cytotoxic xanthones from Cratoxylum cochinchinense. Natural Product Research, 28(9), 606-10. https://doi.org/10.1080/14786419.2014.886212
Rattanaburi S, et al. A New Bisanthraquinone and Cytotoxic Xanthones From Cratoxylum Cochinchinense. Nat Prod Res. 2014;28(9):606-10. PubMed PMID: 24571674.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new bisanthraquinone and cytotoxic xanthones from Cratoxylum cochinchinense. AU - Rattanaburi,Suthida, AU - Daus,Mareena, AU - Watanapokasin,Ramida, AU - Mahabusarakam,Wilawan, Y1 - 2014/02/26/ PY - 2014/2/28/entrez PY - 2014/2/28/pubmed PY - 2014/9/25/medline KW - Cratoxylum cochinchinense KW - bisanthraquinone KW - cytotoxicity KW - xanthones SP - 606 EP - 10 JF - Natural product research JO - Nat Prod Res VL - 28 IS - 9 N2 - A new bisanthraquinone has been isolated from the stems of Cratoxylum cochinchinense together with vismiaquinone C and 16 known xanthones. Their structures were characterised by using spectroscopic methods. Two of the isolated compounds are modified xanthones (6 and 15) and exhibited strong cytotoxicity against human epidermoid carcinoma (A341: IC50 2.01, 1.78 μg/mL) and human breast cancer cell lines (SKBR3: IC50 1.54, 0.69 μg/mL). SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/24571674/A_new_bisanthraquinone_and_cytotoxic_xanthones_from_Cratoxylum_cochinchinense_ DB - PRIME DP - Unbound Medicine ER -