Tags

Type your tag names separated by a space and hit enter

Long-term biocompatibility and visual outcomes of a hydrophilic acrylic intraocular lens in patients with uveitis.
J Cataract Refract Surg. 2014 Apr; 40(4):618-25.JC

Abstract

PURPOSE

To report the long-term visual outcomes and biocompatibility of a single-piece hydrophilic acrylic intraocular lens (IOL) in patients with uveitis having cataract surgery.

SETTING

Tertiary referral center, Birmingham, United Kingdom.

DESIGN

Retrospective case review.

METHODS

The review included consecutive uveitis patients in whom phacoemulsification and acrylic IOL implantation was performed by the same surgeon. Outcomes measures are reported as rate/eye-year and included visual acuity and signs of bioincompatibility.

RESULTS

The review identified 171 eyes (140 patients; mean age 51 years [range 16 to 85 years]) with uveitis. The mean follow-up was 3.8 years (range 0.9 to 10.3 years). Signs of uveal bioincompatibility were found in 31 eyes, with visually insignificant deposits on the IOL in 17 eyes. The rate of uveal bioincompatibility was 0.06/eye-year. Signs of capsule bioincompatibility were found in 107 (63%) of 171 eyes (0.31/eye-year). Posterior capsule opacification was documented in 102 eyes (0.29/eye-year); neodymium:YAG laser capsulotomy was required in 31 eyes (0.05/eye-year). The rate of failure to maintain a 3 logMAR line improvement in corrected distance visual acuity (CDVA) was 0.08/eye-year; to maintain better than 0.3 logMAR, 0.15/eye-year; and to maintain either, 0.04/eye-year. At 1 year, 85% of eyes had a CDVA of better than 0.3 logMAR or maintained a 3 logMAR-line improvement. Eyes with preexisting macular or optic nerve disease had significantly worse visual outcomes.

CONCLUSIONS

The long-term safety profile of the hydrophilic acrylic IOL was good in uveitis cases, leading to good visual outcomes and a low rate of vision-impairing uveal and capsule complications.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

Authors+Show Affiliations

From the Academic Unit of Ophthalmology (Tomlins, Rauz) and School of Immunity and Infection (Murray), University of Birmingham, Good Hope Hospital (Sivaraj), and Queen Elizabeth Hospital Birmingham (Denniston), University Hospitals NHS Foundation Trust, Birmingham, United Kingdom.From the Academic Unit of Ophthalmology (Tomlins, Rauz) and School of Immunity and Infection (Murray), University of Birmingham, Good Hope Hospital (Sivaraj), and Queen Elizabeth Hospital Birmingham (Denniston), University Hospitals NHS Foundation Trust, Birmingham, United Kingdom.From the Academic Unit of Ophthalmology (Tomlins, Rauz) and School of Immunity and Infection (Murray), University of Birmingham, Good Hope Hospital (Sivaraj), and Queen Elizabeth Hospital Birmingham (Denniston), University Hospitals NHS Foundation Trust, Birmingham, United Kingdom.From the Academic Unit of Ophthalmology (Tomlins, Rauz) and School of Immunity and Infection (Murray), University of Birmingham, Good Hope Hospital (Sivaraj), and Queen Elizabeth Hospital Birmingham (Denniston), University Hospitals NHS Foundation Trust, Birmingham, United Kingdom.From the Academic Unit of Ophthalmology (Tomlins, Rauz) and School of Immunity and Infection (Murray), University of Birmingham, Good Hope Hospital (Sivaraj), and Queen Elizabeth Hospital Birmingham (Denniston), University Hospitals NHS Foundation Trust, Birmingham, United Kingdom. Electronic address: p.i.murray@bham.ac.uk.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

24581973

Citation

Tomlins, Paul J., et al. "Long-term Biocompatibility and Visual Outcomes of a Hydrophilic Acrylic Intraocular Lens in Patients With Uveitis." Journal of Cataract and Refractive Surgery, vol. 40, no. 4, 2014, pp. 618-25.
Tomlins PJ, Sivaraj RR, Rauz S, et al. Long-term biocompatibility and visual outcomes of a hydrophilic acrylic intraocular lens in patients with uveitis. J Cataract Refract Surg. 2014;40(4):618-25.
Tomlins, P. J., Sivaraj, R. R., Rauz, S., Denniston, A. K., & Murray, P. I. (2014). Long-term biocompatibility and visual outcomes of a hydrophilic acrylic intraocular lens in patients with uveitis. Journal of Cataract and Refractive Surgery, 40(4), 618-25. https://doi.org/10.1016/j.jcrs.2013.09.013
Tomlins PJ, et al. Long-term Biocompatibility and Visual Outcomes of a Hydrophilic Acrylic Intraocular Lens in Patients With Uveitis. J Cataract Refract Surg. 2014;40(4):618-25. PubMed PMID: 24581973.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term biocompatibility and visual outcomes of a hydrophilic acrylic intraocular lens in patients with uveitis. AU - Tomlins,Paul J, AU - Sivaraj,Ramesh R, AU - Rauz,Saaeha, AU - Denniston,Alastair K, AU - Murray,Philip I, Y1 - 2014/02/26/ PY - 2013/06/10/received PY - 2013/09/05/revised PY - 2013/09/08/accepted PY - 2014/3/4/entrez PY - 2014/3/4/pubmed PY - 2014/9/6/medline SP - 618 EP - 25 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 40 IS - 4 N2 - PURPOSE: To report the long-term visual outcomes and biocompatibility of a single-piece hydrophilic acrylic intraocular lens (IOL) in patients with uveitis having cataract surgery. SETTING: Tertiary referral center, Birmingham, United Kingdom. DESIGN: Retrospective case review. METHODS: The review included consecutive uveitis patients in whom phacoemulsification and acrylic IOL implantation was performed by the same surgeon. Outcomes measures are reported as rate/eye-year and included visual acuity and signs of bioincompatibility. RESULTS: The review identified 171 eyes (140 patients; mean age 51 years [range 16 to 85 years]) with uveitis. The mean follow-up was 3.8 years (range 0.9 to 10.3 years). Signs of uveal bioincompatibility were found in 31 eyes, with visually insignificant deposits on the IOL in 17 eyes. The rate of uveal bioincompatibility was 0.06/eye-year. Signs of capsule bioincompatibility were found in 107 (63%) of 171 eyes (0.31/eye-year). Posterior capsule opacification was documented in 102 eyes (0.29/eye-year); neodymium:YAG laser capsulotomy was required in 31 eyes (0.05/eye-year). The rate of failure to maintain a 3 logMAR line improvement in corrected distance visual acuity (CDVA) was 0.08/eye-year; to maintain better than 0.3 logMAR, 0.15/eye-year; and to maintain either, 0.04/eye-year. At 1 year, 85% of eyes had a CDVA of better than 0.3 logMAR or maintained a 3 logMAR-line improvement. Eyes with preexisting macular or optic nerve disease had significantly worse visual outcomes. CONCLUSIONS: The long-term safety profile of the hydrophilic acrylic IOL was good in uveitis cases, leading to good visual outcomes and a low rate of vision-impairing uveal and capsule complications. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned. SN - 1873-4502 UR - https://www.unboundmedicine.com/medline/citation/24581973/Long_term_biocompatibility_and_visual_outcomes_of_a_hydrophilic_acrylic_intraocular_lens_in_patients_with_uveitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0886-3350(14)00012-1 DB - PRIME DP - Unbound Medicine ER -