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Prescription drug monitoring and dispensing of prescription opioids.
Public Health Rep. 2014 Mar-Apr; 129(2):139-47.PH

Abstract

OBJECTIVE

In the United States, per-capita opioid dispensing has increased concurrently with analgesic-related mortality and morbidity since the 1990s. To deter diversion and abuse of controlled substances, most states have implemented electronic prescription drug monitoring programs (PDMPs). We evaluated the impact of state PDMPs on opioid dispensing.

METHODS

We acquired data on opioids dispensed in a given quarter of the year for each state and the District of Columbia from 1999 to 2008 from the Automation of Reports and Consolidated Orders System and converted them to morphine milligram equivalents (MMEs). We used multivariable linear regression modeling with generalized estimating equations to assess the effect of state PDMPs on per-capita dispensing of MMEs.

RESULTS

The annual MMEs dispensed per capita increased progressively until 2007 before stabilizing. Adjusting for temporal trends and demographic characteristics, implementation of state PDMPs was associated with a 3% decrease in MMEs dispensed per capita (p=0.68). The impact of PDMPs on MMEs dispensed per capita varied markedly by state, from a 66% decrease in Colorado to a 61% increase in Connecticut.

CONCLUSIONS

Implementation of state PDMPs up to 2008 did not show a significant impact on per-capita opioids dispensed. To control the diversion and abuse of prescription drugs, state PDMPs may need to improve their usability, implement requirements for committee oversight of the PDMP, and increase data sharing with neighboring states.

Authors+Show Affiliations

Columbia University, Departments of Anesthesiology and Epidemiology, Center for Injury Epidemiology and Prevention, New York, NY.Columbia University, Departments of Anesthesiology and Epidemiology, New York, NY.Columbia University, Departments of Anesthesiology and Epidemiology, Center for Injury Epidemiology and Prevention, New York, NY.Columbia University, Department of Anesthesiology, New York, NY.Columbia University, Department of Emergency Medicine, New York, NY.Columbia University, Departments of Anesthesiology and Epidemiology, Center for Injury Epidemiology and Prevention, New York, NY.

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

24587548

Citation

Brady, Joanne E., et al. "Prescription Drug Monitoring and Dispensing of Prescription Opioids." Public Health Reports (Washington, D.C. : 1974), vol. 129, no. 2, 2014, pp. 139-47.
Brady JE, Wunsch H, DiMaggio C, et al. Prescription drug monitoring and dispensing of prescription opioids. Public Health Rep. 2014;129(2):139-47.
Brady, J. E., Wunsch, H., DiMaggio, C., Lang, B. H., Giglio, J., & Li, G. (2014). Prescription drug monitoring and dispensing of prescription opioids. Public Health Reports (Washington, D.C. : 1974), 129(2), 139-47.
Brady JE, et al. Prescription Drug Monitoring and Dispensing of Prescription Opioids. Public Health Rep. 2014 Mar-Apr;129(2):139-47. PubMed PMID: 24587548.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prescription drug monitoring and dispensing of prescription opioids. AU - Brady,Joanne E, AU - Wunsch,Hannah, AU - DiMaggio,Charles, AU - Lang,Barbara H, AU - Giglio,James, AU - Li,Guohua, PY - 2014/3/4/entrez PY - 2014/3/4/pubmed PY - 2014/4/29/medline SP - 139 EP - 47 JF - Public health reports (Washington, D.C. : 1974) JO - Public Health Rep VL - 129 IS - 2 N2 - OBJECTIVE: In the United States, per-capita opioid dispensing has increased concurrently with analgesic-related mortality and morbidity since the 1990s. To deter diversion and abuse of controlled substances, most states have implemented electronic prescription drug monitoring programs (PDMPs). We evaluated the impact of state PDMPs on opioid dispensing. METHODS: We acquired data on opioids dispensed in a given quarter of the year for each state and the District of Columbia from 1999 to 2008 from the Automation of Reports and Consolidated Orders System and converted them to morphine milligram equivalents (MMEs). We used multivariable linear regression modeling with generalized estimating equations to assess the effect of state PDMPs on per-capita dispensing of MMEs. RESULTS: The annual MMEs dispensed per capita increased progressively until 2007 before stabilizing. Adjusting for temporal trends and demographic characteristics, implementation of state PDMPs was associated with a 3% decrease in MMEs dispensed per capita (p=0.68). The impact of PDMPs on MMEs dispensed per capita varied markedly by state, from a 66% decrease in Colorado to a 61% increase in Connecticut. CONCLUSIONS: Implementation of state PDMPs up to 2008 did not show a significant impact on per-capita opioids dispensed. To control the diversion and abuse of prescription drugs, state PDMPs may need to improve their usability, implement requirements for committee oversight of the PDMP, and increase data sharing with neighboring states. SN - 1468-2877 UR - https://www.unboundmedicine.com/medline/citation/24587548/Prescription_drug_monitoring_and_dispensing_of_prescription_opioids_ L2 - https://journals.sagepub.com/doi/10.1177/003335491412900207?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -