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ECMO for adult respiratory failure: current use and evolving applications.
ASAIO J. 2014 May-Jun; 60(3):255-62.AJ

Abstract

Extracorporeal membrane oxygenation (ECMO) is increasingly being used to support adults with severe forms of respiratory failure. Fueling the explosive growth is a combination of technological improvements and accumulating, although controversial, evidence. Current use of ECMO extends beyond its most familiar role in the support of patients with severe acute respiratory distress syndrome (ARDS) to treat patients with various forms of severe hypoxemic or hypercapnic respiratory failure, ranging from bridging patients to lung transplantation to managing pulmonary hypertensive crises. The role of ECMO used primarily for extracorporeal carbon dioxide removal (ECCO2R) in the support of patients with hypercapnic respiratory failure and less severe forms of ARDS is also evolving. Select patients with respiratory failure may be liberated from invasive mechanical ventilation altogether and some may undergo extensive physical therapy while receiving extracorporeal support. Current research may yield a true artificial lung with the potential to change the paradigm of treatment for adults with chronic respiratory failure.

Authors+Show Affiliations

From the *Department of Medicine, Columbia University College of Physicians and Surgeons, New York-Presbyterian Hospital, New York, New York; and †Department of Surgery, Columbia University College of Physicians and Surgeons, New York-Presbyterian Hospital, New York, New York.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24625534

Citation

Agerstrand, Cara L., et al. "ECMO for Adult Respiratory Failure: Current Use and Evolving Applications." ASAIO Journal (American Society for Artificial Internal Organs : 1992), vol. 60, no. 3, 2014, pp. 255-62.
Agerstrand CL, Bacchetta MD, Brodie D. ECMO for adult respiratory failure: current use and evolving applications. ASAIO J. 2014;60(3):255-62.
Agerstrand, C. L., Bacchetta, M. D., & Brodie, D. (2014). ECMO for adult respiratory failure: current use and evolving applications. ASAIO Journal (American Society for Artificial Internal Organs : 1992), 60(3), 255-62. https://doi.org/10.1097/MAT.0000000000000062
Agerstrand CL, Bacchetta MD, Brodie D. ECMO for Adult Respiratory Failure: Current Use and Evolving Applications. ASAIO J. 2014 May-Jun;60(3):255-62. PubMed PMID: 24625534.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - ECMO for adult respiratory failure: current use and evolving applications. AU - Agerstrand,Cara L, AU - Bacchetta,Matthew D, AU - Brodie,Daniel, PY - 2014/3/15/entrez PY - 2014/3/15/pubmed PY - 2014/12/18/medline SP - 255 EP - 62 JF - ASAIO journal (American Society for Artificial Internal Organs : 1992) JO - ASAIO J VL - 60 IS - 3 N2 - Extracorporeal membrane oxygenation (ECMO) is increasingly being used to support adults with severe forms of respiratory failure. Fueling the explosive growth is a combination of technological improvements and accumulating, although controversial, evidence. Current use of ECMO extends beyond its most familiar role in the support of patients with severe acute respiratory distress syndrome (ARDS) to treat patients with various forms of severe hypoxemic or hypercapnic respiratory failure, ranging from bridging patients to lung transplantation to managing pulmonary hypertensive crises. The role of ECMO used primarily for extracorporeal carbon dioxide removal (ECCO2R) in the support of patients with hypercapnic respiratory failure and less severe forms of ARDS is also evolving. Select patients with respiratory failure may be liberated from invasive mechanical ventilation altogether and some may undergo extensive physical therapy while receiving extracorporeal support. Current research may yield a true artificial lung with the potential to change the paradigm of treatment for adults with chronic respiratory failure. SN - 1538-943X UR - https://www.unboundmedicine.com/medline/citation/24625534/ECMO_for_adult_respiratory_failure:_current_use_and_evolving_applications_ L2 - https://doi.org/10.1097/MAT.0000000000000062 DB - PRIME DP - Unbound Medicine ER -