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The safety and efficacy of chloral hydrate sedation for pediatric ophthalmic procedures: a retrospective review.
J Pediatr Ophthalmol Strabismus 2014 May-Jun; 51(3):154-9JP

Abstract

PURPOSE

To determine the safety and efficacy of high-dose oral chloral hydrate for pediatric ophthalmic procedures.

METHODS

This study is a retrospective review of a quality audit of pediatric sedation for ophthalmic evaluation and imaging performed at King Khaled Eye Specialist Hospital between January 1 and December 31, 2011, in children aged 1 month to 6 years.

RESULTS

Three hundred fifty-eight of 380 (94.2%) sedation procedures were successful after a single dose of chloral hydrate, with 356 of 380 (93.7%) children sedated within 45 minutes of the first dose. The total success rate of the sedation procedure increased to 97.9% (372 of 380) when a second dose was administered. Children adequately sedated after a single dose of chloral hydrate were on average younger and weighed less than children who required additional doses. No major adverse events were documented.

CONCLUSIONS

The use of chloral hydrate sedation for ophthalmic evaluation and imaging was safe and effective in this patient population with a high rate of procedure completion.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24627951

Citation

Wilson, Michelle E., et al. "The Safety and Efficacy of Chloral Hydrate Sedation for Pediatric Ophthalmic Procedures: a Retrospective Review." Journal of Pediatric Ophthalmology and Strabismus, vol. 51, no. 3, 2014, pp. 154-9.
Wilson ME, Karaoui M, Al Djasim L, et al. The safety and efficacy of chloral hydrate sedation for pediatric ophthalmic procedures: a retrospective review. J Pediatr Ophthalmol Strabismus. 2014;51(3):154-9.
Wilson, M. E., Karaoui, M., Al Djasim, L., Edward, D. P., Al Shamrani, M., & Friedman, D. S. (2014). The safety and efficacy of chloral hydrate sedation for pediatric ophthalmic procedures: a retrospective review. Journal of Pediatric Ophthalmology and Strabismus, 51(3), pp. 154-9. doi:10.3928/01913913-20140311-01.
Wilson ME, et al. The Safety and Efficacy of Chloral Hydrate Sedation for Pediatric Ophthalmic Procedures: a Retrospective Review. J Pediatr Ophthalmol Strabismus. 2014;51(3):154-9. PubMed PMID: 24627951.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The safety and efficacy of chloral hydrate sedation for pediatric ophthalmic procedures: a retrospective review. AU - Wilson,Michelle E, AU - Karaoui,Mohammed, AU - Al Djasim,Leyla, AU - Edward,Deepak P, AU - Al Shamrani,Mohammad, AU - Friedman,David S, Y1 - 2014/03/18/ PY - 2013/11/18/received PY - 2014/02/10/accepted PY - 2014/3/18/entrez PY - 2014/3/19/pubmed PY - 2014/12/17/medline SP - 154 EP - 9 JF - Journal of pediatric ophthalmology and strabismus JO - J Pediatr Ophthalmol Strabismus VL - 51 IS - 3 N2 - PURPOSE: To determine the safety and efficacy of high-dose oral chloral hydrate for pediatric ophthalmic procedures. METHODS: This study is a retrospective review of a quality audit of pediatric sedation for ophthalmic evaluation and imaging performed at King Khaled Eye Specialist Hospital between January 1 and December 31, 2011, in children aged 1 month to 6 years. RESULTS: Three hundred fifty-eight of 380 (94.2%) sedation procedures were successful after a single dose of chloral hydrate, with 356 of 380 (93.7%) children sedated within 45 minutes of the first dose. The total success rate of the sedation procedure increased to 97.9% (372 of 380) when a second dose was administered. Children adequately sedated after a single dose of chloral hydrate were on average younger and weighed less than children who required additional doses. No major adverse events were documented. CONCLUSIONS: The use of chloral hydrate sedation for ophthalmic evaluation and imaging was safe and effective in this patient population with a high rate of procedure completion. SN - 1938-2405 UR - https://www.unboundmedicine.com/medline/citation/24627951/The_safety_and_efficacy_of_chloral_hydrate_sedation_for_pediatric_ophthalmic_procedures:_a_retrospective_review_ L2 - https://www.healio.com/doiresolver?doi=10.3928/01913913-20140311-01 DB - PRIME DP - Unbound Medicine ER -