Tags

Type your tag names separated by a space and hit enter

Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients.
J Eur Acad Dermatol Venereol. 2015 Jan; 29(1):42-7.JE

Abstract

BACKGROUND

Polycystic ovary syndrome (PCOS) is a common endocrinological disorder in women of childbearing-age. Although PCOS has common dermatological manifestations, including hirsutism, acne and androgenetic alopecia, little is known about the dermatological characteristics of PCOS patients in Asia.

OBJECTIVE

The goal of this study is to elucidate the dermatological characteristics and metabolic and hormonal parameters of Korean PCOS patients classified by the three ASRM/ESHERE criteria.

METHODS

We investigated 40 untreated PCOS patients who were newly diagnosed in the Department of Obstetrics & Gynecology of Seoul National University Hospital. Patients were classified according to the presence of irregular menstruation (IM), polycystic ovary morphology (PCOM) and hyperandrogenism (HA). Acne specific questionnaire, physical examination, and blood sampling were thoroughly conducted.

RESULTS

Twenty four patients (60.0%) met the criteria for the IM/HA/PCOM group and sixteen (40.0%) belonged to the IM/PCOM group. Acne was the most commonly observed dermatological manifestation (95.0%) followed by hirsutism (60.0%), seoborrhea (47.5%), acanthosis nigricans (20.0%) and androgenetic alopecia (12.5%). Hirsutism was more frequently observed in the IM/HA/PCOM group; the prevalence of other cutaneous manifestations did not differ significantly. Acne was most often observed on the face and most acne lesions were distributed on the forehead and cheek. Serum dehydroepiandrosterone sulphate level was higher in IM/HA/PCOM group, while serum cholesterol and high density lipoprotein concentrations were higher in the IM/PCOM group.

CONCLUSION

We described several dermatological manifestations and serum hormonal and metabolic parameters in Korean PCOS patients. Cutaneous manifestations might be the first signs of PCOS; therefore, dermatologists should be more aware of cutaneous manifestations of various ethnicities.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Hong JS
Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea; Acne and Rosacea Research Laboratory, Seoul National University Hospital, Seoul, Korea.
Kwon HH
No affiliation info available
Park SY
No affiliation info available
Jung JY
No affiliation info available
Yoon JY
No affiliation info available
Min S
No affiliation info available
Choi YM
No affiliation info available
Suh DH
No affiliation info available

MeSH

Acanthosis NigricansAcne VulgarisAdultAlopeciaAsian PeopleCholesterolDehydroepiandrosterone SulfateDermatitis, SeborrheicFacial DermatosesFemaleHirsutismHumansHyperandrogenismLipoproteins, HDLMenstruation DisturbancesPolycystic Ovary SyndromeRepublic of KoreaSkin DiseasesYoung Adult

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24628922

Citation

Hong, J S., et al. "Cutaneous Manifestations of the Subtypes of Polycystic Ovary Syndrome in Korean Patients." Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 29, no. 1, 2015, pp. 42-7.
Hong JS, Kwon HH, Park SY, et al. Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients. J Eur Acad Dermatol Venereol. 2015;29(1):42-7.
Hong, J. S., Kwon, H. H., Park, S. Y., Jung, J. Y., Yoon, J. Y., Min, S., Choi, Y. M., & Suh, D. H. (2015). Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients. Journal of the European Academy of Dermatology and Venereology : JEADV, 29(1), 42-7. https://doi.org/10.1111/jdv.12432
Hong JS, et al. Cutaneous Manifestations of the Subtypes of Polycystic Ovary Syndrome in Korean Patients. J Eur Acad Dermatol Venereol. 2015;29(1):42-7. PubMed PMID: 24628922.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients. AU - Hong,J S, AU - Kwon,H H, AU - Park,S Y, AU - Jung,J Y, AU - Yoon,J Y, AU - Min,S, AU - Choi,Y M, AU - Suh,D H, Y1 - 2014/03/14/ PY - 2013/11/11/received PY - 2014/01/31/accepted PY - 2014/3/18/entrez PY - 2014/3/19/pubmed PY - 2015/10/27/medline SP - 42 EP - 7 JF - Journal of the European Academy of Dermatology and Venereology : JEADV JO - J Eur Acad Dermatol Venereol VL - 29 IS - 1 N2 - BACKGROUND: Polycystic ovary syndrome (PCOS) is a common endocrinological disorder in women of childbearing-age. Although PCOS has common dermatological manifestations, including hirsutism, acne and androgenetic alopecia, little is known about the dermatological characteristics of PCOS patients in Asia. OBJECTIVE: The goal of this study is to elucidate the dermatological characteristics and metabolic and hormonal parameters of Korean PCOS patients classified by the three ASRM/ESHERE criteria. METHODS: We investigated 40 untreated PCOS patients who were newly diagnosed in the Department of Obstetrics & Gynecology of Seoul National University Hospital. Patients were classified according to the presence of irregular menstruation (IM), polycystic ovary morphology (PCOM) and hyperandrogenism (HA). Acne specific questionnaire, physical examination, and blood sampling were thoroughly conducted. RESULTS: Twenty four patients (60.0%) met the criteria for the IM/HA/PCOM group and sixteen (40.0%) belonged to the IM/PCOM group. Acne was the most commonly observed dermatological manifestation (95.0%) followed by hirsutism (60.0%), seoborrhea (47.5%), acanthosis nigricans (20.0%) and androgenetic alopecia (12.5%). Hirsutism was more frequently observed in the IM/HA/PCOM group; the prevalence of other cutaneous manifestations did not differ significantly. Acne was most often observed on the face and most acne lesions were distributed on the forehead and cheek. Serum dehydroepiandrosterone sulphate level was higher in IM/HA/PCOM group, while serum cholesterol and high density lipoprotein concentrations were higher in the IM/PCOM group. CONCLUSION: We described several dermatological manifestations and serum hormonal and metabolic parameters in Korean PCOS patients. Cutaneous manifestations might be the first signs of PCOS; therefore, dermatologists should be more aware of cutaneous manifestations of various ethnicities. SN - 1468-3083 UR - https://www.unboundmedicine.com/medline/citation/24628922/Cutaneous_manifestations_of_the_subtypes_of_polycystic_ovary_syndrome_in_Korean_patients_ DB - PRIME DP - Unbound Medicine ER -