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Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis.
Chin J Nat Med. 2014 Feb; 12(2):142-7.CJ

Abstract

AIM

To investigate the chemical constituents of Dioscorea zingiberensis C. H. Wright.

METHODS

The compounds were isolated by various chromatographic techniques, and the structures of the new steroidal saponins were elucidated by extensive 1D- and 2D-NMR, MS, and IR spectral analysis.

RESULTS

The 70% EtOH extract of the rhizomes of Dioscorea zingiberensis afforded two new steroidal saponins, zingiberenosides A (1) and B (2), along with eight known analogues, 3β, 26-dihydroxy-25(R)-furosta-Δ(5, 20(22))-diene-3-O-α-L- rhamnopyranosyl-(1→2)-O-β-D-glucopyranoside (3), methyl parvifloside (4), deltoside (5), methyl deltoside (6), zingiberensis new saponin (7), deltonin (8), progenin III (9) and diosgenin-diglucoside (10).

CONCLUSION

Two new steroidal saponins were isolated from Dioscorea zingiberensis and their structures determined.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Zheng L
Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
Zhou Y
Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
Zhang JY
School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100029, China.
Song M
Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
Yuan Y
Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
Xiao YJ
Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China.
Xiang T
Research Institute of Traditional Chinese Medicine, Yangtze River Pharmaceutical Group Co., Ltd., Taizhou, 225321, China. Electronic address: tingxiang39@163.com.

MeSH

DioscoreaDiosgeninMolecular StructurePlant ExtractsRhizomeSaponinsSpirostansSteroids

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

24636066

Citation

Zheng, Lu, et al. "Two New Steroidal Saponins From the Rhizomes of Dioscorea Zingiberensis." Chinese Journal of Natural Medicines, vol. 12, no. 2, 2014, pp. 142-7.
Zheng L, Zhou Y, Zhang JY, et al. Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis. Chin J Nat Med. 2014;12(2):142-7.
Zheng, L., Zhou, Y., Zhang, J. Y., Song, M., Yuan, Y., Xiao, Y. J., & Xiang, T. (2014). Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis. Chinese Journal of Natural Medicines, 12(2), 142-7. https://doi.org/10.1016/S1875-5364(14)60023-6
Zheng L, et al. Two New Steroidal Saponins From the Rhizomes of Dioscorea Zingiberensis. Chin J Nat Med. 2014;12(2):142-7. PubMed PMID: 24636066.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Two new steroidal saponins from the rhizomes of Dioscorea zingiberensis. AU - Zheng,Lu, AU - Zhou,Yuan, AU - Zhang,Jia-Yu, AU - Song,Min, AU - Yuan,Ye, AU - Xiao,Yan-Jiao, AU - Xiang,Ting, PY - 2012/11/10/received PY - 2014/3/19/entrez PY - 2014/3/19/pubmed PY - 2014/12/15/medline KW - Dioscorea zingiberensis KW - Dioscoreaceae KW - Steroidal saponins KW - Zingiberenoside SP - 142 EP - 7 JF - Chinese journal of natural medicines JO - Chin J Nat Med VL - 12 IS - 2 N2 - AIM: To investigate the chemical constituents of Dioscorea zingiberensis C. H. Wright. METHODS: The compounds were isolated by various chromatographic techniques, and the structures of the new steroidal saponins were elucidated by extensive 1D- and 2D-NMR, MS, and IR spectral analysis. RESULTS: The 70% EtOH extract of the rhizomes of Dioscorea zingiberensis afforded two new steroidal saponins, zingiberenosides A (1) and B (2), along with eight known analogues, 3β, 26-dihydroxy-25(R)-furosta-Δ(5, 20(22))-diene-3-O-α-L- rhamnopyranosyl-(1→2)-O-β-D-glucopyranoside (3), methyl parvifloside (4), deltoside (5), methyl deltoside (6), zingiberensis new saponin (7), deltonin (8), progenin III (9) and diosgenin-diglucoside (10). CONCLUSION: Two new steroidal saponins were isolated from Dioscorea zingiberensis and their structures determined. SN - 1875-5364 UR - https://www.unboundmedicine.com/medline/citation/24636066/Two_new_steroidal_saponins_from_the_rhizomes_of_Dioscorea_zingiberensis_ DB - PRIME DP - Unbound Medicine ER -